The Vision CBA System combines the simplicity of image cytometry with the power of flow analysis software to offer user-friendly cell-based assays, featuring:

  • Validated assay kits and reagents

  • Simple staining and analysis procedures

  • Default settings for automated data generation

  • No washing. No clogging. No daily calibration.

Apoptosis Assays

Detect programmed cell death based on Annexin-V binding, Caspase activation, Chromatin condensation, or changes in mitochondrial membrane potential

Aggresome Detection Assay

Detect inclusion body formation in response to the accumulation of aggregating proteins

Autophagy Assay

Detect the breakdown of intra-cellular components by formation of autophagosomes and autolysosomes (special transport vesicles)

Cell Cycle Assays

Determine population distribution by cell cycle phase based on DNA content: resting/growth phase (G0/G1), DNA replication phase (S), cell division phase (G2M)

Multidrug Resistance (MDR) Assay

Detect multidrug resistance based on activity of ABC transporter proteins and the removal of compounds from the cell

Proliferation Assays

Measure cell division based on reduction of original cytoplasmic protein content (and fluorescence intensity) in each generation

Surface Marker Assays

Quantify specific cell populations based on surface marker expression (CD56+ NK cells, CD34+ stem cells, etc.)

Transfection Assays

Determine the efficiency of transfection based on CFP, GFP, mCherry, RFP, TdTomato, or YFP expression

Viability Assays

Measure the number, concentration, and percentage of live and dead cells based on membrane integrity and/or metabolic activity