Rising bowel and ovarian cancer rates in younger adults raise new concerns
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 Implantable cytokine factories show promise against advanced ovarian cancerImplantable cytokine factories show promise against advanced ovarian cancer
 
Implantable cytokine factories designed to deliver immunotherapy directly at the site of disease have taken an important step toward clinical reality.
 
 
 Rising bowel and ovarian cancer rates in younger adults raise new concernsRising bowel and ovarian cancer rates in younger adults raise new concerns
 
Cases of several cancers are rising in England among both younger and older adults, but rates of bowel and ovarian cancer are rising only among younger adults (under 50s), finds research published in the open access journal BMJ Oncology.
 
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This review explains how glucose scarcity, lipid disruption, amino acid deprivation, and toxic metabolites weaken CAR-T cells inside solid tumors. It highlights metabolic reprogramming as a promising strategy to improve CAR-T cell persistence, adaptability, and anti-tumor function.
 
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Engineered nanoparticles can improve cancer immunotherapy by delivering drugs, antigens, and genetic payloads with greater precision while remodeling the tumor microenvironment. The review highlights how nano-immunotherapy could boost immune activation, improve checkpoint-blockade responses, and support more personalized cancer treatment, although safety, scalability, and clinical translation challenges remain.
 
   The importance of genetic screening for all cancer survivorsThe importance of genetic screening for all cancer survivors
 
Hundreds of thousands of people diagnosed with cancer are still alive today but were never genetically tested, either because testing was not available or was not routinely offered at the time of their diagnosis. These patients are just as likely as those diagnosed today to carry a germline pathogenic variant (gPV) - a heritable genetic alteration - that increases cancer risk.
 
 Common cholesterol drug may help disrupt ovarian cancer cell protection
 
A fluid that women with advanced ovarian cancer know all too well - ascites, the buildup of liquid in the belly - may be doing more than causing discomfort.
 
 
 How to use biomarkers to accelerate clinical development success
 
How to use biomarkers to accelerate clinical development successLearn how to use biomarkers to accelerate clinical development success.
 
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