Estrogen drives gut pain and explains higher rates of IBS in women

	Women's Health
	The latest women's health news from News Medical

	Estrogen drives gut pain and explains higher rates of IBS in women Women are dramatically more likely than men to suffer from irritable bowel syndrome (IBS), a chronic condition causing abdominal pain, bloating, and digestive discomfort.

	Cutting carbs, not fat, may better control appetite in women Research indicates low-carb diets may enhance appetite regulation and reduce food cues in women with lipedema, offering a dietary intervention advantage.

	Blood metabolite profiling outperforms BMI in predicting pregnancy complications This study shows that a blood-based metabolomic signature linked to maternal BMI predicts gestational diabetes and preeclampsia more strongly than BMI alone, particularly in late pregnancy. A subset of 16 metabolites statistically mediates the BMI–gestational diabetes association, highlighting metabolic pathways that may improve prenatal risk stratification.

	Many women suffer in silence from treatable pelvic floor conditions Many women assume pelvic floor health issues are simply their fate—part of having vaginal deliveries, getting older, gaining weight or entering menopause. Perhaps they have watched their mothers and grandmothers live with symptoms, such as urinary incontinence and pain.

	World Health Organization validates Brazil's elimination of mother-to-child HIV transmission The World Health Organization (WHO) has validated Brazil for the elimination of mother-to-child transmission (EMTCT) of HIV, making it the most populous country in the Americas to achieve this historic milestone.

			HPV vaccination reduces risk of vulvar and vaginal lesions Girls who are vaccinated against HPV are not only well protected against cervical cancer; they are also less likely to develop severe precancerous lesions of the vulva and vagina, particularly if they were vaccinated before the age of 17.

			Menopause hormone therapy not linked to dementia risk in women A major review of prior research has found no evidence that menopause hormone therapy either increases or decreases dementia risk in post-menopausal women, in a new study led by University College London (UCL) researchers.

			Gestational diabetes alters the placenta at the molecular level, study reveals Gestational diabetes can cause a multitude of complications in the offspring, but to date, the reasons are incompletely understood.

			New ultrasound method accurately distinguishes fluid from solid breast masses New ultrasound technology developed at Johns Hopkins can distinguish fluid from solid breast masses with near perfect accuracy, an advance that could save patients, especially those with dense breast tissue, from unnecessary follow-up exams, painful procedures and anxiety.

	Simple blood test maps hidden Alzheimer’s disease changes This population-based study used plasma pTau217 to estimate how common Alzheimer’s disease neuropathological changes are across age and cognitive status in a Norwegian community cohort. Prevalence rose steeply with age and was strongly associated with APOE ε4 genotype, education level, and kidney function, with implications for future use of blood biomarkers in clinical practice.

	Whooping cough cases rise sharply across the United States Pertussis, also known as whooping cough, is a vaccination-preventable illness that has been on the rise in the United States. Following a several-year lull during the pandemic, cases of whooping cough rose sixfold in 2024 and remain high.

	Intermittent fasting edges daily calorie cuts for blood pressure and long-term cardiovascular risk estimates In a real-world registry study of adults with overweight or obesity, 5:2 intermittent fasting and daily calorie restriction both improved blood pressure over 12 weeks. Intermittent fasting produced modestly greater reductions in systolic and pulse pressure and a larger drop in BMI-based 30-year cardiovascular risk scores, without superior lipid or glycaemic effects.

	Plant-based omega-3s work better than expected in a year-long diet study A year-long, diet-controlled intervention shows that flaxseed oil–derived alpha-linolenic acid significantly increases erythrocyte EPA, DPA, and DHA across omnivorous, vegetarian, and vegan diets. The magnitude of improvement is driven mainly by baseline omega-3 status, while absolute EPA and DHA levels in vegans remain lower than in omnivores.

	Genes and biological networks that drive long COVID risk This study merges causal genetics and network theory, revealing 32 genes linked to long COVID, offering insights for diagnostics and personalized therapies.

	Getting a dog for the first time boosts walking and remote social ties First-time dog owners in Japan showed significant increases in walking activity and non-face-to-face social contact over one year compared with non-dog owners. No significant changes were observed in vigorous activity or face-to-face social contact, highlighting specific behavioral associations rather than broad lifestyle shifts.

	Everyday light exposure shapes how alert and mentally sharp we feel outside the lab This real-world study shows that recent and habitual light exposure are linked to lower subjective sleepiness and faster reaction times in daily life. Brighter and more stable daytime light patterns were associated with better performance on specific cognitive tasks, independent of sleep and time of day.

	Social isolation emerges as a key, independent risk factor for cognitive decline Using longitudinal data from the US Health and Retirement Study, this study applied causal inference modeling to disentangle the independent and joint effects of social isolation and loneliness on later-life cognitive function. It shows that reducing social isolation is associated with modest but meaningful protection against cognitive decline, with loneliness mediating only a small proportion of this effect.

	Fertility preferences remain high in rural Tanzania despite family planning access Fertility rates in much of Sub-Saharan Africa remain high, despite declining child mortality and improved access to contraceptives and female education - factors that generally lead to smaller families and improved economic conditions in developing countries.

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