Low-calorie diets linked to higher psoriatic arthritis risk, genetic study suggests
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 Obesity’s health risks shift with age and sex, new genetic study revealsObesity’s health risks shift with age and sex, new genetic study reveals
 
Using a new time-resolved Mendelian randomization approach in over 360,000 UK Biobank participants, Karlsson et al. revealed that the causal impact of obesity changes across life, with distinct age- and sex-specific risk patterns for diabetes, heart disease, atrial fibrillation, and osteoarthritis.
 
 
 Low-calorie diets linked to higher psoriatic arthritis risk, genetic study suggestsLow-calorie diets linked to higher psoriatic arthritis risk, genetic study suggests
 
This Mendelian randomization study found that low-calorie diets may slightly increase the risk of psoriatic arthritis, while vegetarian and gluten-free diets showed no causal links to psoriasis, acne, or atopic dermatitis. The findings challenge assumptions about universally beneficial dietary patterns and highlight the need for cautious interpretation of dietary interventions in inflammatory skin disease.
 
   Why pomegranate is good for you: Evidence-based insights into its health benefitsWhy pomegranate is good for you: Evidence-based insights into its health benefits
 
Discover how one ancient fruit’s modern science reveals its power to fight inflammation, protect the heart, and support overall vitality through natural bioactive compounds.
 
   People with multiple sclerosis found to have dysbiotic oral microbiomePeople with multiple sclerosis found to have dysbiotic oral microbiome
 
With ads everywhere for pro- or pre-biotic foods and supplements, most people are familiar with the gut microbiome-the trillions of bacteria, fungi, and viruses that colonize our digestive tract-and the idea that keeping our gut microbiome healthy improves our overall health.
 
   Football injuries, not injections, explain why retired players face higher osteoarthritis riskFootball injuries, not injections, explain why retired players face higher osteoarthritis risk
 
Retired UK male footballers face a markedly higher risk of foot and ankle osteoarthritis (OA), primarily due to prior injuries sustained during their careers. While corticosteroid injections were linked with OA, this association likely reflects treatment for injury rather than a direct cause.
 
 Rozanolixizumab prevents congenital heart block in high-risk pregnancy
 
Rozanolixizumab prevents congenital heart block in high-risk pregnancyCongenital heart block, sometimes referred to as cardiac neonatal lupus, is a rare but potentially life-threatening condition that affects babies born to mothers with specific autoantibodies - called anti-SSA/Ro antibodies - which can attack the fetal heart via its electrical conduction system, leading to a slower heart rate.
 
 
 Smart implants and closed-loop systems: The next generation of therapeutic devices
 
Smart implants and closed-loop systems: The next generation of therapeutic devicesSmart implants and closed-loop systems are at the forefront of precision healthcare, enabling real-time diagnostics and personalized therapeutic interventions.
 
 
 New genetic marker may improve the ability to predict life-threatening reactions to gout medication
 
New genetic marker may improve the ability to predict life-threatening reactions to gout medicationA newly identified genetic marker may significantly improve the ability to predict life-threatening reactions to the gout medication allopurinol in U.S. patients.
 
 
 Discovery of glucocorticoid receptor multimerization opens path to safer therapies
 
Discovery of glucocorticoid receptor multimerization opens path to safer therapiesDrugs to treat inflammatory and autoimmune diseases - such as asthma, psoriasis, rheumatoid arthritis or Chrousos syndrome - act mainly through the glucocorticoid receptor (GR).
 
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