Glucosamine sulfate (as glucosamine sulfate-sodium chloride complex)
CONSUMER MEDICINE INFORMATION
What is in this CMI
The information in this CMI answers some of the questions you may have about DONA
Glucosamine. It does not contain all the available information.
All medicines have risks and benefits. If you have other questions or any concerns
about using this medicine, ask your health care practitioner, doctor or pharmacist.
What DONA Glucosamine is used for
DONA Glucosamine contains glucosamine sulfate-sodium chloride complex – the stabilised
crystalline form of glucosamine sulfate which is clinically proven to assist in the
relief of the symptoms of osteoarthritis of the knee, hip, spine and hands. It acts
on both the signs and symptoms of osteoarthritis, helps in building and maintaining
healthy cartilage which is essential for healthy function of the joints, and may reduce
the breakdown of existing cartilage.
DONA Glucosamine may reduce inflammation, aid in the management of swelling and tenderness,
may assist with the symptomatic relief of pain associated with osteoarthritis, and
has demonstrated improvement in the mobility of joints. It has been shown to rebuild
damaged cartilage, thus restoring articular function.
Before you use DONA Glucosamine
When you must not use it
Since glucosamine is obtained from shellfish, people who are allergic to shellfish
should not take this medicine.
Do not take DONA Glucosamine tablets or powder for oral solution if you are hypersensitive
to glucosamine or to any of the excipient ingredients listed in the Product Description
DONA Glucosamine powder for oral solution in sachets contains aspartame, a source
of phenylalanine, therefore people with phenylketonuria should consider taking DONA
Glucosamine tablets instead.
DONA Glucosamine powder for oral solution in sachets also contains sorbitol, therefore
people who have an intolerance to some sugars should consult their health care practitioner,
doctor or pharmacist before taking the medicine.
Do not use this medicine after the expiry date printed on the pack or if the packaging
is torn or shows signs of tampering. In that case, return it to your pharmacist or
Before you start to use
Tell your health care practitioner, doctor or pharmacist if you have any of the following
medical problems or conditions:
you or your family have a history of hypersensitivity to seafood, glucosamine, sorbitol
or other ingredients of DONA Glucosamine.
phenylketonuria, where your ability to break down the amino acid phenylalanine is
diabetes. Closer monitoring of blood sugar levels may be necessary when glucosamine
is first taken.
severe liver or kidney problems, so that your hepatic (liver) or renal (kidney) function
can be checked regularly by your doctor while you are taking glucosamine.
asthma. Glucosamine should be used with caution by asthmatic patients since they may
be more susceptible to develop allergic reactions to glucosamine, with a possible
worsening of their symptoms.
you are pregnant or breast-feeding. There is inadequate data on glucosamine use during
pregnancy or lactation.
other joint diseases, which require other treatment.
you are on a controlled sodium diet. The recommended daily dose of DONA Glucosamine
contains 151 mg of sodium in a sachet of powder for oral solution, or 155 mg of sodium
from 2 tablets.
Taking other medicines
You should always tell your health care practitioner, doctor or pharmacist what medicines
you are taking, including medicines that you buy without a prescription from a pharmacy,
supermarket or health food store.
The absorption of tetracyclines and the effect of coumarinic anticoagulants (such
as warfarin) may increase when taken together with glucosamine sulfate, but it is
unlikely that DONA Glucosamine and other medicines will interact with each other.
How to take DONA Glucosamine
Powder for oral solution:
The recommended daily dose is one sachet per day. Dissolve the contents of one sachet
in a glass of water (approximately 250 mL) and drink it up, preferably during a meal.
Take two tablets per day unless directed otherwise by your health care practitioner,
doctor or pharmacist. Swallow the tablets whole with plenty of water or suitable
liquid, preferably during either morning or evening meals.
DONA Glucosamine is not recommended for children or adolescents under 18 years old
where efficacy and safety has not been established.
