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  • Flow Cytometry Techniques used in Medicine and Research
    Life Sciences - 28 Jun 2019
    This article describes the combination of flow cytometry with other techniques and the applications of these techniques in medicine and research.
  • Pharmacology of CAR-T Cells
    Life Sciences - 26 Feb 2019
    Chimeric antigen receptor (CAR)-T cells are T cells which are genetically modified by the addition of tumor-reactive chimeric antigen receptors (CARs). The T cells are the workhorses of the immune...
  • What is Necroptosis?
    Life Sciences - 26 Feb 2019
    Initially, cell death was believed to be either programmed, called “apoptosis”, or passive, called “necrosis”. Apoptosis was considered instrumental to development and other physiological functions,...
  • Missing Self Hypothesis for Natural Killer Cells
    Life Sciences - 26 Feb 2019
    Natural killer cells are an integral part of the human immune system, representing the front line of defence against tumor-forming cells and pathogens. These cells utilise several different methods to...
  • Quorum Sensing and Pseudomonas aeruginosa
    Life Sciences - 26 Feb 2019
    One of the ways P. aeruginosa causes infection is through quorum sensing; a type of cell signalling pathway that initiates the production of virulence factors.
  • The IDO Pathway
    Life Sciences - 26 Feb 2019
    The enzyme Indoleamine 2,3 dioxygenase (IDO) is part of a metabolic pathway involved in inflammation.
  • Temperate Bacteriophages and the Lysogenic Cycle
    Life Sciences - 24 Jan 2019
    Temperate bacteriophages display a lysogenic life cycle, which requires them to integrate their viral genome into the bacterial chromosome.
  • Using Fluorescence Microscopy to Study Proteins
    Life Sciences - 28 Nov 2018
    Fluorescence microscopy can be used visualize proteins inside live cells. This is particularly useful when studying signaling pathways and binding partners.
  • Macrophage to Foam Cell Differentiation Pathway
    Life Sciences - 29 Oct 2018
    Macrophages differentiate into foam cells during the formation and progression of atherosclerosis. Understanding the process of this change during the progression of atherosclerotic plaques will allow...
  • Tyramide Signal Amplification (TSA) Applications
    Life Sciences - 18 Oct 2018
    Tyramide signal amplification (TSA) is a biological technique used to detect proteins, DNA, and viruses. It can be combined with other techniques such as FISH.

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