| |  An individualized neoantigen mRNA vaccine was tested in patients with early-stage triple-negative breast cancer and showed feasibility, safety, and strong T cell immune responses. Long-term follow-up suggested durable immune memory with encouraging relapse-free outcomes, though controlled trials are needed to confirm clinical benefit. | |
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| |  A phase IIa randomized trial found that intravenous dimethyltryptamine (DMT) with structured psychological support produced rapid reductions in depressive symptoms in adults with major depressive disorder. Improvements were statistically significant versus placebo at two weeks, with mostly mild-to-moderate adverse events and the need for larger confirmatory studies emphasized. | |
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| |  Higher grip strength in older women correlates with lower all-cause mortality, underscoring the need for muscle-strengthening activities in public health. | |
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| |  This systematic review in Nutrients evaluates human studies investigating whether polyphenol-rich berry consumption can modulate obesity-related metabolic dysfunction and support cognitive performance, particularly in individuals at risk of mild cognitive impairment. Evidence suggests modest memory benefits and possible metabolic improvements, although biomarker findings and long-term clinical relevance remain uncertain. | |
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| |  A single exposure to a toxic fungicide during pregnancy can increase the risk of disease for 20 subsequent generations - with inherited health problems worsening many generations after exposure. | |
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| |  Researchers at Amsterdam UMC have discovered that a second pregnancy alters the female brain. Previous research from the same group had already demonstrated the impact of a first pregnancy on the female brain. | |
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| |  You don't need to look like a bodybuilder, but for healthy aging, maintaining muscle strength is likely just as important as getting enough aerobic activity. | |
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| |  Emerging evidence suggests nanoplastics accumulate in human tissues including the brain and may contribute to neuroinflammation and neurodegenerative disease pathways. However, causality, exposure routes, and long-term health effects remain uncertain and require coordinated research. | |
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| |  This study identifies IFN-γ as a crucial blood-based biomarker for Alzheimer's, revealing its role in microglial inflammation and genetic risk interactions. | |
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| |  Early detection and prompt treatment of acute pulmonary embolism (PE), a sudden and potentially life-threatening blood clot that blocks arteries in the lungs, is critical. | |
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| |  A new multinational study from the INTERCOVID Consortium, including Ann & Robert H. Lurie Children's Hospital of Chicago, has found that COVID-19 vaccination during pregnancy, particularly when combined with a booster dose, significantly reduces the risk of preeclampsia, a serious and potentially life-threatening pregnancy complication. | |
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| |  Coronary artery disease (CAD) is the most common cause of death globally. In CAD, plaques composed of cholesterol, fats, calcium and other compounds accumulate and create obstructions in the coronary vessels that supply blood to the heart. | |
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| |  Grip strength correlates with working memory performance and prefrontal activation, highlighting its potential as a cognitive health marker in older adults. | |
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| |  The Massage Therapy Foundation (MTF) announces the award of a research grant to University of Denver, Denver, Colo. The grant will support a three-year study entitled, "Prenatal Massage: A Complementary Approach for Maternal Health and Mental Health," led by Primary Investigator Galena Rhoades, PhD. | |
