A decades-long study raises questions about sugary drinks and stomach cancer
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 Women with type 2 diabetes saw striking changes after 24 weeks of this eating patternWomen with type 2 diabetes saw striking changes after 24 weeks of this eating pattern
 
A 24-week randomized trial found that a lacto-vegetarian diet combined with 14-hour time-restricted eating improved glycemic control, insulin resistance, body weight, and lipid measures in Indian women with type 2 diabetes. The combined, nutritionist-supported intervention was generally well tolerated, but its individual dietary and fasting effects cannot be separated and longer-term studies are needed.
 
 
 A decades-long study raises questions about sugary drinks and stomach cancerA decades-long study raises questions about sugary drinks and stomach cancer
 
A large prospective U.S. study followed more than 111,000 adults to examine whether sugar-sweetened and artificially sweetened beverage intake was associated with gastric cancer incidence. Researchers identified 278 gastric cancer cases over 3.2 million person-years and found that associations differed according to beverage type and level of consumption.
 
   What 3,600 adults with diabetes revealed about lifestyle and heart healthWhat 3,600 adults with diabetes revealed about lifestyle and heart health
 
In 3,612 British adults with type 2 diabetes, greater adherence to the Mediterranean Lifestyle Index was associated with lower risks of major adverse cardiovascular events, cardiovascular death, and all-cause mortality over more than a decade of follow-up. Dietary patterns, physical activity, rest, and social habits all contributed to the observed associations, although the observational study cannot establish causality.
 
   More coffee, higher testosterone? This study found a more complicated pictureMore coffee, higher testosterone? This study found a more complicated picture
 
Higher habitual coffee intake was associated with a leaner body composition, lower circulating branched-chain amino acids, and distinct cardiometabolic patterns in 2,264 middle-aged Finnish adults. Hormonal associations differed by sex, with broader testosterone- and SHBG-related patterns in men and more limited SHBG-related changes in women.
 
   A childhood shaped by sugar rationing was linked to mental health more than 50 years laterA childhood shaped by sugar rationing was linked to mental health more than 50 years later
 
UK Biobank researchers examined whether sugar rationing during pregnancy and the first two years of life was associated with adult sweet-food preferences, sugar intake, brain structure, anxiety, and depression.
 
 A striking immune cell pattern emerges around a person’s 100th birthday
 
A striking immune cell pattern emerges around a person’s 100th birthdaySingle-cell immune profiling found that CD4 cytotoxic T lymphocytes become more abundant around age 100, showing stepwise differentiation and substantial clonal expansion. Ex vivo experiments also revealed cytokine plasticity within individual clones, supporting the hypothesis that these cells adapt to persistent antigens during healthy aging, although their direct role in longevity remains unproven.
 
 
 These simple fitness tests revealed which older adults had the lowest death risk
 
These simple fitness tests revealed which older adults had the lowest death riskObjective fitness tests in 13,423 Taiwanese adults aged 65 years or older linked better balance, agility, lower-body strength, and cardiorespiratory fitness with lower all-cause mortality over a median seven years. A multidomain fitness index showed the strongest association, suggesting that simple performance tests may add useful information to conventional geriatric risk assessment.
 
 
 Higher BPA exposure tracked with higher estrogen and progesterone in women
 
Higher BPA exposure tracked with higher estrogen and progesterone in womenResearchers found that higher urinary concentrations of BPA and several phthalate metabolites were associated with higher serum estrogen and progesterone levels in 90 premenopausal women from Iran. The cross-sectional study also identified positive associations for combined chemical exposures, although the authors cautioned that the mixture findings are exploratory and cannot establish causality.
 
 
 COVID-19 mortality gap between men and women narrowed sharply as the pandemic progressed
 
COVID-19 mortality gap between men and women narrowed sharply as the pandemic progressedMen experienced higher absolute excess mortality than women across many high-income countries during the COVID-19 pandemic, particularly during pre-vaccine mortality peaks. Relative differences were much smaller, showing that sex disparities depended strongly on baseline mortality, age, country, and pandemic phase.
 
 
 A two-year diet trial challenges the idea that weight loss is the only result that matters
 
A two-year diet trial challenges the idea that weight loss is the only result that mattersIn the two-year DELISH randomized trial, adults with obesity achieved modest, sustained weight loss with either an adapted Mediterranean-style program or a commercial weight loss program. The Mediterranean-style intervention produced greater improvements in self-reported diet quality, while 24-month weight loss did not materially differ between groups.
 
 
 Moderate fruit juice intake could help close vitamin C gaps in UK diets
 
Moderate fruit juice intake could help close vitamin C gaps in UK dietsUK dietary modeling found that fruit juice contributed substantially to vitamin C intake, although around four in five participants already met the national Reference Nutrient Intake. The simulations examined whether changing fruit juice consumption among existing consumers or introducing moderate intake among non-consumers could improve vitamin C adequacy while limiting additional free sugars.
 
 
 This 29-year heart study tracked what happens after smokers quit
 
This 29-year heart study tracked what happens after smokers quitLong-term data from the Copenhagen City Heart Study linked both current and former smoking with a higher risk of sudden cardiac death, with risk rising alongside cumulative smoking exposure. Among former smokers, risk generally declined with longer time since quitting and approached that of never smokers only after prolonged abstinence.
 
 
 Australian researchers uncover a promising new way to tackle triple-negative breast cancer
 
Australian researchers uncover a promising new way to tackle triple-negative breast cancerAustralian researchers have uncovered a promising new way to tackle one of the most aggressive forms of breast cancer, raising hopes for more effective treatments to stop the disease from spreading.
 
 
 Prenatal exposure to higher water fluoride levels associated with lower child cognition
 
Prenatal exposure to higher water fluoride levels associated with lower child cognitionPregnant mothers who lived in neighborhoods where public drinking water fluoride levels were near or above the current U.S. recommended levels tended to have children who scored lower on tests of fluid reasoning as fluoride levels increased, according to a new study supported by the National Institutes of Health's Environmental influences on Child Health Outcomes (ECHO) Program.
 
 
 A single blood test could offer a glimpse of disease risk years in advance
 
A single blood test could offer a glimpse of disease risk years in advanceMachine learning-derived cellular aging clocks mapped more than 7,000 plasma proteins to over 40 cell types, revealing marked differences in how individual cell populations age. These blood-based signatures were associated with future risks of Alzheimer’s disease, ALS, lung cancer, type 2 diabetes, and mortality across follow-up extending to 15 years.
 
 
 Review uncovers how tryptophan metabolism affects female reproductive health
 
Review uncovers how tryptophan metabolism affects female reproductive healthIn recent years, issues concerning female reproductive health have become a global challenge that cannot be ignored.
 
 
 Global study reveals rising chronic kidney disease burden in women
 
Global study reveals rising chronic kidney disease burden in womenChronic kidney disease is now the seventh leading cause of death among noncommunicable diseases globally, affecting 11–13% of the adult population.
 
 
 Psychological factors determine maternal readiness to care for newborns
 
Psychological factors determine maternal readiness to care for newbornsThe first days after childbirth are a time of profound change – not only physically, but emotionally as well. Although the rooming-in model, in which mothers and newborns stay together around the clock, is standard practice in maternity wards, not every woman feels ready to care for her baby independently from the very first hours after delivery.
 
 
 Scientists identify molecule driving one of the deadliest forms of breast cancer
 
Scientists identify molecule driving one of the deadliest forms of breast cancerAustralian researchers have uncovered a promising new way to tackle one of the most aggressive forms of breast cancer, raising hopes for more effective treatments to stop the disease from spreading.
 
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