Consumer Medicine Information
What is in this leaflet
This leaflet answers some common questions about Akineton.
It does not contain all the available information.
It does not take the place of talking to your doctor or pharmacist.
All medicines have risks and benefits. Your doctor has weighed the risks of you taking
Akineton against the benefits they expect it will have for you.
If you have any concerns about taking this medicine, ask your doctor or pharmacist.
Keep this leaflet with the medicine.
You may need to read it again.
What Akineton is used for
Akineton is used to treat symptoms of parkinsonism.
The symptoms of parkinsonism include slow and unsteady movement, muscle stiffness
and shaking (tremors). If untreated parkinsonism can cause difficulty in performing
normal daily activities.
Symptoms of parkinsonism can be caused by certain diseases of the brain affecting
movement, such as Parkinson's disease. They can also be caused by some medicines that
are used to treat certain mental conditions.
It is believed the symptoms of parkinsonism are caused by a lack of dopamine, a naturally
occurring chemical produced by certain brain cells. When not enough dopamine is present,
acetylcholine which is another naturally occurring chemical produced by brain cells,
can interfere with the regions of the brain that control muscle movement.
Akineton blocks the effects of acetylcholine. In many patients, this reduces the symptoms
of shaking and muscle stiffness.
Akineton is also used to treat cramps that occur during the night.
Akineton belongs to a group of medicines called anticholinergics. It is available
Ask your doctor if you have any questions about why AKINETON has been prescribed for
Your doctor may have prescribed Akineton for another reason.
This medicine is available only with a doctor’s prescription.
Before you take Akineton
When you must not take it
Do not take Akineton if you have an allergy to:
any medicine containing biperiden
any of the ingredients listed at the end of this leaflet.
Some of the symptoms of an allergic reaction may include:
shortness of breath
wheezing or difficulty breathing
swelling of the face, lips, tongue or other parts of the body
rash, itching or hives on the skin.
Do not take Akineton if you have narrow angle glaucoma.
Glaucoma is a condition in which the pressure of fluid in the eye may be high.
Do not take Akineton if you have a narrowing of the stomach, large bowel or small
Do not take this medicine after the expiry date (EXP) printed on the pack or if the
packaging is torn or shows signs of tampering.
If you are not sure whether you should start taking Akineton, talk to your doctor.
Before you start to take it
Tell your doctor if you have allergies to any other medicines, foods, preservatives
Tell your doctor if you are pregnant or plan to become pregnant or are breastfeeding.
Like most medicines, Akineton is not recommended for use during pregnancy or while
you are breastfeeding, unless you and your doctor have discussed the risks and benefits
Tell your doctor if you have or have had any medical conditions, especially the following:
heart problems, such as fast heart beat
difficulty passing urine
enlarged prostate or any other prostate problems
convulsions, fits or seizures
uncontrolled movements of hands, mouth or tongue
if you consume large quantities of alcohol
neuromuscular disorder which causes abnormal weakness of muscles
If you have not told your doctor about any of the above, tell them before you start
Taking other medicines
Tell your doctor if you are taking any other medicines, including any that you get
without a prescription from your pharmacy, supermarket or health food shop.
Some medicines and Akineton may interfere with each other.
Some medicines used to treat mental illness or psychotic disorders.
A group of medicines called tricyclic antidepressants used to treat depression.
Other anticholinergic medicines, such as benzhexol, benztropine, procyclidine, orphenadrine.
Other medicines such as levodopa/carbidopa monohydrate, for the treatment of the symptoms
Pethidine, a medicine used to relieve pain and produce sleepiness.
Antihistamines, medicines used to prevent or relieve the symptoms of allergy (such
as hay fever).
Medicines used to relieve muscle spasms.
Metoclopramide, a medicine used to treat nausea and vomiting.
Quinidine, a medicine used to treat heart conditions.
These medicines may be affected by Akineton, or may affect how well it works. You
may need different amounts of your medicine, or you may need to take different medicines.
Your doctor will advise you.
Your doctor and pharmacist may have more information on medicines to be careful with
or avoid while taking this medicine.
How to take AKINETON
How much to take
Take Akineton only when prescribed by your doctor.
Your doctor will tell you how many tablets you will need to take each day. This depends
on your symptoms, age, weight and whether you are taking any other medicines. The
dose varies considerably from patient to patient.
To treat parkinsonism symptoms, the usual adult dose is 1/2 to 2 tablets taken 3-4
times a day.
For night cramps the usual dose is 2 tablets.
Follow all directions given to you by your doctor and pharmacist carefully.
These directions may differ from the information contained in this leaflet.
If you do not understand the instructions on the pack, ask your doctor or pharmacist
How to take it
Swallow Akineton with a glass of water.
When to take it
Take Akineton with food at about the same time each day unless your doctor tells you
Taking your tablets at the same time each day will have the best effect. It will
also help you remember when to take the tablets.
For night cramps take Akineton with the evening meal. Alternatively one tablet can
be taken with the evening meal and one tablet on going to bed.
