Parasites trigger a gut-to-brain signal that cuts food intake during infection
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 Dandelion leaves boost brain-protective compounds after digestionDandelion leaves boost brain-protective compounds after digestion
 
Dandelion leaves are rich in polyphenols with neuroprotective effects, offering insights into natural strategies for Alzheimer's disease management.
 
 
 Parasites trigger a gut-to-brain signal that cuts food intake during infectionParasites trigger a gut-to-brain signal that cuts food intake during infection
 
Researchers found that intestinal tuft cells signal to crypt enterochromaffin cells by releasing acetylcholine, triggering serotonin release and activating a gut-to-brain vagal pathway during type 2 inflammation. This sustained signalling, rather than the initial acute response, was linked to reduced food intake in mouse models of parasitic infection.
 
   Chronic colitis reshapes colon stem cells in ways that can accelerate tumour growthChronic colitis reshapes colon stem cells in ways that can accelerate tumour growth
 
Researchers showed that chronic colitis leaves a long-lasting epigenetic memory in colonic stem cells, persisting for more than 100 days after recovery in mice. This memory is marked by durable AP-1-linked chromatin changes and later amplifies tumour outgrowth after oncogenic mutation.
 
   Hospital delirium associated with increased likelihood of future dementiaHospital delirium associated with increased likelihood of future dementia
 
Older adults who develop delirium during a hospital admission face a substantially higher risk of dementia in later years, even if they had no prior health conditions, according to a major new population study.
 
   Massive clinical trial investigates brain training to delay dementia onsetMassive clinical trial investigates brain training to delay dementia onset
 
An expansive clinical trial led by USF researchers and aimed at delaying the onset of dementia continues to receive major federal support for addressing a public health crisis.
 
 Gut immune responses found to trigger brain inflammation in MS
 
Gut immune responses found to trigger brain inflammation in MSMultiple sclerosis (MS) is a debilitating neurological disorder caused by malfunctioning immune responses that target the brain and spinal cord of the central nervous system (CNS).
 
 
 Chronic inflammation leaves epigenetic scars that increase future cancer risk
 
Chronic inflammation leaves epigenetic scars that increase future cancer riskChronic inflammation can raise a person's risk of cancer, and a new study reveals key details about how that might happen in the gut and points to better ways to identify and reduce risk.
 
 
 Taking a placebo knowingly still improves stress and memory
 
Taking a placebo knowingly still improves stress and memoryResearch indicates open-label placebos can ease stress and boost memory in older adults, presenting a novel, ethical strategy for promoting healthy aging.
 
 
 Cerebrospinal fluid marker enhances accuracy in diagnosis of Parkinson’s and Lewy body dementia
 
Cerebrospinal fluid marker enhances accuracy in diagnosis of Parkinson’s and Lewy body dementiaAn international consortium has achieved a major breakthrough in the diagnosis of neurological diseases. In a recent publication in the scientific journal Nature Medicine, they describe the discovery of a new quantitative biomarker in lumbar fluid (cerebrospinal fluid) that is helping doctors to diagnose Parkinson's disease and Lewy body dementia more accurately.
 
 
 New brain atlas reveals how the human neocortex forms over time
 
New brain atlas reveals how the human neocortex forms over timeIn a bid to better understand, and potentially treat, a host of conditions that affect early cognition, neurodevelopment and the brain later in life, investigators at Johns Hopkins Medicine and colleagues throughout the world have been mapping the molecular construction of the human brain.
 
 
 Can AI chatbots help brain tumor patients understand their care?
 
Can AI chatbots help brain tumor patients understand their care?Integrating LLMs in brain tumor care could enhance patient understanding, but requires strict oversight to manage risks and ensure reliable information.
 
 
 Spear Bio introduces new ultra-sensitive neurodegenerative assays and expands direct access at AD/PD 2026
 
Spear Bio introduces new ultra-sensitive neurodegenerative assays and expands direct access at AD/PD 2026Spear Bio, an innovator in ultrasensitive protein biomarker detection, showcased three new SPEAR UltraDetect™ immunoassays—brain-derived p-Tau 217 (BD-pTau 217), α-synuclein (α-syn) and phospho-Ser129-α-synuclein (pS129-α-syn)—at the International Conference on Alzheimer’s & Parkinson’s Diseases (AD/PD 2026) last week.
 
 
 Research explains why stomach bugs cause a lingering loss of appetite
 
Anyone who has weathered a bad stomach bug knows the feeling: a loss of appetite that sets in and lingers, even after the initial illness.
 
 
 Short bursts of vigorous activity can lower risk of major diseases
 
People who get just a few minutes of vigorous activity daily are less likely to develop eight major diseases, including arthritis, heart disease and dementia, according to research published in the European Heart Journal today (Monday).
 
 
 Mentally active sitting linked to reduced risk of dementia
 
New research distinguishing between passive and mentally active sitting in association with dementia has found that adults who engaged in extended durations of mentally passive sedentary behaviors had a higher risk of dementia.
 
 
 Severe infections linked to higher dementia risk independent of coexisting illnesses
 
Severe infections increase the risk of dementia independently of other coexisting illnesses, according to a new study published March 24th in the open-access journal PLOS Medicine by Pyry Sipilä of the University of Helsinki, Finland, and colleagues.
 
 
 Walking patterns help distinguish Lewy body dementia from Parkinson’s
 
Doctors often struggle to distinguish early dementia with Lewy bodies from early Parkinson's disease.
 
 
 Extreme cold linked to sharp rise in heart-related deaths
 
On the heels of one of the coldest winters in memory for large swaths of the country, new research highlights an often overlooked cost of cold weather: months with lower temperatures see significantly greater rates of death from heart attacks, strokes and coronary artery disease than milder months.
 
 
 Passion fruit molecule may help prevent Alzheimer’s disease progression
 
Four years ago, a research group at the University of Oslo made what would turn out to be a major discovery.
 
 
 Home cooking may help prevent dementia in seniors
 
Preparing a home cooked meal at least once a week may cut older people's risk of dementia by 30%, suggests research published online in the Journal of Epidemiology & Community Health.
 
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