First-of-its-kind pregnancy hormone test reveals why female IBD patients face severe symptom flares

	Ulcerative Colitis
	The latest ulcerative colitis news from News Medical

	First-of-its-kind pregnancy hormone test reveals why female IBD patients face severe symptom flares Inflammatory bowel disease (IBD), which comprises the inflammatory conditions Crohn's disease and ulcerative colitis, affects about 1.6 million Americans, many of whom cannot be effectively treated.

	Scientists map how genetic variation drives inflammatory bowel disease Scientists have created the most detailed cell map to date showing how genetic variation influences inflammatory bowel disease (IBD), revealing the specific cells and genes that drive the disease.

			MRM health rewarded a € 2.6 M VLAIO research grant to accelerate the development of novel therapeutics that redefine the treatment of immune-mediated inflammatory diseases MRM Health, a clinical-stage biopharmaceutical company developing therapeutics for immune-mediated diseases, which unlock the power of the microbiome to restore immune balance, today announced that it has been awarded a research grant of € 2.6M from Flanders Innovation and Entrepreneurship (VLAIO), a government organization with the goal to stimulate economic development in Flanders, Belgium.

			Sting signaling stimulates vital immune defenses to actively suppress aggressive tumor growth A new review brings attention to the STING pathway as a critical regulator in both colitis and colon cancer, highlighting its complex and often opposing roles in inflammation and tumor development. The findings underscore how this key component of the innate immune system can act as both a driver of disease and a protective mechanism, depending on biological context.

	Web-based platform facilitates chemical structure queries in metabolomics An international team led by researchers at University of California San Diego and University of California, Riverside has developed a free, web‑based platform designed to make public metabolomics data more accessible.

	Recent advancements in the development of models to study primary sclerosing cholangitis Primary sclerosing cholangitis (PSC) is a rare non-communicable disorder that affects the liver. Chronic inflammation in and around the bile duct is followed by the development of fibrotic obstructions within the duct, causing bile to accumulate within the liver.

	Genetically-modified hookworms successfully deliver medicine to animal hosts Hookworms, intestinal parasites that infect hundreds of millions of people in under-resourced tropical regions around the globe, have evolved to survive inside the human gut for years, secreting molecules that enable co-existence with their hosts.

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