Amlodipine (am-load-i-peen) Besilate
Consumer Medicine Information
What is in this leaflet
This leaflet answers some common questions about Norvasc.
It does not contain all the available information. It does not take the place of talking
to your doctor or pharmacist.
All medicines have risks and benefits. Your doctor has weighed the risks of you taking
Norvasc against the benefits it is expected to have for you.
If you have any concerns about taking this medicine, ask your doctor or pharmacist.
Keep this leaflet with the medicine.
You may need to read it again.
What Norvasc is used for
What it does
Norvasc is used to:
lower high blood pressure (hypertension).
There are usually no symptoms of hypertension. The only way of knowing that you have
hypertension is to have your blood pressure checked on a regular basis. If high blood
pressure is not treated it can lead to serious health problems.
treat angina pectoris.
Angina is a pain or uncomfortable feeling in the chest, often spreading to the arms
or neck, and sometimes to the shoulders and back. The pain of angina is due to a shortage
of oxygen to the heart.
Norvasc is not for the relief of a sudden attack of angina. Your doctor will give
you other medication to treat this.
How it works
Norvasc belongs to a group of medicines called calcium channel blockers or calcium
ion antagonists. They work by widening your blood vessels, making it easier for your
heart to pump blood around the body and help increase the supply of blood and oxygen
to your heart. Calcium channel blockers do not change the amount of calcium in your
blood or bones.
Ask your doctor if you have any questions about why Norvasc has been prescribed for
Your doctor may have prescribed it for another reason.
This medicine is available only with a doctor's prescription.
Use in Children
There is not enough information to recommend the use of this medicine in children.
Before you take Norvasc
When you must not take it
Do not take Norvasc if you have an allergy to:
Norvasc, or any other medicine containing amlodipine
other calcium channel blockers such as medicines with the active ingredient felodipine,
nifedipine or lercanidipine.
Check with your doctor or pharmacist if you are unsure.
any of the ingredients listed at the end of this leaflet.
Some of the symptoms of an allergic reaction may include:
shortness of breath
wheezing or difficulty breathing
swelling of the face, lips, tongue or other parts of the body
rash, itching or hives on the skin.
Do not take this medicine after the expiry date printed on the pack or if the packaging
is torn or shows signs of tampering.
If it has expired or is damaged, return it to your pharmacist for disposal.
If you are not sure whether you should start taking this medicine, talk to your doctor.
Before you start to take it
Tell your doctor if you have allergies to any other medicines, foods, preservatives
Tell your doctor if you have or have had any of the following medical conditions:
heart problems, including heart failure
Tell your doctor if you are pregnant or plan to become pregnant.
This medicine may affect your developing baby if you take it during pregnancy. Your
doctor can discuss with you the risks and benefits involved.
Do not breast-feed if you are taking this medicine.
The active ingredient in Norvasc passes into breast milk. Your baby may be affected.
If you have not told your doctor about any of the above, tell him/her before you start
Taking other medicines
Tell your doctor or pharmacist if you are taking any other medicines, including:
all prescription medicines
all medicines, vitamins, herbal supplements or natural therapies you buy without a
prescription from a pharmacy, supermarket, naturopath or health food shop.
Some medicines may be affected by Norvasc or may affect how well it works. You may
need different amounts of your medicines, or you may need to take different medicines.
Your doctor will advise you.
Tell your doctor or pharmacist if you are taking any of the following:
other medicines used to treat angina, such as diltiazem
some antibiotics, such as erythromycin, clarithromycin or rifampicin
some antifungals, such as ketoconazole or itraconazole
anti-proteases, medicines used to treat HIV infection, such as ritonavir
simvastatin, a medicine used to lower cholesterol
cyclosporin tacrolimus, sirolimus or everolimus, medicines used to suppress the immune
St John's Wort.
Your doctor and pharmacist have more information on medicines to be careful with or
avoid while taking Norvasc.
How to take Norvasc
Take Norvasc exactly as your doctor has prescribed.
Follow all directions given to you by your doctor or pharmacist carefully.
