Using Assays for Carbonic Anhydrase Activity and Inhibitor Screening
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#ALT# Using Assays for Carbonic Anhydrase Activity and Inhibitor Screening

Carbonic anhydrase (CA) is a zinc-based metalloprotease found in at least 14 various isoforms in mammals. It catalyzes the reversible hydration of carbon dioxide (CO2) to produce proton and bicarbonate, thus playing a major role in pH and CO2 homeostasis. Alterations in CA activity are linked to various diseases such as type II diabetes mellitus, glaucoma, liver diseases, lung diseases, and so on.

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