Three daily servings of full-fat dairy do not worsen weight or blood markers
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 Why exercise is essential for restoring fitness after GLP-1-based weight lossWhy exercise is essential for restoring fitness after GLP-1-based weight loss
 
This randomized controlled trial shows that structured moderate-to-vigorous exercise, alone or combined with liraglutide, improves physical function and cardiorespiratory fitness after diet-induced weight loss in adults with obesity. In contrast, liraglutide alone sustains weight loss but does not significantly improve measured physical fitness outcomes.
 
 
 Three daily servings of full-fat dairy do not worsen weight or blood markersThree daily servings of full-fat dairy do not worsen weight or blood markers
 
This randomized 12-week trial examined whether adding three daily servings of full-fat dairy to diets aligned with Canada’s Food Guide affects body weight, cardiometabolic markers, and nutrient intake in adults with overweight or obesity. Full-fat dairy intake did not adversely affect weight, body composition, or metabolic health and increased calcium and protein intake, supporting dietary compatibility rather than therapeutic benefit.
 
   How modern lifestyles reprogram the gut microbiome and shape disease riskHow modern lifestyles reprogram the gut microbiome and shape disease risk
 
Modern lifestyle factors such as circadian disruption, sleep deprivation, stress, and exercise reshape the gut bacteriome and its metabolic outputs. These microbiome changes are linked to immune, metabolic, and cancer-related pathways, largely through evidence from animal models and observational human studies.
 
   When you eat matters: early time-restricted eating improves metabolic healthWhen you eat matters: early time-restricted eating improves metabolic health
 
Time-restricted eating improves several metabolic outcomes compared with usual diets, with benefits observed for body weight, adiposity, blood pressure, insulin, glucose, and triglycerides. Early eating windows consistently outperform late eating, while the optimal duration of food intake remains uncertain.
 
   Nearly half of adults now live with heart disease as obesity and diabetes surgeNearly half of adults now live with heart disease as obesity and diabetes surge
 
The 2026 American Heart Association Heart Disease and Stroke Statistics report shows that nearly half of adults are living with cardiovascular disease, with cardiometabolic risk factors projected to rise substantially by 2050. Despite progress in smoking reduction and cholesterol control, worsening obesity, diabetes, hypertension, sleep health, and persistent inequities threaten future cardiovascular health.
 
 Regular aerobic exercise slows a key marker of brain aging in midlife
 
Regular aerobic exercise slows a key marker of brain aging in midlifeRegular aerobic activity significantly reduces brain-PAD, indicating that exercise is crucial for maintaining brain health and reducing dementia risk.
 
 
 Exercise variety, not just volume, is tied to longer life
 
Exercise variety, not just volume, is tied to longer lifeResearchers analysed nearly three decades of data from more than 111,000 adults to examine whether the variety of physical activities people perform is linked to long-term survival. They found that engaging in a broader range of activity types was associated with lower all-cause mortality, independent of total exercise volume.
 
 
 Why eating more oats can rapidly reduce cholesterol levels
 
Why eating more oats can rapidly reduce cholesterol levelsOat consumption boosts gut microbiota-derived phenolic metabolites, driving cholesterol-lowering effects and improving lipid metabolism in metabolic syndrome.
 
 
 Reducing alcohol consumption could significantly lower cancer deaths
 
Reducing alcohol consumption could significantly lower cancer deathsReducing annual alcohol consumption in Australia by one litre a person could significantly lower deaths from several major cancers, particularly among older Australians, a new study led by La Trobe University has found.
 
 
 Ageing slows brain protein clearance and shifts synaptic waste to microglia
 
Ageing slows brain protein clearance and shifts synaptic waste to microgliaAgeing slows neuronal protein degradation in mice, leading to widespread accumulation and aggregation of long-lived proteins, particularly at synapses. As neuronal clearance declines, microglia selectively accumulate synaptic proteins, suggesting a compensatory but potentially strained proteostasis pathway in the ageing brain.
 
 
 Menopausal hormone therapy linked to greater weight loss with tirzepatide
 
Menopausal hormone therapy linked to greater weight loss with tirzepatideA new study led by Mayo Clinic found that postmenopausal women receiving menopausal hormone therapy lost 35% more weight while taking tirzepatide, a Food and Drug Administration-approved drug for the treatment of overweight and obesity.
 
 
 Following the EAT-Lancet diet lowers chronic kidney disease risk
 
Following the EAT-Lancet diet lowers chronic kidney disease riskResearch shows the EAT-Lancet diet may lower chronic kidney disease risk, emphasizing the importance of diet quality and personalized nutrition in prevention.
 
 
 Study identifies a powerful strategy to overcome drug resistance in breast cancer
 
Study identifies a powerful strategy to overcome drug resistance in breast cancerA new preclinical study from researchers at The University of Texas MD Anderson Cancer Center, published today in Nature Communications, identifies a powerful strategy to overcome drug resistance in breast cancer by simultaneously targeting two key cell-cycle regulators, CDK2 and CDK4/6.
 
 
 Genetic study links vitamin B1 metabolism to gut motility and IBS risk
 
Genetic study links vitamin B1 metabolism to gut motility and IBS riskResearch links thiamine metabolism to gut motility, identifying genetic markers that could lead to new therapies for IBS and related digestive disorders.
 
 
 A routine blood test may reveal who is most at risk of osteoporosis
 
A routine blood test may reveal who is most at risk of osteoporosisA routine creatinine blood test may identify individuals at higher risk for osteoporosis and fractures, highlighting its potential as a risk assessment tool.
 
 
 New medical LLM detects depression in women via WhatsApp audio analysis
 
New medical LLM detects depression in women via WhatsApp audio analysisA new medical large language model (LLM) achieved over 91 percent accuracy in identifying female participants diagnosed with major depressive disorder after analyzing a short WhatsApp audio recording where participants described their week, according to a study published January 21, 2026 in the open-access journal PLOS Mental Health by Victor H. O. Otani, from Santa Casa de São Paulo School of Medical Sciences and Infinity Doctors Inc.
 
 
 Olive oil type matters for cognition and gut health in older adults
 
Olive oil type matters for cognition and gut health in older adultsHigher intake of virgin and total olive oil was associated with modest but significant improvements in cognitive performance over two years in older adults with metabolic syndrome. These associations were partly linked to gut microbiota composition, with specific taxa such as Adlercreutzia contributing a small mediating effect.
 
 
 Wildfire smoke in late pregnancy may raise autism risk
 
Wildfire smoke in late pregnancy may raise autism riskPrenatal exposure to wildfire smoke in late pregnancy may modestly raise autism risk in children, emphasizing the importance of safeguarding pregnant women.
 
 
 Is fluoridated water safe during pregnancy? Studies say yes
 
Is fluoridated water safe during pregnancy? Studies say yesResearch analyzing 11.5 million births finds no association between community water fluoridation and reduced birth weight, ensuring prenatal safety.
 
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