Hull designs, manufactures, installs, and services cGMP vacuum freeze drying equipment for the reliable lyophilization of a wide range of pharmaceutical and biotech products. We have a broad line of standard freeze dryer models and ancilliary equipment such as Clean-In-Place skids and autoloading and unloading systems. We also provide highly customized equipment upon request, utilizing fifty-plus years of industry experience and our in-house engineering and fabrication resources.

Hull offers full System Integration and Factory Acceptance testing, and IQ, OQ, and SIT documentation packages using the GAMP 5 model. Installation services and after-sale technical service and replacement parts are also available.

Key Features & Benefits

Standard Features

  • 25 PSIG ASME Code Pressure Vessel Rating
  • Automatic Perimeter Locking Door
  • Heavy-Duty Shelf Construction (Maintains flatness for the life of the system)
  • Double Latching
  • Stainless Steel Stoppering Ram Bellows
  • Smart Cool 4.0 Electronic Refrigeration Control
  • Lyo-Link is 21 CFR 11 Configurable PC/PLC based Control System

Standard Freeze Dryer Options

Refrigeration with Smart Cool®
• Reciprocating Compressors
• Screw Compressors
• LN2 Refrigeration
• Cascade Refrigeration

Heat Transfer
• Direct Expansion Condensing
• Flooded Loop Condensing
• Internal Condensing
• External and Hypro® Condensing

Vacuum
• Rotary Vane Vacuum Pumps
• Rotary Piston Vacuum Pumps
• Mechanical Booster Vacuum Pumps
• Liquid Ring Vacuum Pumps
• Dry Screw Pumps


Sterilization
• Clean-in-Place
• Steam-in-Place
• Vaporous Hydrogen Peroxide

Loading
• Auto-locking doors
• Sub-doors
• Pass-through
• Semi-Manual Loaders & Unloaders
• Automatic Loading & Unloading
Compliance
• GAMP 4
• 21 CFR 210
• 21 CFR 211
• ASME Sect. VIII Div. 1 Pressure Vessels
• Seismic Certification

Documentation
• Borescope Maps
• Materials Certifications
• System Integration Testing
• Factory Acceptance Testing
• Installation Qualification
• Operational Qualification

Retrofit Options
• Controls Upgrades
• Refrigeration Upgrades
• Product Shelves
• Process Vessels
• Vacuum Upgrades
• Clean-In-Place Retrofits
• ControLyo™ Nucleation On Demand Technology


Service Options
• Installation
• Startup
• Training
• Validation Assistance
• Preventative Maintenance

 

Hull excels at custom lyophilization systems:Request Your Custom Freeze Dryer Quote

Complete installation, startup, and training services are available to help you bring your lyophilization suite online quickly. We also provide preventative maintenance contracts and service and parts support to help you maintain your lyophilizer at optimum efficiency.