Extracellular vesicles from menstrual blood cells show potential to stimulate cartilage repair

	Arthritis
	The latest arthritis news from News Medical

	Extracellular vesicles from menstrual blood cells show potential to stimulate cartilage repair New research by an interdisciplinary team in Lithuania has revealed a promising and unconventional approach to cartilage regeneration.

	Sleep apnea raises risk of cardiovascular events and death New research to be presented at this year's European Congress on Obesity (ECO 2026, Istanbul, Turkey, 12-15 May) shows that those living with obstructive sleep apnea (OSA) have a 71% higher risk of cardiovascular events (CVEs) or death from any cause (all-cause mortality) compared with those not living with OSA.

			New compounds reduce inflammation without weakening immune defense Scripps Research scientists have developed a new class of drug compounds that reduce harmful inflammation while leaving the body's ability to fight infections intact-a long-sought goal in treating autoimmune diseases.

			FDA clears investigational new drug application to test sCAR-T therapy for autoimmune conditions Calibr-Skaggs Institute for Innovative Medicines, the drug discovery division of Scripps Research, announced today that the FDA has cleared their investigational new drug (IND) application to study switchable chimeric antigen receptor T cell (sCAR-T) therapy (CLBR001 + SWI019) in patients with autoimmune conditions.

			Duloxetine fails to prevent nerve damage caused by chemotherapy A randomized trial conducted by the Alliance for Clinical Trials in Oncology with support from the National Cancer Institute has found that duloxetine, a medication commonly used to treat chronic pain and psychiatric conditions, does not prevent nerve damage caused by chemotherapy in patients with colorectal cancer.

	Restoring tissue stiffness may reduce inflammation in gum disease Periodontitis is a serious chronic inflammatory form of gum disease that affects millions worldwide. It can lead to tooth loss and the destruction of supporting bone.

	Review identifies TREM-1 as key amplifier of inflammatory diseases Published in Current Molecular Pharmacology, a comprehensive review by Eman R. Al Sawy and colleagues from Cairo University consolidates evidence on the triggering receptor expressed on myeloid cells-1 (TREM-1) as a central amplifier of inflammatory responses.

	Novel ENDOtollins block harmful inflammation while preserving infection response Scripps Research scientists have developed a new class of drug compounds that reduce harmful inflammation while leaving the body's ability to fight infections intact-a long-sought goal in treating autoimmune diseases.

	Artemin identified as marker and target in feline osteoarthritis By comparing osteoarthritis pain pathways known to be active in dogs and humans to those in cats with degenerative joint disease (DJD), researchers found that elevation of a particular molecule, artemin, could serve as a marker of disease (and possibly pain) as well as a potential therapeutic target.

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