How long to take it
Improvement of symptoms may be expected after 4 weeks of treatment, with optimal effects
on joint mobility usually observed after 12 weeks. DONA Glucosamine can be continued
long term to maintain the physical benefits. If you stop taking DONA, your symptoms
If symptoms persist, or the condition recurs, consult your health care practitioner,
doctor or pharmacist.
If you forget to take it
If it is almost time for your next dose, skip the dose you missed and take your next
dose as planned. Otherwise, take it as soon as you remember then continue your normal
routine. Do not take a double dose to compensate for the forgotten one.
If you take too much (overdose)
If you think you or anyone else has taken too much, or are suffering signs of discomfort
or poisoning, immediately telephone your doctor or Poisons Information Centre on 13
11 26 (Australia) or the National Poisons Centre on 0800 764 766 (New Zealand) for
advice, or go to Accident and Emergency at your nearest hospital.
While you are taking DONA Glucosamine
Things you must do
You should remind all health care practitioners, doctors, and pharmacists who are
treating you for any condition that you are taking DONA Glucosamine, especially if
you are starting, stopping or changing the dose of any other medicine.
The effect of warfarin (a drug used to prevent blood clotting) may increase during
treatment with glucosamine. Your doctor may consider measuring your blood clotting
status more frequently.
If you become pregnant while you are using DONA Glucosamine, tell your health care
practitioner, doctor and pharmacist. They can discuss with you the risks of using
it while you are pregnant.
If the symptoms of your osteoarthritis persist, seems to be getting worse or reappear,
speak to your health care practitioner, doctor or pharmacist.
Things you must not do
Do not give this medicine to anyone else, even if their symptoms seem to be the same
as yours. Do not use it to treat any other complaints unless your health care practitioner,
doctor or pharmacist tells you to.
Effects on ability to drive and operate machinery
DONA Glucosamine has no known effects in these situations, but refrain from driving
or operating machinery if you experience side effects such as dizziness or drowsiness
that can interfere with these activities.
Possible side effects
Clinical trials with DONA Glucosamine have shown the medicine to be well tolerated.
Undesirable effects have been observed in a low proportion of patients and were usually
mild and transient. The most common side effects are nausea, abdominal pain, indigestion,
flatulence, constipation, diarrhoea, headache, tiredness and drowsiness.
Hypersensitivity reactions have been reported in some patients and included skin rashes
with itching and redness.
You should inform your health care practitioner, doctor or pharmacist if you notice
anything that is making you feel unwell while taking DONA Glucosamine, even if it
is not on the list of side effects or is not yet known.
After using DONA Glucosamine
DONA Glucosamine should be stored below 30°C.
Do not store this medicine or any other medicine in the bathroom or near a sink.
Do not leave it in the car or on window sills. Heat and dampness can destroy some
Keep the medicine where young children cannot reach it. A locked cupboard at least
one-and-a-half metres above the ground is a good place to store medicines.
If you no longer need the medicine or it has passed its expiry date, return any unused
medicine to your pharmacist.
DONA Glucosamine is available in tablet form or as powder for oral solution.
Each white, film-coated tablet contains 942 mg of glucosamine sulfate-sodium chloride
complex (equivalent to 750 mg glucosamine sulfate) and the excipient ingredients:
microcrystalline cellulose, povidone, croscarmellose sodium, macrogol 6000, magnesium
stearate, purified talc, methacrylic acid copolymer, ammonio methacrylate copolymer,
glycerol triacetate and titanium dioxide.
Powder for oral solution:
One box contains 30 sachets. Each sachet contains 1.88 g of glucosamine sulfate-sodium
chloride complex (equivalent to 1500 mg glucosamine sulfate). The white powder also
contains aspartame, sorbitol, anhydrous citric acid and macrogol 4000 as excipient
MEDA Pharmaceuticals Pty Ltd
Suite 1, Level 3, 110 Pacific Highway
St Leonards NSW 2065, AUSTRALIA
Telephone: 1800 048 987
This CMI was prepared in December 2016.
Australian Registration Numbers:
Powder for oral solution 1500 mg (sachets): AUST L 161135
Tablets 750 mg (bottle): AUST L 119580