Brain cells amplify important signals to guide focus and navigation
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 Can aging bring improvement instead of decline? Long-term study says yesCan aging bring improvement instead of decline? Long-term study says yes
 
A large longitudinal study of U.S. adults found that many older people improve in cognitive function or walking speed over time, challenging the idea that aging inevitably leads to decline. Positive beliefs about aging were associated with higher odds of improvement in both cognitive and physical health.
 
 
 Brain cells amplify important signals to guide focus and navigationBrain cells amplify important signals to guide focus and navigation
 
Nerve cells in the brain are constantly bombarded with information from different senses simultaneously. How can the brain prioritize what is most important?
 
   New study shows the brain reactivates memories without reaching conscious thoughtNew study shows the brain reactivates memories without reaching conscious thought
 
Researchers have used brain imaging to show how memories can be reactivated in the brain without them reaching conscious awareness, showing that these memories persist even when we think they have been forgotten.
 
   Researchers propose that Parkinson’s disease may start in the gut, not the brainResearchers propose that Parkinson’s disease may start in the gut, not the brain
 
A perspective in The Journal of Clinical Investigation argues that environmental exposures may interact with the gut microbiome and intestinal barrier to trigger biological processes linked to Parkinson’s disease. The authors propose that cumulative environmental stressors can erode host resilience, promoting α-synuclein pathology, immune activation, and neurodegeneration.
 
 COVID-19 lockdown timing tied to changes in executive function
 
COVID-19 lockdown timing tied to changes in executive functionThe COVID-19 pandemic affected executive function in young children, with preschoolers showing different cognitive growth patterns linked to maternal education.
 
 
 Unmasking the hyperactive circuitry of early Alzheimer’s
 
Unmasking the hyperactive circuitry of early Alzheimer’sNeuroscientists at King's College London have pinpointed a mechanism behind the increased neural connectivity observed in the very early stages of Alzheimer's disease.
 
 
 Researchers identify immune markers linked to cognitive decline after viral infections
 
Researchers identify immune markers linked to cognitive decline after viral infectionsWhat impact does a viral infection have on our memory, attention, and concentration? The COVID-19 pandemic has reignited interest in this question, which has now been extended to other infections such as HIV, herpes, and hepatitis.
 
 
 Study reveals a disease-relevant role for tanycytes in neurodegeneration
 
Study reveals a disease-relevant role for tanycytes in neurodegenerationAccumulation of the protein tau in the brain is one of the hallmarks of Alzheimer's disease. In a paper publishing March 5 in the Cell Press journal Cell Press Blue, researchers report a previously unknown mechanism that appears to enable the build-up of tau.
 
 
 Neural circuit mechanisms explain how chronic sleep loss disrupts social memory
 
Neural circuit mechanisms explain how chronic sleep loss disrupts social memorySocial memory—the ability to recognize familiar individuals and distinguish them from strangers—is fundamental to social cognition.
 
 
 Blood protein structure changes may reveal early signs of Alzheimer’s
 
Blood protein structure changes may reveal early signs of Alzheimer’sAlzheimer's disease affects an estimated 7.2 million Americans age 65 and older, according to the Alzheimer's Association.
 
 
 Hormonal imbalance and gut microbes linked to cognitive deficits in patients with PitNETs
 
Pituitary neuroendocrine tumors (PitNETs) are commonly associated with visual disturbances and endocrine abnormalities; however, many patients also experience cognitive deficits, particularly in memory, attention, and executive function, which significantly affect quality of life.
 
 
 Seniors defy stereotypes of decline through positive mindsets
 
Aging in later life is often portrayed as a steady slide toward physical and cognitive decline. But a new study by scientists at Yale University suggests an alternate narrative - that older individuals can and do improve over time and their mindset toward aging plays a major part in their success.
 
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