High-dose flu shots inked to lower Alzheimer's dementia risk in older adults
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 Gut microbiome changes improve memory in early cognitive declineGut microbiome changes improve memory in early cognitive decline
 
Research shows that modifying the gut microbiome can enhance cognitive performance and mitigate dementia risk, highlighting the gut-brain connection.
 
 
 High-dose flu shots inked to lower Alzheimer's dementia risk in older adultsHigh-dose flu shots inked to lower Alzheimer's dementia risk in older adults
 
A large US claims-based study found that adults aged 65 and older who received a high-dose flu vaccine had a lower observed risk of Alzheimer dementia than those who received a standard-dose vaccine, with the association lasting up to 25 months in per-protocol analyses and 28 months in intention-to-treat analyses.
 
   Could vitamin D in midlife protect your brain from early Alzheimer’s?Could vitamin D in midlife protect your brain from early Alzheimer’s?
 
Higher serum vitamin D in midlife is associated with reduced tau burden in the brain, highlighting its potential role in early dementia risk assessment.
 
   NIH funds AI project to advance Alzheimer’s research and treatmentNIH funds AI project to advance Alzheimer’s research and treatment
 
The National Institutes of Health has renewed support for Artificial Intelligence for Alzheimer's Disease, or AI4AD. The new $12.6 million award to advance the project's next phase, AI4AD2, brings its total investment in AI4AD to $30.7 million.
 
   Blood test may detect cognitive decline years before symptomsBlood test may detect cognitive decline years before symptoms
 
A blood test could help identify people at higher risk of cognitive decline years before a traditional diagnosis is possible – according to University of East Anglia research.
 
 Study reveals pearling mechanism behind mitochondrial DNA spacing
 
Mitochondria are often described as the cell's power plants, because they generate energy. To help them achieve this, mitochondria carry their own small genome called mitochondrial DNA (mtDNA).
 
 
 Vitamin D levels in midlife tied to lower dementia risk marker
 
Having higher levels of vitamin D in the blood in middle age is associated with lower levels of tau protein in the brain, which is a sign of dementia, years later, according to a study published April 1, 2026, in Neurology Open Access, an official journal of the American Academy of Neurology.
 
 
 Researchers uncover a chain of molecular events behind early brain changes in Alzheimer's
 
For the millions of people who carry the gene APOE4, the strongest known genetic risk factor for Alzheimer's disease, their brain activity may begin changing long before any memory problems appear.
 
 
 Study shows how environmental factors accelerate biological age of the brain
 
The latest findings from the Global Brain Health Institute (GBHI) at Trinity College Dublin identify important brain health implications for prevention, public health, and policy.
 
 
 High-dose flu vaccine linked to lower Alzheimer’s disease risk
 
A UTHealth Houston physician's visit to a local public health building sparked community awareness and inspired a new research idea.
 
 
 Lack of dental care linked to higher heart and dementia risk
 
Lack of dental care linked to higher heart and dementia riskBeing unable to afford dental care may increase a person's risk of developing cardiovascular disease or dementia, according to a new study led by researchers at Boston University School of Public Health (BUSPH).
 
 
 The brain encodes time and space through common neural sequences
 
The brain encodes time and space through common neural sequencesIf you develop Alzheimer's disease, you not only lose your sense of time, but you also lose your sense of place. Could time and place be two sides of the same coin?
 
 
 Smoking shrinks key brain regions while cannabis shows weaker effects
 
Smoking shrinks key brain regions while cannabis shows weaker effectsThe study highlights brain changes from tobacco use and calls for more research on cannabis, as its effects on brain structure remain inadequately understood.
 
 
 Salt-adding behavior varies by gender and lifestyle factors
 
Salt-adding behavior varies by gender and lifestyle factorsSalt has been used as seasoning and food preservative for thousands of years, but having too much of it can lead to various diseases, including high blood pressure, cardiovascular diseases, and kidney disease.
 
 
 New blood biomarker improves cancer risk detection in people with Lynch Syndrome
 
New blood biomarker improves cancer risk detection in people with Lynch SyndromeResearchers at The University of Texas MD Anderson Cancer Center have discovered a new blood-based biomarker that can help identify and characterize asymptomatic people with Lynch Syndrome (LS) who are more susceptible to developing cancer based on early immune detection signatures, allowing clinicians to stratify patients based on their personal risk level.
 
 
 Small molecule may block protein buildup in neurodegenerative diseases
 
A team of researchers from NYU Abu Dhabi and the University of Denver have identified a promising small molecule that could help slow or halt the progression of serious brain diseases such as Parkinson's disease, offering new hope for treatments that go beyond managing symptoms.
 
 
 Oral molecule prevents kidney stones and restores survival in mice
 
Scientists at the Buck Institute for Research on Aging have shown that an orally administered small molecule, N-propargylglycine (N-PPG), can completely prevent the formation of calcium oxalate kidney stones, protect against kidney failure, and fully restore normal survival in a mouse model of Primary Hyperoxaluria Type 2 (PH2), a rare and currently untreatable genetic disorder that causes progressive kidney failure in infants and young adults.
 
 
 Music boosts vivid mental imagery while traffic noise changes where the mind goes
 
Music boosts vivid mental imagery while traffic noise changes where the mind goesMusic and traffic noise both changed how people imagined a simple journey, but they did so differently: music boosted vividness, positive tone, imagined time, and distance, while traffic noise mainly increased vividness, distance, and traffic-related imagery content. The study suggests that everyday soundscapes can shape mental imagery in complex ways, with possible implications for imagery-based therapies and other real-world settings.
 
 
 First participants join clinical study to fast-track dementia research in the UK
 
First participants join clinical study to fast-track dementia research in the UKThe Dementia Trials Accelerator has taken a significant step towards transforming dementia clinical trials in the UK by welcoming its first participants into clinics for simple tests that will ultimately get the right people into clinical trials quicker, speeding up vital research.
 
 
 New research challenges traditional models of language processing
 
New research challenges traditional models of language processingMultiple regions of the brain engage in fast-moving conversations to understand language, UTHealth Houston researchers have discovered, dispelling a prior school of thought that only one region of the brain was responsible for language processing.
 
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