Breakthrough nanoparticle delivery method targets brain inflammation for multiple conditions

	Arthritis
	The latest arthritis news from News Medical

	Breakthrough nanoparticle delivery method targets brain inflammation for multiple conditions Oregon State University researchers have discovered a way to get anti-inflammatory medicine across the blood-brain barrier, opening the door to potential new therapies for a range of conditions, including Alzheimer's disease, multiple sclerosis, Parkinson's disease and cancer cachexia.

	Largest study of osteoarthritis genetics uncovers new drug targets Osteoarthritis is the leading cause of disability and chronic pain worldwide, affecting an estimated 595 million people globally.

			New genetic study reveals hundreds of clues to osteoarthritis About one in five American adults have osteoarthritis, the most common form of arthritis, according to the Centers for Disease Control and Prevention.

			Calibr-Skaggs receives FDA approval to test sCAR-T therapy in patients with autoimmune diseases Calibr-Skaggs Institute for Innovative Medicines, the drug discovery division of Scripps Research, announced today that the FDA has cleared their investigational new drug (IND) application to study switchable chimeric antigen receptor T cell (sCAR-T) therapy (CLBR001 + SWI019) in patients with autoimmune conditions.

			Why Pharmacovigilance Is More Critical Than Ever Pharmacovigilance evolves with technology, employing active surveillance to detect drug-related issues and ensure safety in an increasingly complex landscape.

	RFK Jr. struggles to navigate frustrated supporters and a demanding boss After the Senate voted to confirm Robert F. Kennedy Jr. as Health and Human Services secretary, supporters of his "Make America Healthy Again" movement cheered at having a champion in the federal government.

	What the salivary microbiome reveals about cardiovascular and neurological diseases Explore how the salivary microbiome links to heart health, Alzheimer's, and other systemic diseases.

	Refining the diagnosis of large granular lymphocytic leukemias and their mimics Large granular lymphocytic leukemias (LGLLs) are a heterogeneous group of rare chronic lymphoproliferative disorders characterized by the clonal proliferation of cytotoxic lymphocytes. Among them, T-cell LGLL (T-LGLL) and NK-cell LGLL (NK-LGLL) are the most prominent.

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