Next-generation ‘active genetics’ tool opens new horizons
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  February 7, 2018  
  Genetics  
  The latest Genetics news from News Medical  
 Next-generation ‘active genetics’ tool opens new horizonsNext-generation ‘active genetics’ tool opens new horizons
 
In 2015, University of California San Diego biologists Ethan Bier and Valentino Gantz developed a breakthrough technology known as "active genetics," which results in parents transmitting a genetic trait to most of their offspring (instead of 50 percent receiving the trait under standard inheritance).
 
   Steven R. Brant shines light on genetic causes for IBDSteven R. Brant shines light on genetic causes for IBD
 
Whether he is sailboat racing on the Chesapeake Bay or researching genetic causes for inflammatory bowel disease, Steven R. Brant values one quality above all others: a strong team.
 
   Study shows connection between genetic variants for ADHD and educational attainmentStudy shows connection between genetic variants for ADHD and educational attainment
 
A study published in the February 2018 issue of the Journal of the American Academy of Child and Adolescent Psychiatry reports that five novel genetic variants associated with attention-deficit/hyperactivity disorder (ADHD) have been identified by exploiting genetic overlap between ADHD and educational attainment.
 
 Researchers develop gene therapy for idiopathic pulmonary fibrosis
 
Researchers develop gene therapy for idiopathic pulmonary fibrosisResearchers have successfully identified the genetic cause of idiopathic pulmonary fibrosis and have shown success in trials of a new gene therapy.
 
 
 Scientists develop new system to match genetic anomalies with precision medicine treatments
 
Scientists develop new system to match genetic anomalies with precision medicine treatmentsA team of computer scientists from the University of Delaware and Georgetown University has developed a new system to rapidly determine which cancer drugs are likely to work best given a patient's genetic markers.
 
 
 Novel method can edit genes with substantially fewer errors
 
Novel method can edit genes with substantially fewer errorsGene therapy is an emerging strategy to treat diseases caused by genetic abnormalities. One form of gene therapy involves the direct repair of a defective gene, using genome-editing technology such as CRISPR-Cas9. Despite its therapeutic potential, genome editing can also introduce unwanted and potentially harmful genetic errors that limit its clinical feasibility.
 
 
 Higher susceptibility of some babies to Zika virus has a genetic origin, study shows
 
Higher susceptibility of some babies to Zika virus has a genetic origin, study showsMicrocephaly, brain calcification, skeletal alterations, auditory and visual deficits - these are examples of the damage that can be caused by Zika virus in babies born to mothers infected during pregnancy.
 
 
 Scientists discover the genetic cause of immune disorders
 
Scientists discover the genetic cause of immune disordersScientists from the Cincinnati Children’s have successfully identified a gene mutation that affects T cell function and promotes immune disorders.
 
 
 Researchers identify cause of severe genetic disease
 
Researchers identify cause of severe genetic diseaseMutations in the p63 protein lead to a number of disorders, but none is as severe as the AEC syndrome. Scientists at Goethe University Frankfurt in collaboration with a research group from the University of Naples Federico II have now discovered that this syndrome resembles diseases such as Alzheimer's, Parkinson's or ALS more closely than it does other p63-based syndromes.
 
 
 Stealth gene shuttles open up new avenues to treat aggressive cancers
 
Stealth gene shuttles open up new avenues to treat aggressive cancersViruses have their own genetic material and can infect human cells in a very specific manner. They will then reproduce as directed by their own genes but using the resources of the host cell.
 
 
 Scientists discover rare hypertension disease gene
 
Scientists discover rare hypertension disease geneMore than a billion people worldwide suffer from high blood pressure (hypertension). Prolonged hypertension damages blood vessels, which can result in damage to the heart, the kidneys, and the brain. Possible consequences include heart attack, kidney failure, and stroke.
 
 
 Study reveals the mechanism of common DNA mutations
 
Study reveals the mechanism of common DNA mutationsResearchers at The Ohio University have uncovered the mechanism by which thymine and guanine, the most commonly mutated bases in DNA, become damaged.