Research finds persistent prescribing of risky medications to older adults with dementia
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 Incretin-based diabetes drugs show potential protective effects against dementiaIncretin-based diabetes drugs show potential protective effects against dementia
 
A large McGill University study has found that two classes of medications commonly prescribed for Type 2 diabetes, both incretin-based, are associated with a reduced risk of dementia.
 
 
 Research finds persistent prescribing of risky medications to older adults with dementiaResearch finds persistent prescribing of risky medications to older adults with dementia
 
Despite years of clinical guidelines warning against the practice, one in four Medicare beneficiaries with dementia is prescribed brain-altering medications linked to falls, confusion, and hospitalization, according to new research to be published January 12 in the peer-reviewed journal JAMA.
 
   New European initiative aims to transform real world Alzheimer’s disease careNew European initiative aims to transform real world Alzheimer’s disease care
 
Today, the ACCESS-AD consortium is announcing the launch of a transformative European initiative that will accelerate the implementation of scientific innovations for Alzheimer's disease (AD) management in real-world health systems.
 
   Post-meal blood sugar spikes linked to increased Alzheimer's riskPost-meal blood sugar spikes linked to increased Alzheimer's risk
 
A new study led by researchers from the University of Liverpool has found that spikes in blood sugar after meals may increase the risk of Alzheimer's disease.
 
   Single-cell analysis reveals gene disruptions in early-onset Alzheimer's brain regionsSingle-cell analysis reveals gene disruptions in early-onset Alzheimer's brain regions
 
A new study led by researchers at UTHealth Houston investigated both gene expression and regulation at single cell levels to reveal disruptions in gene function in three brain regions of patients with sporadic early onset Alzheimer's disease.
 
 Elevated tau in Long COVID patients raises risk for neurodegenerative diseases
 
Elevated tau in Long COVID patients raises risk for neurodegenerative diseasesA study of 227 individuals who experienced neuro cognitive difficulties post COVID-19 infection – such as headaches, vertigo, balance dysregulation, changes in taste/smell, and brain fog – displayed a significant increase in their blood plasma of a crucial protein called tau, which is found in nerves and especially in the brain.
 
 
 Study sheds new light on how structural brain changes are tied to memory decline in aging
 
Study sheds new light on how structural brain changes are tied to memory decline in agingA landmark international study that pooled brain scans and memory tests from thousands of adults has shed new light on how structural brain changes are tied to memory decline as people age.
 
 
 MIT researchers map dynamic fuzzy coat surrounding tau protein fibrils
 
MIT researchers map dynamic fuzzy coat surrounding tau protein fibrilsOne of the hallmarks of Alzheimer's disease is the clumping of proteins called Tau, which form tangled fibrils in the brain. The more severe the clumping, the more advanced the disease is.
 
 
 Global Alzheimer’s Platform Foundation announces strategic collaboration and partnership with Spear Bio for the transformative Bio-Hermes-002 study
 
Global Alzheimer’s Platform Foundation announces strategic collaboration and partnership with Spear Bio for the transformative Bio-Hermes-002 studyThe Global Alzheimer’s Platform Foundation® (GAP) is pleased to welcome Spear Bio, a biotechnology company pioneering wash-free ultrasensitive immunoassay technology, to the Bio-Hermes-002 study.
 
 
 Study finds growing long-term antipsychotic prescribing in elderly dementia patients
 
Study finds growing long-term antipsychotic prescribing in elderly dementia patientsWhen agitated dementia patients wander or shout through the night, families and caregivers understandably feel the need to treat this frightening and potentially dangerous behavior. Antipsychotic medications are often resorted to with such patients, contributing to increases in antipsychotic treatment rates among older people.
 
 
 Detecting Alzheimer’s early: Machine learning’s role in neurological imaging
 
Detecting Alzheimer’s early: Machine learning’s role in neurological imagingSee how machine learning is spotting Alzheimer’s years before symptoms begin—using brain scans to help guide earlier, more informed care.
 
 
 Repurposed Alzheimer’s medication offers low-cost hope for sickle cell anemia
 
Repurposed Alzheimer’s medication offers low-cost hope for sickle cell anemiaSickle cell anemia is the world's most common genetic disorder. It causes the red blood pigment hemoglobin to crystallize, which results in rigid, malformed red blood cells with a sickle shape.
 
 
 Experts issue strong call for overhaul of UK dementia prevention strategy
 
Experts issue strong call for overhaul of UK dementia prevention strategyA national panel of experts has issued the strongest call yet for the Department of Health and Social Care to overhaul how it approaches dementia prevention, pointing to vital evidence that dementia risk can be reduced and providing a framework for the development of new government policy that could improve brain health for millions.
 
 
 Super agers' resilience against Alzheimer's disease linked to protective gene variant
 
Super agers' resilience against Alzheimer's disease linked to protective gene variantThe gene variant posing the greatest genetic risk of late-onset Alzheimer's disease (AD) is called APOE-ε4. A different variant of the same gene, APOE-ε2, is thought to confer protection against AD.
 
 
 A week of 40-Hz sound triggers long-lasting amyloid changes in monkeys
 
A week of 40-Hz sound triggers long-lasting amyloid changes in monkeysForty-hertz auditory stimulation in aged monkeys doubles CSF amyloid-β levels, offering insights into non-invasive strategies for Alzheimer's disease treatment.
 
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