Environmental exposures affect genes linked to respiratory diseases much more than genetic ancestry
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#ALT# Real-Time qPCR Comparing Reagent Performance

Testing previously optimized qPCR assays with a new qPCR master mix requires careful experimental design to look at several factors of reagent performance including assay specificity, repeatability, linearity, sensitivity and efficiency.

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   Environmental exposures affect genes linked to respiratory diseases much more than genetic ancestryEnvironmental exposures affect genes linked to respiratory diseases much more than genetic ancestry
 
Researchers have found strong evidence that environmental exposures, including air pollution, affect gene expressions associated with respiratory diseases much more than genetic ancestry.
 
   UNC Lineberger study identifies genetic clues that explain how breast cancer metastasizesUNC Lineberger study identifies genetic clues that explain how breast cancer metastasizes
 
Breast cancer is the second leading cause of cancer death in women in the United States, with most deaths caused by the cancer spreading beyond the breast.
 
 Researchers identify genetic variations that affect blood pressure using cigarette smoking behavior
 
Researchers identify genetic variations that affect blood pressure using cigarette smoking behaviorUsing a technique that is opening the door to more complex analyses of the human genome, researchers have identified dozens of new genetic variations that affect blood pressure.
 
 
 BC Platforms' new GeneVision uses Microsoft Genomics Service to deliver end-to-end precision medicine
 
BC Platforms' new GeneVision uses Microsoft Genomics Service to deliver end-to-end precision medicineBC Platforms, a pioneer in genomic data management and analytics, today announces it has launched GeneVision, a new end-to-end Solution for Precision Medicine, that uses the Microsoft Genomics service which runs on Microsoft Azure.
 
 
 Myriad Genetics shows strong commitment, support in the fight against colorectal cancer
 
Myriad Genetics shows strong commitment, support in the fight against colorectal cancerMyriad Genetics, Inc., a leader in molecular diagnostics and personalized medicine, continues to demonstrate an unmatched commitment to hereditary cancer risk assessment and genetic testing during National Colorectal Cancer Awareness Month.
 
 
 New technique provides pairs of genetically matched cells to study disease
 
New technique provides pairs of genetically matched cells to study diseaseResearchers led by Dr. Knut Woltjen report a new gene editing method that can modify a single DNA base in the human genome with absolute precision.
 
 
 Scientists identify single genetic change in Salmonella that plays key role in bloodstream infections
 
Scientists identify single genetic change in Salmonella that plays key role in bloodstream infectionsScientists have identified a single genetic change in Salmonella that is playing a key role in the devastating epidemic of bloodstream infections currently killing around 400,000 people each year in sub-Saharan Africa.
 
 
 Researchers develop gene therapy that treats a form of macular degeneration in canine model
 
Researchers develop gene therapy that treats a form of macular degeneration in canine modelResearchers from the University of Pennsylvania have developed a gene therapy that successfully treats a form of macular degeneration in a canine model.
 
 
 UAB scientists explore gene therapy for frontotemporal dementia
 
UAB scientists explore gene therapy for frontotemporal dementiaGene therapy has shown promise for treating a neurodegenerative disease known as frontotemporal dementia and a related condition called neuronal ceroid lipofuscinosis, according to new findings presented in the Journal of Neuroscience by researchers from the University of Alabama at Birmingham.
 
 
 New compounds targeting epigenetics show promise in lymphoma patients
 
New compounds targeting epigenetics show promise in lymphoma patientsNew compounds targeting epigenetics have shown remarkable early activity in patients with lymphoma, according to data presented at the TAT (Targeted Anticancer Therapies) International Congress 2018 in Paris, France.
 
 
 Researchers discover 50 new gene regions that increase risk of schizophrenia
 
Researchers discover 50 new gene regions that increase risk of schizophreniaResearchers at the MRC Centre for Neuropsychiatric Genetics and Genomics at Cardiff University have discovered 50 new gene regions that increase the risk of developing schizophrenia.
 
 
 Researchers develop genetic bar codes for superfoods
 
Researchers develop genetic bar codes for superfoodsChia seeds, Moringa powder, Açai or Goji berries, the list of foods with alleged health benefits is increasing constantly. Health-conscious consumers love "superfoods" that are attributed stress-reducing and detoxifying properties as well as properties strengthening the immune system.
 
 
 Quiescent cells also acquire particular type of mutation, research shows
 
Quiescent cells also acquire particular type of mutation, research showsFor almost a hundred years, geneticists have believed that the more a cell divides the more mutations it acquires. However, research by scientists at the Institut Pasteur shows that quiescent cells, which do not divide, also acquire a particular type of mutation - deletions (mutations through loss of nucleobases).
 
 
 Study findings establish basis for epigenetic link between aging and Alzheimer's disease
 
Study findings establish basis for epigenetic link between aging and Alzheimer's diseaseAlthough certain genetic variants increase the risk of Alzheimer's disease (AD), age is the strongest known risk factor. But the way in which molecular processes of aging predispose people to AD, or become impaired in AD remains a mystery.
 
 
 Scientists identify genes involved in age-related brain deterioration
 
Scientists identify genes involved in age-related brain deteriorationA group of genes and genetic switches involved in age-related brain deterioration have been identified by scientists at the Babraham Institute, Cambridge and Sapienza University, Rome.
 
 
 What is Patau Syndrome?
 
What is Patau Syndrome?Patau’s syndrome, also referred to as Trisomy 13, is a chromosome-based, rare genetic disorder in which the some or all of a patients cell contain an extra copy of chromosome 13. Normally a baby should have two copies of the chromosome, and this additional chromosome causes abnormal development of the fetus, often resulting in a miscarriage or stillbirth.
 
 
 UNIGE researchers discover why premature cell division promotes tumor formation
 
UNIGE researchers discover why premature cell division promotes tumor formationThe accumulation of mutations in the human genome is at the origin of cancers, as well as the development of resistance to treatments. The Cyclin E and Myc genes are active in the control of cell division.
 
 
 Study unlocks big puzzle in familial breast cancer
 
Study unlocks big puzzle in familial breast cancerMutations in known breast cancer genes such as BRCA1 and BRCA2 are identified in only approximately 20 per cent of women who are offered genetic testing for familial breast cancer.
 
 
 Mechanisms of DNA Repair
 
Mechanisms of DNA RepairThere are two general classes of DNA repair; the direct reversal of the chemical process generating the damage and the replacement of damaged nucleotides.
 
 
 What is Edward's Syndrome?
 
What is Edward's Syndrome?Edward’s syndrome is a genetic defect that causes several abnormalities in babies with this chromosomal condition. There is no cure for the condition, which causes death shortly after birth. It is also referred to as Trisomy 18 and affects one in five thousand live births. The chances of a woman giving birth to a child with Edward's syndrome increases with the age of the pregnant woman.