Che cosa è Hyperinsulinemia?

Hyperinsulinemia descrive un livello aumentato di insulina nel sangue. La circostanza è associata con intolleranza al glucosio, l'obesità, l'ipertensione e la dislipidemia, fattori che si riferiscono a collettivamente come la sindrome metabolica.

Hyperinsulinemia è distinto sia dal diabete o dall'iperglicemia, ma si presenta come conseguenza del diabete della fase iniziale, che può diventare il diabete se non è trattato correttamente.

Hyperinsulinemia piombo a parecchie circostanze e questi sono descritti qui sotto.

  • Ipoglicemia o zucchero di sangue basso
  • Diabete o zucchero di sangue incontrollato che oscilla fra un minimo ed ad alto livello
  • Rischio aumentato di sindrome ovarica policistica (PCOS)
  • Produzione aumentata delle lipoproteine molto a bassa densità (VLDLs), citata come hypertriglyceridemia.
  • Rischio aumentato di cardiovascolare o di malattia di cuore
  • Coronaropatia - il livello elevato dell'insulina nuoce alle celle endoteliali che allineano le arterie coronarie.
  • Ipertensione o ipertensione
  • Ghiandola tiroide Underactive
  • Obesità e letargia

Cause

L'insulino-resistenza è la causa primaria del hyperinsulinemia. Quando una persona ha insulino-resistenza, il pancreas prova a compensare producendo più insulina. Ciò può piombo al diabete di tipo 2, che accade quando il pancreas non riesce a produrre abbastanza insulina per regolamentare adeguatamente la glicemia. In rari casi, un tumore pancreatico può causare il hyperinsulinemia. Una circostanza ha chiamato il nesidioblastosis, dove c'è un eccesso delle celle che producono l'insulina nel pancreas possono anche piombo al hyperinsulinemia.

Sorgenti

  1. http://diabetes.diabetesjournals.org/content/61/1/4.full.pdf
  2. http://sur1.congenitalhi.org/Kenneth.pdf
  3. http://www.diabetes.co.uk/hyperinsulinemia.html
  4. http://www.gosh.nhs.uk/medical-information/search-for-medical-conditions/hyperinsulinism/hyperinsulinism-information/
  5. http://www.rdehospital.nhs.uk/prof/molecular_genetics/tests/Hyperinsulinism.html

Further Reading

Last Updated: Feb 26, 2019

Dr. Ananya Mandal

Written by

Dr. Ananya Mandal

Dr. Ananya Mandal is a doctor by profession, lecturer by vocation and a medical writer by passion. She specialized in Clinical Pharmacology after her bachelor's (MBBS). For her, health communication is not just writing complicated reviews for professionals but making medical knowledge understandable and available to the general public as well.

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Comments

  1. constanza constanza constanza constanza Argentina says:

    Hola,en mi apinion creo que esta pesimo que una pagina como esta ponga que la hieperinsulinemia es tambien conocida como pre-diabetes,ya que eso es mentira!,la hiperinsulinemia se debe a muchos factores que a veces no se relacionan ni por cerca a una pre-diabetes

  2. Gary Turner Gary Turner United States says:

    Hyperinsulinemia is best treated by removing the foods from your diet that cause an insulin spike and replace them with high quality fats. Remove all sugars, fruit juices, pop, and starches and all liquid vegetable and seed oils, especially hydrogenated versions. Replace these foods with olives, avocados, coconuts, and their oils. Also raw tree nuts, fish and fish oils. Get adequate protein and eat lots of on starchy raw vegetables.

    • Dale Just-Dale Dale Just-Dale United States says:

      This is good advice for those who have a genetic predisposition for diabetes.   Unfortunately, eating a healthy diet does little to change your genetic makeup.   An extremely strict diet will keep your weight down, exercise will increase your insulin sensitivity.  The latest research on metabolic memory however indicates that extremely aggressive treatment of this condition makes a huge difference down the road.  Unfortunately for most, when this is discovered, they have already had over an 80% reduction of their beta-cell mass, leading to elevated glucagon levels and increased liver production of glucose from glycogen.   Strict diet tremendously helps, but you cannot get your beta cells back (for the most part).   People who discover this early, and treat aggressively with diet, exercise and treatment with insulin-sensitizing medication can have a normal life-span. (See research on metabolic memory)

  3. Gary Turner Gary Turner United States says:

    Eat lots of non starchy vegetables

The opinions expressed here are the views of the writer and do not necessarily reflect the views and opinions of News-Medical.Net.
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