They may differ from the information contained in this leaflet.
If you do not understand the instructions on the box, ask your doctor or pharmacist
How much to take
The usual dose of Norvasc is 5 mg each day. Your doctor may increase this to 10 mg
Your doctor may prescribe another dose of Norvasc depending on your condition and
how you respond to this medicine.
How to take it
Swallow the tablet whole with a full glass of water.
When to take it
Take your medicine at about the same time each day, either morning or evening.
Taking it at the same time each day will have the best effect. It will also help you
remember when to take it.
Norvasc can be taken with or without food.
How long to take it
You must take Norvasc every day. Continue taking your medicine for as long as your
doctor tells you.
This medicine helps to control your condition, but does not cure it. It is important
to keep taking your medicine even if you feel well.
If you forget to take it
If it is less than 12 hours before your next dose, skip the dose you missed and take
your next dose when you are meant to.
Otherwise, take it as soon as you remember, and then go back to taking your medicine
as you would normally.
Do not take a double dose to make up for the dose that you missed.
This may increase the chance of you getting an unwanted side effect.
If you are not sure what to do, ask your doctor or pharmacist.
If you have trouble remembering to take your medicine, ask your pharmacist for some
If you take too much (overdose)
Immediately telephone your doctor or Poisons Information Centre - the telephone number
in Australia is 131 126 and in New Zealand is 0800 POISON or 0800 764 766 - for advice
or go to Accident and Emergency at your nearest hospital if you think that you or
anyone else may have taken too much Norvasc.
Do this even if there are no signs of discomfort or poisoning.
You may need urgent medical attention.
If you take too many tablets, you may feel dizzy, lightheaded or faint and have an
While you are taking Norvasc
Things you must do
Tell any other doctors, dentists and pharmacists who are treating you that you are
If you are about to start any new medicine, tell your doctor or pharmacist that you
are taking Norvasc.
If you become pregnant while taking Norvasc, tell your doctor immediately.
Keep all of your doctor's appointments so that your progress can be checked.
Your doctor may do some tests from time to time to make sure the medicine is working
and to prevent unwanted side effects.
Things you must not do
Do not take Norvasc to treat any other conditions unless your doctor tells you to.
Do not give this medicine to anyone else, even if they have the same condition as
Things to be careful of
Avoid eating large quantities of grapefruit or drinking large quantities of grapefruit
Grapefruit juice contains one or more components that alter the metabolism of some
medicines, including Norvasc.
Drinking very large quantities (over 1.2 litres) of grapefruit juice each day while
taking Norvasc may increase the effects of this medicine.
Be careful driving or operating machinery until you know how Norvasc affects you.
Norvasc may cause dizziness or drowsiness in some people.
If you have any of these symptoms, do not drive, operate machinery or do anything
else that could be dangerous.
Things that would be helpful for your high blood pressure or angina
Some self-help measures suggested below may assist your condition. Your doctor or
pharmacist can give you more information about these measures.
Weight: Your doctor may suggest losing some weight. Some people may need a dietician
to plan a suitable diet to help with weight loss.
Exercise: Regular exercise helps lower blood pressure and strengthen the heart. It
is important not to overdo it. Before commencing regular exercise you should consult
your doctor who will suggest the most suitable exercise for you. If you feel uncomfortable
when exercising or experience symptoms such as chest pain or breathlessness see your
Alcohol: Your doctor may advise you to limit your alcohol intake.
Salt: Your doctor may advise you to watch the amount of salt in your diet. To reduce
your salt intake you should avoid using salt at the table or in cooking.
Smoking: Your doctor may advise you to stop smoking or at least cut down.
Tell your doctor or pharmacist as soon as possible if you do not feel well while you
are taking Norvasc.
Norvasc helps most people but it may have some unwanted side effects in a few people.
All medicines can have side effects. Sometimes they are serious, most of the time
they are not. You may need medical attention if you get some of the side effects.
It can be difficult to tell whether side effects are the result of taking Norvasc,
effects of your condition or side effects of other medicines you may be taking. For
this reason it is important to tell your doctor of any change in your condition.
