Fertility treatments linked to small increases in some cancers

	Women's Health
	The latest women's health news from News Medical

	Fertility treatments linked to small increases in some cancers Findings indicate small increases in certain cancers linked to assisted reproduction, though overall cancer incidence aligns with the general female population.

	Eating earlier in the day is linked to lower nighttime glucose in gestational diabetes A secondary analysis of a randomized trial examined whether the timing of the first daily meal affects 24-hour glucose patterns in pregnancies with gestational diabetes. Earlier first meals were associated with lower nocturnal glucose levels and an earlier daily glucose rhythm, although overall glycaemic control metrics were similar between groups.

	Training game helps nurses spot fungal infections in breastfeeding This educational game simulates breastfeeding complications, equipping nurses with skills to detect and manage fungal infections in the nipple-areola area.

	Blood test marker p-tau217 helps detect early dementia risk in cognitively healthy older women A long-term study of 2,766 women in the Women’s Health Initiative Memory Study found that higher baseline plasma p-tau217 levels were associated with a greater risk of developing mild cognitive impairment or probable dementia.

			VALANX Biotech secures €3 million to advance LIV-1 ADC for metastatic triple-negative breast cancer VALANX Biotech (VALANX), a biotech company developing a technology for site-selectable, site-specific protein conjugation, today announced it has secured €3 million to advance its lead antibody-drug conjugate (ADC) program.

			Vaginal microbiome may play key role in pregnancy health and preterm birth risk, researchers say Researchers reviewed evidence linking the vaginal microbiome to pregnancy health and spontaneous preterm birth, highlighting how Lactobacillus-dominated communities help maintain immune balance and vaginal acidity. Dysbiosis and inflammatory signaling may contribute to preterm birth risk, while emerging microbiome-targeted therapies aim to restore protective microbial ecosystems.

			Global study reveals how inequality limits access to exercise and why it matters for health A global analysis of physical activity data from 68 countries shows large socioeconomic and gender inequalities in access to choice-based exercise, particularly active leisure. The study also synthesizes evidence linking physical activity to lower risks of severe infectious disease, depression, and cancer mortality, and proposes a new “physical activity for health and wellbeing” public health framework.

			Why do some people respond better to GLP-1 drugs? Gut microbiome may hold clues A review in the Canadian Journal of Physiology and Pharmacology examines emerging evidence linking glucagon-like peptide-1 receptor agonists (GLP-1 RAs), the gut microbiome, and obesity treatment outcomes. The authors conclude that microbiome changes seen during therapy are most likely driven by diet, behavior, and weight loss, although microbial profiling may eventually help predict patient responses.

	Does coffee disrupt sleep? Large population study suggests the impact may be minimal A large cross-sectional analysis of 25,381 Swedish adults aged 50–64 found that habitual coffee consumption showed only very weak associations with sleep quality and daytime sleepiness. Genetic analyses confirmed known coffee-related variants and suggested that long-term caffeine exposure may lead to adaptation in the brain’s adenosine signaling system.

	Study reveals why US life expectancy gains stalled after decades of progress A PNAS study analyzing US mortality from 1979 to 2023 reveals that life expectancy stagnation reflects both worsening outcomes in post-1950 birth cohorts and a broad mortality deterioration beginning around 2010. Cardiovascular mortality slowdowns, rising external causes, and cohort-specific patterns help explain the persistent decline in longevity gains.

	Swapping red meat for plant-based meat rapidly lowers a key heart risk metabolite, trial finds A randomized crossover trial found that replacing red meat patties with processed plant-based meat alternatives for six days significantly lowered circulating trimethylamine N-oxide (TMAO), a gut-derived metabolite linked to cardiovascular risk. The plant-based phase also produced modest reductions in cholesterol markers but slightly increased weight and NT-proBNP, possibly due to higher sodium intake.

	U.S. cigarette smoking falls below 10% for the first time but millions still use tobacco Analysis of the 2023–2024 National Health Interview Survey shows that 18.8% of U.S. adults use tobacco, while cigarette smoking has fallen to 9.9%, the first time it has dropped below 10% nationally. Despite this milestone, millions of Americans still use cigars, e-cigarettes, or smokeless tobacco, with notable disparities across age, income, occupation, and geography.

	Patients who stop GLP-1 drugs often restart or try alternatives The study highlights that after stopping GLP-1 medications, many patients resume treatment or try alternatives, influencing weight management strategies.

	Could a simple milk habit help prevent strokes? New research points to potential benefits A modeling study in Nutrients projected that raising average milk consumption in Japan to recommended levels could reduce stroke incidence, stroke mortality, and healthcare spending over 10 years. The analysis suggests that modest dietary changes, particularly increased milk intake, may produce measurable population-level health and economic benefits.

	Maternal antibodies protect newborns from severe E. coli infections, study finds A multi-center study led by researchers at Cincinnati Children's sheds surprising new light on why some newborns become severely ill from Escherichia coli infection, but others do not.

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