Consumer Medicine Information
What is in this leaflet
Read this leaflet carefully before you are given Fluorescite Injection.
This leaflet answers some common questions about Fluorescite Injection. It does not
contain all the available information. It does not take the place of talking to your
doctor or pharmacist.
The information in this leaflet was last updated on the date listed on the final page.
More recent information on the medicine may be available.
You should ensure that you speak to your pharmacist or doctor to obtain the most up
to date information on the medicine.
You can also download the most up to date leaflet from www.novartis.com.au
The updates may contain important information about the medicine and its use of which
you should be aware.
All medicines have risks and benefits. Your doctor has weighed the risks of you using
Fluorescite against the benefits they expect it will have for you.
If you have any concerns about using this medicine, ask your doctor or pharmacist.
Keep this leaflet with your medicine.
You may need to read it again.
What Fluorescite is used for
Fluorescite Injection contains fluorescein sodium which possesses the property of
Fluorescite Injection is a "diagnostic agent".
Fluorescite allows your doctor to see the blood moving through the small blood vessels
at the back of your eye(s). It assists your doctor in determining if areas of your
eye(s) are damaged or unhealthy.
Use in children
The safety and effectiveness of Fluorescite Injection has not been established.
Before Fluorescite is used
When it must not be used
Fluorescite Injection should not be used if you have an allergy to:
any of the ingredients listed at the end of this leaflet under "Product Description"
any other similar medicines
Some of the symptoms of an allergic reaction may include:
shortness of breath, wheezing or difficulty breathing
swelling of the face, lips, tongue or other parts of the body
rash, itching or hives on the skin.
Fluorescite Injection should not be used if:
the vial/packaging shows signs of tampering
the expiry date on the injection vial/carton has passed.
If this medicine is used after the expiry date has passed, it may not work as well.
If you are not sure whether Fluorescite Injection should be used in your case, talk
to your doctor.
Before you are given it
Tell your doctor if you have had an allergy to any other medicines or any other substances,
such as foods, preservatives or dyes.
Tell your doctor if you have or have had any of the following medical conditions:
Are on a controlled low sodium diet.
Tell your doctor if you are pregnant or plan to become pregnant.
Your doctor can discuss with you the risks and benefits of using Fluorescite when
you are pregnant.
Tell your doctor if you are breastfeeding or intend to breastfeed.
Fluorescite comes through breast milk for up to 7 days after it is used.
Discontinue breastfeeding for at least 7 days after Fluorescite use.
If you have not told your doctor about any of the above, tell them before they administer
Taking or using other medicines
Tell your doctor or pharmacist if you are taking any other medicines, including any
medicines that you get without a prescription from a pharmacy, supermarket or health
Some medicines and Fluorescite may interfere with each other. These include:
Probenecid or other compounds that inhibit or compete with the active transport of
beta-adrenergic blocking agents that are used to treat heart conditions, lower blood
pressure and treat glaucoma.
Using Fluorescite when you are on a beta-adrenergic blocking medicine can cause a
severe allergic reaction and affect the body's ability to respond to this reaction.
Your doctor or pharmacist have more information on medicines to be careful with or
avoid when Fluorescite is to be used.
How Fluorescite is used
How much to use
The dose of Fluorescite Injection will be determined and administered by your doctor.
The usual adult dose of Fluorescite Injection is 10% or one 5 mL vial.
The usual dose for a child is based on the child’s weight.
How it is used
Before using Fluorescite Injection your doctor will put some eye drops in your eye(s)
that will open (dilate) your pupil(s). This allows your doctor to see the back of
your eye(s) clearly.
Your doctor will usually administer Fluorescite Injection into your arm. It normally
takes between 7 and 14 seconds for the fluorescein to reach the back of your eye(s).
Following the administration of Fluorescite Injection your doctor will turn the lights
off and take a series of photographs of the back of your eye(s). These photographs
will allow your doctor to study the movement of blood through the vessels at the back
of your eye(s).
If you use too much (overdose)
Your doctor will ensure that you are administered the correct dose of Fluorescite
After Fluorescite is used
Things to be aware of
It is likely that you will notice a yellow discolouration of your skin. Normally
this will not last longer than 6 to 12 hours.
You will also notice a bright yellow colouring of your urine. Normally this will
not last longer than 24 to 36 hours.
You may also notice a strong taste following the administration of Fluorescite Injection.
Fluorescite Injection can stain contain lenses.
Things to be careful of
You should not drive or operate any machinery after you have been given Fluorescite.
Temporary blurred vision or other visual disturbances may occur. Wait until your
vision is clear before driving or operating machinery.
Tell your doctor as soon as possible if you do not feel well following the use of
All medicines can have side effects. Sometimes they are serious, most of the time
they are not. You may need medical treatment if you get some of the side effects.
Do not be alarmed by the following list of possible side effects. You may not experience
any of them.
Ask your doctor to answer any questions you may have.
Side effects that may occur at or near the site of the injection include:
a dull ache in your arm
feeling of weakness.
If you feel any pain or discomfort during the administration of Fluorescite Injection
tell your doctor immediately.
Tell your doctor as soon as possible if you notice any of the following:
strong taste in the mouth, metallic taste
nausea and or headache
gastrointestinal discomfort or vomiting
dizziness, feeling light headed or fainting, which may be associated with low blood
pressure or reduction in the flow of blood to the brain.
low or high blood pressure
rash, itchy red skin
tingling in fingers or toes
cough, throat irritation
These are serious side effects that may require medical attention. Serious side effects
If any of the following happen, tell your doctor immediately or go to Accident and
Emergency at your nearest hospital:
severe shock and or convulsions
swelling in the vein used to administer the injection. This may be due to a clot in
hypersensitivity or allergic type reactions
Some of the symptoms of an allergic reaction include:
swelling in the throat
tightness in the chest.
These reactions may begin by an itching or tingling around the lips or tongue.
cardiac arrest (the heart stops beating)
damage to the brain due to poor blood supply
These are very serious side effects. These side effects are very rare.
Tell your doctor immediately if you notice any discomfort in or around your chest
or feel light headed shortly after the administration of Fluorescite Injection.
Tell your doctor or pharmacist if you notice anything that is making you feel unwell
after you are given Fluorescite Injection.
Other side effects not listed above may also occur in some people.
What it looks like
Fluorescite Injection 10% is a red-orange, sterile solution packed in a 5 mL glass
vial with a stopper and aluminium flip-off cap.
Fluorescite Injection 10% is for single dose use only. It contains no preservative
and must be discarded after use. It has a pH of 8.0 to 9.8.
The active ingredient in Fluorescite Injection is fluorescein 100 mg in 1 mL (equivalent
to 113.2 mg/mL of fluorescein sodium).
Fluorescite Injection also contains:
sodium hydroxide and/or hydrochloric acid (to adjust pH)
water for injections.
Store at or below 25°C. Do not freeze. Protect from light.
Fluorescite 10% Injection is supplied in Australia by:
Novartis Pharmaceuticals Australia Pty Limited
ABN 18 004 244 160
54 Waterloo Road
Macquarie Park NSW 2113
Web site: www.novartis.com.au
Australian registration number
AUST R No: 124267.
Date of preparation
This leaflet was revised in August 2017.
© Novartis Pharmaceuticals Australia Pty Limited 2017
™ trademark of Novartis
Internal document code:
(flo260717c) based on PI (flo260717i)