| |  An international group led by researchers from the RIKEN Center for Integrative Medical Sciences (IMS) in Japan have discovered associations between pathogenic variants of the BRCA 1 and 2 genes and four types of cancer. Published in ESMO Open, the findings expand the potential for personalized medicine to several cancer types that currently have limited treatment options and poor prognoses. | |
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| |  The US Food and Drug Administration (FDA) is reviewing a petition to revoke the approval of Roche's top-selling drug ocrelizumab (Ocrevus) for treating primary progressive multiple sclerosis (PPMS) - a form of MS thought to affect around 15 % of patients. | |
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| |  A study links maternal use of cholesterol-inhibiting medications during pregnancy to increased autism risk in children, urging caution in prescribing practices. | |
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| |  Researchers analyzing 2.46 million ambulance dispatches across 13 Chinese cities found that humidity can intensify the health risks linked to both hot and cold temperatures, with cold-dry and warm-wet conditions posing the greatest risks. Future climate projections suggest compound temperature-humidity events will become more frequent and increasingly shift health burdens toward heat-related events in China. | |
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| |  Repeated menstrual cycles may do more than trigger endometriosis. They may rewire the brain. | |
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| |  Older adults who took longer and more frequent daytime naps, especially in the morning, had a higher risk of all-cause mortality in this prospective cohort study using actigraphy-based nap tracking. Variability in nap duration from day to day was not associated with mortality after full adjustment. | |
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| |  A qualitative study of 30 UK adults found that many people see ultra-processed foods as unhealthy but struggle to define them clearly or distinguish them from other processed foods. The findings suggest that clearer communication and food-environment changes, not education alone, may be needed to help people reduce UPF intake. | |
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| |  In a large ASPREE and ASPREE-XT nested case-control study of older adults without prior cardiovascular disease, people who later experienced a CVD event showed faster cognitive decline beginning roughly 3 to 8 years before the event. Processing speed declined earliest, suggesting that subtle cognitive changes may emerge well before overt cardiovascular disease. | |
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| |  Researchers created a new questionnaire to measure major life changes linked to psychedelic use and found that most surveyed adults reporting naturalistic psychedelic use said psychedelics had influenced at least one major change in their lives. These changes most often involved goals, values, and spirituality, were usually rated positively, and were more commonly reported by people with more frequent use. | |
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| |  Urban environments shape microbial exposure through building design, occupancy, ventilation, moisture, and contact with green space, with important consequences for infection risk, immune development, and respiratory health. | |
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| |  New research links stress, BMI, and hormone patterns to pubertal timing, revealing implications for long-term health and early intervention strategies. | |
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| |  Babies who are exclusively breastfed for at least three months carry markers in their blood that differ from babies who are not breastfed. | |
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| |  The number of babies born in the United States fell again last year. | |
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| |  Most oncologists say they would prescribe hormone therapy to cervical cancer patients who experience early menopause from radiation treatment, but barriers are keeping many from doing so in practice, according to a new University of Kentucky Markey Cancer Center study published in JAMA Network Open. | |
