For years, researchers have been hoping for vaccines that protect people against not just one strain of HIV, but every strain of the quickly mutating virus.
People with opioid use disorder (OUD) are at increased risk of contracting human immunodeficiency virus (HIV). While there are effective interventions that can substantially reduce HIV incidence and opioid overdose, like pre-exposure prophylaxis (PrEP) and medications for opioid use disorder (MOUD), many patients still face barriers to accessing and staying engaged in care.
For many people living with HIV, today's treatments can suppress the virus and dramatically improve health. But even when HIV is controlled, damage to the gut caused by the disease can persist, fueling chronic inflammation linked to serious health problems.
Over half of the people carrying HIV experience chronic pain at some point, which is difficult to treat. In a new JNeurosci paper, Hui-Lin Pan, from The University of Texas MD Anderson Cancer Center, and colleagues used mice to explore how HIV leads to chronic pain.
While data from the Centers for Disease Control and Prevention (CDC) show that the total number of U.S. cases of three sexually transmitted infections (STIs) declined from 2022-24, infection rates remain 13% higher than a decade ago. CDC provisional data show more than 2.2 million U.S. cases of chlamydia, gonorrhea, and syphilis were reported in 2024.
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