Researchers reveal why SuperAgers retain youthful brain cell signatures into their 80s
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 Higher tyrosine levels linked to shorter lifespan in major UK Biobank analysisHigher tyrosine levels linked to shorter lifespan in major UK Biobank analysis
 
Researchers analyzed over 272,000 UK Biobank participants and used Mendelian randomization to investigate whether circulating phenylalanine and tyrosine influence lifespan. Genetically predicted higher tyrosine levels were linked to shorter lifespan, particularly in men, while phenylalanine showed no independent effect after adjustment.
 
 
 Researchers reveal why SuperAgers retain youthful brain cell signatures into their 80sResearchers reveal why SuperAgers retain youthful brain cell signatures into their 80s
 
Researchers used single-nucleus RNA sequencing and chromatin accessibility profiling to map human hippocampal neurogenesis across adulthood, aging, and Alzheimer’s disease. They found that chromatin accessibility changes, more than gene expression alone, distinguish healthy aging, preclinical pathology, Alzheimer’s disease, and cognitive resilience in SuperAgers.
 
   Living near nuclear power plants is associated with higher cancer mortality, national US study reportsLiving near nuclear power plants is associated with higher cancer mortality, national US study reports
 
A nationwide ecological study of US counties from 2000 to 2018 found that greater proximity to operational nuclear power plants was associated with higher cancer mortality rates, particularly among adults aged 65–74 years. The analysis used inverse-distance weighting within 200 km and adjusted for demographic, socioeconomic, environmental, and healthcare factors, but did not measure individual radiation exposure.
 
   Heavy alcohol intake is associated with dangerous belly fat accumulation, large UK study showsHeavy alcohol intake is associated with dangerous belly fat accumulation, large UK study shows
 
In a large UK population cohort, higher weekly alcohol consumption was dose-dependently associated with greater visceral fat mass measured by DXA, independent of total body fat. Heavy drinkers showed over 10% higher proportional visceral fat compared with lower consumption groups, a pattern linked to increased cardiometabolic risk.
 
   Can brain training prevent dementia? Long-term trial shows speed training with boosters makes a differenceCan brain training prevent dementia? Long-term trial shows speed training with boosters makes a difference
 
A 20-year follow-up of older adults in the ACTIVE randomized trial linked to Medicare claims found that speed of processing cognitive training with booster sessions was associated with a significantly lower risk of diagnosed Alzheimer’s disease and related dementias. Memory and reasoning training did not show comparable long-term reductions in dementia risk.
 
 Having “hasslers” in your network linked to faster aging and poorer health
 
Having “hasslers” in your network linked to faster aging and poorer healthResearchers analyzed a state-representative US sample to examine whether negative social ties, termed “hasslers,” are associated with epigenetic age acceleration and faster biological aging. Each additional hassler was linked to roughly nine months higher biological age and a 1.5% faster pace of aging, with particularly strong associations for mental health outcomes.
 
 
 Study reveals knowledge gaps about menstrual health in elite women’s football
 
Study reveals knowledge gaps about menstrual health in elite women’s footballElite European women’s football players and staff show substantial knowledge gaps about menstrual health and hormonal contraception despite widespread openness to discussion. The study highlights the need for structured education to support informed health decisions while clarifying that perceived performance effects are not consistently supported by scientific evidence.
 
 
 Could a rare gene variant help reduce smoking? New study suggests it might
 
Could a rare gene variant help reduce smoking? New study suggests it mightAn exome-wide association study of nearly 38,000 smokers from the Mexico City Prospective Study identified rare coding variants in CHRNB3 that are associated with substantially fewer cigarettes smoked per day. Cross-ancestry analyses in European and East Asian datasets support a role for the β3 nicotinic receptor subunit in modulating smoking intensity.
 
 
 Ultraprocessed foods are engineered like cigarettes
 
Ultraprocessed foods are engineered like cigarettesThe parallels between ultraprocessed foods and tobacco raise concerns about addiction and health risks, urging policymakers to implement effective regulations.
 
 
 Heart attack deaths increase in young adults, especially women
 
A new study found that heart attack deaths were up among younger adults with women more likely than men to die after a first heart attack.
 
 
 Fiber intake may reduce heart disease risk in night shift workers
 
Fiber intake may reduce heart disease risk in night shift workersResearch shows higher fiber consumption may lower coronary heart disease risk in night shift workers, suggesting dietary adjustments for better health.
 
 
 Exercise during chemotherapy boosts breast cancer patients' quality of life
 
Exercise during chemotherapy boosts breast cancer patients' quality of lifeFor many women with breast cancer, the very treatment that saves their lives can also bring fatigue, loss of muscle mass, emotional strain and other daunting obstacles.
 
 
 Nearly 6 in 10 women in the U.S. may have cardiovascular disease in the next 25 years
 
Driven by rising rates in high blood pressure, nearly 6 in 10 women in the U.S. will have some type of cardiovascular disease (CVD) in the next 25 years, according to a new scientific statement published today in Circulation, the peer-reviewed, flagship journal of the American Heart Association, a global force changing the future of health for all.
 
 
 HIT cell therapy eradicates solid tumors in preclinical models
 
CAR T cell therapy has revolutionized the treatment of many blood cancers, but has shown little success against solid tumors, which account for over 85% of all cancers.
 
 
 US measles and pertussis outbreaks expose policy failures, not just vaccine hesitancy
 
US measles and pertussis outbreaks expose policy failures, not just vaccine hesitancyA recent commentary argues that US measles and pertussis outbreaks are not simply the result of vaccine hesitancy but reflect weakened immunization policies, permissive exemptions, and underfunded public health systems. The authors contend that policy environments determine whether pockets of low coverage escalate into large-scale, preventable outbreaks.
 
 
 Study confirms long-term effectiveness of HPV vaccination
 
Study confirms long-term effectiveness of HPV vaccinationHuman papillomavirus (HPV) vaccination is associated with a significantly reduced risk of invasive cervical cancer, with no indication of waning protection up to 18 years after vaccination, finds a study from Sweden published by The BMJ today.
 
 
 Global breast cancer burden rising fastest in low-income countries
 
Global breast cancer burden rising fastest in low-income countriesDespite recent advancements in breast cancer treatments, new breast cancer cases in women are predicted to rise by a third globally from 2.3 million in 2023 to more than 3.5 million in 2050.
 
 
 FDA clears cloud-based AI system to forecast predicted delivery date
 
FDA clears cloud-based AI system to forecast predicted delivery dateUltrasound AI, a pioneer in artificial intelligence applications for medical imaging, today announced it has received FDA De Novo clearance for its flagship Delivery Date AI technology, a cloud-based SaMD that determines a Predicted Delivery Date (PDD) solely from standard ultrasound images and seamless integration into current OB/MFM prenatal visit workflows; PDD is provided in real-time for actionable decision-making by the clinical team.
 
 
 Denmark achieves historic elimination of mother-to-child HIV and syphilis transmission
 
Denmark achieves historic elimination of mother-to-child HIV and syphilis transmissionThe World Health Organization (WHO) has certified Denmark for the elimination of mother-to-child transmission (EMTCT) of HIV and syphilis, recognizing the country's sustained commitment to ensuring every child is born free of these infections.
 
 
 Living in deprived neighborhoods reshapes the gut microbiome
 
Living in deprived neighborhoods reshapes the gut microbiomeThis study reveals links between socioeconomic deprivation and gut microbiome changes, highlighting potential pathways to mental and metabolic health issues.
 
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