Primary Human Mesenchymal Stem Cells (hMSC)

PromoCell Primary Human Mesenchymal Stem Cells (hMSC) are harvested from bone marrow, adipose tissue, or the umbilical cord matrix.

Description

Mesenchymal Stem Cells (MSC), also known as Mesenchymal Stromal Cells, are multipotent cells that can be separated into a range of cell types and possess the capacity for self-renewal. MSCs have been proven to differentiate in vitro or in vivo into adipocytes, osteoblasts, chondrocytes, myocytes, hepatocytes, neurons, and pancreatic islet cells.

PromoCell media are available to allow the growth of MSC and support their differentiation into numerous different lineages. Latest experiments indicate that differentiation capabilities into diverse cell types differ between MSC of varying origins.

PromoCell hMSCs are harvested from regular human bone marrow, adipose tissue, and the umbilical cord matrix (Wharton’s jelly).

The cells are tested for their ability to differentiate in vitro into chondrocytes, adipocytes, and osteoblasts. PromoCell hMSC exhibit a verified marker expression profile that adheres with the International Society for Cellular Therapy (ISCT) guidelines, providing appropriately characterized cells.

PromoCell’s hMSC are currently also available from HLA-typed donors.

Available Formats

  • Cell pellet: 1 million cells dissolved in 200 µl RNAlater© for ensuing DNA, RNA, or protein analysis. It is not possible to revive cell pellets.
  • Cryopreserved: Cryogenic vial comprising of 500.000 viable cells
  • Proliferating: >500.000 viable cells shipped in growth medium (T75 flask)

Additional Information

  • Recommended plating density: 4,000 cells per cm2
  • Tested markers: Differentiation capacity to adipogenic, osteogenic and chondrogenic cells tested, CD105 positive, CD73 positive, CD90 positive, CD45 negative, CD34 negative, CD14 negative, CD19 negative, HLA-DR negative