Primary sclerosing cholangitis (PSC) is a chronic, progressive inflammatory disease characterized by fibrosis and bile duct stricturing, which ultimately leads to cirrhosis and liver failure. PSC is strongly associated with both types of inflammatory bowel disease (IBD), namely, ulcerative colitis and Crohn's disease.
A toxin-secreting gut bacterium may fuel ulcerative colitis by killing protective immune cells that maintain intestinal homeostasis, according to a new study. The findings suggest potential for new treatment strategies.
The gut microbiome is made up of trillions of microbes that play a vital role in keeping us healthy. A disturbance in the balance of these microbes can contribute to a variety of health conditions, such as inflammatory bowel disease (IBD).
Potential treatments for one of the world's most dangerous hospital superbugs have been found in a surprising location - hospital toilets.
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