Gut inflammation may explain food sensitivities in IBD patients
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 New study investigates PFAS exposure and future inflammatory bowel diseaseNew study investigates PFAS exposure and future inflammatory bowel disease
 
Exposure to per- and polyfluoroalkyl substances (PFAS), often called "forever chemicals," may play a role in the development of inflammatory bowel disease (IBD) years before symptoms appear, according to a new five-year study supported by a $3.3 million National Institutes of Health (NIH) R01 grant to researchers at the Icahn School of Medicine at Mount Sinai.
 
 
 Gut inflammation may explain food sensitivities in IBD patientsGut inflammation may explain food sensitivities in IBD patients
 
A new study, to be published in Gastroenterology, finds that gut inflammation can change the way gut bacteria break down food - possibly triggering immune reactions to foods that were previously fine to eat.
 
   Antibody patterns may predict inflammatory bowel disease years before diagnosisAntibody patterns may predict inflammatory bowel disease years before diagnosis
 
A large-scale study, presented today at UEG Week 2026, has identified distinct antibody patterns up to 10 years before the diagnosis of inflammatory bowel disease (IBD), potentially opening new avenues for earlier risk detection and providing insights into future disease course.
 
   Transcriptional repression mechanism prevents protective immune pathways from triggering autoimmunityTranscriptional repression mechanism prevents protective immune pathways from triggering autoimmunity
 
A preclinical study by researchers at UT Southwestern Medical Center has discovered how a protein called ZBTB44 helps prevent excessive immune activity that can cause inflammation in the colon, the main section of the large intestine. The findings, published in Nature Immunology, may help explain how immune responses go awry in a range of chronic inflammatory and autoimmune diseases
 
   Blastocystis: Friend or Foe?Blastocystis: Friend or Foe?
 
The role of Blastocystis in gut health is complex, linked to microbial diversity and metabolic traits, with implications for intestinal and metabolic health.
 
 New iron deficiency guidelines raise key blood test cutoffs
 
New iron deficiency guidelines raise key blood test cutoffsASH 2026 guidelines redefine iron deficiency diagnosis with higher ferritin thresholds, aiming for better detection and management across diverse populations.
 
 
 Nearly one in three women with autoimmune diseases waited at least four years for a diagnosis, survey finds
 
Nearly one in three women with autoimmune diseases waited at least four years for a diagnosis, survey findsAn international study of 6,607 adults with autoimmune diseases found that female participants reported longer diagnostic delays, more clinician visits, and higher rates of perceived psychiatric and psychosomatic misdiagnoses than males.
 
 
 Scientists discover water-triggered reactions that may explain microplastic harm
 
Scientists discover water-triggered reactions that may explain microplastic harmResearchers found that six common types of microplastics spontaneously generate reactive oxygen species at their interfaces with water, with more hydrophobic plastics showing greater chemical activity. Laboratory experiments also linked these surface properties to biomolecular adsorption, protein aggregation, and mouse red blood cell damage, although the implications for human health remain uncertain.
 
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