How long to take it
Akineton helps control your symptoms of parkinsonism, and cramps that occur at night
but does not cure them. Continue taking the tablets for as long as your doctor tells
If you forget to take it
If it is almost time for your next dose, skip the dose you missed and take your next
dose when you are meant to.
Otherwise, take it as soon as you remember, and then go back to taking your medicine
as you would normally.
Do not take a double dose to make up for the dose that you missed.
This may increase the chance of you getting an unwanted side effect.
If you are not sure what to do, ask your doctor or pharmacist.
If you have trouble remembering to take your medicine, ask your pharmacist for some
If you take too much (overdose)
Immediately telephone your doctor or pharmacist or the Poisons Information Centre
(telephone 13 11 26) for advice, or go to Accident and Emergency at your nearest hospital,
if you think that you or anyone else may have taken too much Akineton. Do this even
if there are no signs of discomfort or poisoning.
You may need urgent medical attention.
Some of the symptoms of overdose are agitation, confusion, hallucination, slowing
of movements, reddening of face, fever. Your doctor or pharmacist has information
on how to recognise and treat an overdose. Ask your doctor or pharmacist if you have
While you are using Akineton
Things you must do
Try to avoid becoming overheated during exercise or hot weather while you are using
Akineton may make you sweat less, causing your body temperature to increase. If you
overheat during exercise or hot weather you may get heat stroke.
If you are about to be started on any new medicine, remind your doctor and pharmacist
that you are taking Akineton.
Tell any other doctors, dentists and pharmacists who are treating you that you are
taking this medicine.
If you become pregnant while taking Akineton, tell your doctor immediately.
Things you must not do
Do not drink any alcohol whilst you are taking Akineton.
Do not give your medicine to anyone else, even if they have the same condition as
Do not take Akineton to treat any other complaints unless your doctor tells you to.
Do not stop taking your medicine, or lower the dosage, without checking with your
Things to be careful of
Be careful driving or operating machinery until you know how Akineton affects you.
This medicine may cause some people to have blurred vision or to become less alert
Make sure you know how you react to Akineton before you drive a car, operate machinery,
or do anything else that could be dangerous if you have blurred vision or are less
alert then normal. If this occurs do not drive.
Tell your doctor as soon as possible if you do not feel well while you are taking
Akineton helps most people with symptoms of parkinsonism or night cramps but it may
have unwanted side effects in a few people. All medicines can have side effects. Sometimes
they are serious, most of the time they are not. You may need medical treatment if
you get some of the side effects.
Ask your doctor or pharmacist to answer any questions you may have.
Tell your doctor or pharmacist if you notice any of the following and they worry you:
dry mouth, or difficulty swallowing or speaking due to dry mouth
dilated pupils and uncomfortable sensitivity to light
less sweat or perspiration
dizziness or light headedness
drowsiness or tiredness
occasional loss of memory
feeling sick, also called nausea or vomiting
These side effects are usually mild.
Tell your doctor as soon as possible if you notice any of the following:
fast or slow heart beat
severe stomach pain, stomach upset or constipation
swelling of salivary glands
severe dizziness or a spinning sensation
uncontrollable twitching, jerking or writhing movements
clumsiness and lack of coordination, affecting balance and manner of walking, limb
or eye movements and/or speech
restlessness and confusion
seeing things that are not there, also called hallucinations
convulsions, fits or seizures
These may be serious side effects. You may need urgent medical attention. Serious
side effects are rare.
If any of the following happen, tell your doctor immediately or go to Accident and
Emergency at your nearest hospital:
heat stroke, raised body temperature
an allergic reaction such as a skin rash
it becomes impossible for you to empty your bladder
These are serious side effects. You may need urgent medical attention or hospitalisation.
These side effects are rare.
Tell your doctor or pharmacist if you notice anything that is making you feel unwell.
Other side effects not listed above may occur in some people.
Do not be alarmed by this list of possible side effects.
You may not experience any of them.
After using Akineton
Keep your tablets in the pack until it is time to take them.
If you take tablets out of the pack they will not keep well.
Keep your tablets in a cool dry place where the temperature stays below 25°C.
Do not store Akineton or any other medicine in the bathroom or near a sink. Do not
leave it in the car on hot days or on window sills.
Heat and dampness can destroy some medicines.
Keep it where children cannot reach it.
A locked cupboard at least 1 1/2 metres above the ground is a good place to store
If your doctor tells you to stop taking this medicine or the expiry date has passed,
ask your pharmacist what to do with any that are left over.
What it looks like
Akineton is a white round quarter scored tablet marked with the Knoll logo.
A pack contains 100 tablets.
Akineton contains 2 mg of biperiden hydrochloride as the active ingredient:
It also contains:
pregelatinised potato starch
calcium hydrogen phosphate dihydrate
Akineton does not contain gluten, sucrose, tartrazine or any other azo dyes
Amdipharm Mercury (Australia) Pty Ltd
Level 9, 76 Berry Street
North Sydney NSW 2060
Australian Registration Number:
AUST R 12792
Date of preparation
This leaflet was last updated on
9 June 2017
Amdipharm Mercury (Australia) Pty Ltd is licensed to use the trademark Akineton