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The latest Alzheimer's disease news from News Medical |
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 | | |  SuperAgers retain exceptional memory through mechanisms beyond genetics Many people assume that some memory decline is an inevitable consequence of getting older. But a select group of older adults, known as SuperAgers, reach their 80s and 90s while retaining memory performance as good as or better than people in their 50s and 60s. | | | | |  Frequent TV watching links to higher white matter lesion volume ARIC researchers linked self-reported TV watching and occupational sitting in midlife with brain MRI measures obtained roughly 24 years later in 1,712 adults without dementia. Frequent TV watching was associated with greater white matter hyperintensity volume and lower volumes in several brain regions, while sitting at work was associated with lower white matter hyperintensity volume and larger selected cortical volumes. | |
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|  | | | | |  Low-dose lithium may protect brain networks in early Alzheimer’s disease This perspective examines whether restoring physiological lithium levels could help protect cognition in early Alzheimer’s disease. It proposes that lithium may support cholinergic signaling and brain connectivity, but emphasizes that rigorous, safety-monitored clinical trials are needed. | |  | | | | |  Longer activity bouts link to lower future dementia and mental health risks A UK Biobank analysis of 66,483 adults found that longer daily moderate-to-vigorous activity bouts and less fragmented activity were associated with lower subsequent risks of inpatient diagnoses of dementia, depression, and anxiety, independent of total activity time. | | | | | | |  Dementia addiction and psychiatric disorders show distinct patterns of accelerated brain aging People with dementia, mild cognitive impairment, alcohol addiction, or psychiatric disorders such as schizophrenia show increased brain aging, each in specific patterns within the brain, according to a study published July 21st in the open access journal PLOS Medicine by Shile Qi from the Nanjing University of Aeronautics and Astronautics, China, and colleagues. | |
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| | | |  Most everyday moments are quickly forgotten, while others stay with us for a lifetime. How the brain determines which memories are retained and which are lost remains an open question. | | | | |  Brain-computer interfaces (BCIs) have made remarkable progress restoring movement and speech in people with paralysis. | | | | |  Researchers have discovered that the human brain undergoes widespread age-related changes in genome regulation beginning in midlife that may help explain why aging is the greatest risk factor for neurodegenerative diseases such as Alzheimer's. | | | | |  Persistent financial hardship accelerates age-related cognitive decline, according to a new study led by University College London (UCL) researchers. | | | | |  Karyn Frick likes to think big. In college, she spent the summer after her junior year studying the neurobiology of memory in a lab at Johns Hopkins University. For hours at a time, Frick would watch rats scurry through mazes, entranced by their behavior. | | | | |  Results from a small clinical trial suggest it may be possible to reduce your risk of dementia by eating during fewer hours of the day. | | | | |  Researchers from Universidad Carlos III de Madrid (UC3M) and Hospital Universitario Severo Ochoa in Leganés, part of the public health network of the Comunidad de Madrid, have developed a methodology that uses artificial intelligence (AI) to analyze brain electrical activity during sleep and facilitate the early diagnosis of Alzheimer's. | | | | |  Our population is aging. The United Nations reports that by 2050, the number of people over the age of 85 on our planet is set to triple. | | | | |  This review finds that spermidine supports autophagy, mitochondrial function, and healthspan in experimental models, while observational studies link higher dietary intake to lower mortality. However, human trials have produced limited and mixed results, leaving its clinical role in healthy aging unresolved. | | | | |  Researchers at the University of Vermont Robert Larner, M.D. College of Medicine and Upstate Medical University in Syracuse, NY, have discovered that dengue virus can infect and replicate inside memory B cells, immune cells traditionally understood to help protect the body from infection. | | | | |  Immune dysregulation may contribute to depression, schizophrenia, bipolar disorder, and anxiety through chronic inflammation, altered neuroimmune signaling, genetic susceptibility, and stress-related epigenetic changes. Evidence also suggests that biologically defined patient subgroups may benefit from more precise, immune-informed approaches to diagnosis and treatment. | |
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