Do not be alarmed by the list of possible side effects.
You may not experience any of them.
Tell your doctor if...
Ask your doctor or pharmacist for advice if you experience any of the following and
they worry you:
drowsiness or sleepiness
stomach pain or nausea.
These are the more common side effects of Norvasc. All side effects should be reported
to a health professional.
Tell your doctor or pharmacist if you experience any of the following and they worry
These may or may not be due to Norvasc but you should tell your doctor.
Tell your doctor as soon as possible if...
Tell your doctor immediately if you notice any of the following:
changes in heart beat either fast or slow
swelling of the ankles, feet, face or hands
tingling or numbness of the hands or feet
dizziness or lightheadedness on standing up from a sitting or lying position
unusual tiredness or weakness
muscle cramps or aches
eye pain or change in vision
changes in mood, feeling anxious or nervous
symptoms of liver disease such as itching, yellowing of the skin and eyes, and dark
unusual movements, including trembling and shaking of the hands and fingers, twisting
movements of the body, shuffling walk and stiffness of the arms and legs.
These may be serious side effects that may need urgent medical attention
Go to hospital if...
Tell your doctor immediately or go to Accident and Emergency at your nearest hospital,
if you notice any of the following:
fast or irregular heart beats
chest pain associated with exertion (angina) that lasts longer, is more severe or
occurs more often
shortness of breath
symptoms of allergy such as skin rash and/or itching
severe upper stomach pain, often with nausea and vomiting.
The above list includes very serious side effects. You may need urgent medical attention
Ask your doctor or pharmacist to answer any questions you may have.
If you are 65 years or older, you should be especially careful while taking Norvasc.
Report any side effects promptly to your doctor.
Some people in this age group may be more likely to experience side effects such as
swelling of the feet and ankles, muscle cramps and dizziness.
Tell your doctor or pharmacist if you notice anything else that is making you feel
Other side effects not listed above may also occur in some people.
After taking Norvasc
Keep your tablets in the pack until it is time to take them.
If you take your tablets out of the pack they may not keep as well.
Keep your tablets in a cool dry place where the temperature stays below 25°C.
Do not store Norvasc or any other medicine in the bathroom or near a sink. Do not
leave your medicines on a window sill or in the car.
Heat and dampness can destroy some medicines.
Keep Norvasc where children cannot reach it.
A locked cupboard at least one-and-a-half metres above the ground is a good place
to store medicines.
If your doctor tells you to stop taking Norvasc, or the tablets have passed their
expiry date, ask your pharmacist what to do with any medicine that is left over.
What it looks like
Norvasc tablets are available in two strengths:
Norvasc 5 mg tablets: emerald-shaped, white to off-white, scored and marked NVC/5
on one side and Pfizer on the other, or engraved "AML 5" and breaker score on one
side and "Pfizer" logo on the other side.
Norvasc 10 mg tablets: emerald-shaped, white to off-white, scored and marked NVC/10
on one side and Pfizer on the other, or engraved "AML-10" on one side and "Pfizer"
logo on the other side.
Both the 5 mg tablets and 10 tablets come in packs of 30 tablets.
Norvasc 5 mg tablets contain amlodipine besilate equivalent to amlodipine 5 mg.
Norvasc 10 mg tablets contain amlodipine besilate equivalent to amlodipine 10 mg.
calcium hydrogen phosphate
sodium starch glycollate
Norvasc does not contain gluten, sugar or lactose.
Norvasc is supplied in Australia by:
Pfizer Australia Pty Ltd
ABN 5000 8422 348
38-42 Wharf Road
West Ryde NSW 2114
Toll Free Number: 1800 675 229
Norvasc is supplied in New Zealand by:
Pfizer New Zealand Limited
PO Box 3998
Auckland, New Zealand
Toll Free Number: 0800 736 363
Australian Registration Numbers:
Norvasc 5 mg - AUST R 42902
Norvasc 10 mg - AUST R 42903
This leaflet was prepared in May 2018.
® = Registered Trademark
© Pfizer Australia Pty Ltd 2018