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The latest cholesterol news from News Medical |
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 | | |  Why pulses could play a bigger role in healthy and sustainable diets A narrative review finds that pulses may support gut and metabolic health through their fiber, protein, phytochemicals, and interactions with the gut microbiota, while offering a lower environmental footprint than many animal protein sources. Human evidence is strongest for selected cardiometabolic outcomes, while many microbiome and fermentation-related benefits remain supported mainly by animal and laboratory studies. | | | | |  Study links dietary fructose to aggressive spread of ovarian cancer A new study from The Wistar Institute has uncovered an unexpected link between fructose - a common dietary sugar - and the spread of an aggressive form of ovarian cancer. | |
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|  | | | | |  Genetic analysis of 1 million people points to FNIP1 as a promising metabolic target Mega-scale exome sequencing of 1,032,116 people identified 59 independent genes linked to the TG:HDL ratio, including 44 rare-coding associations not detected in the previous largest analysis. Ultra-rare FNIP1 loss-of-function variants were associated with favorable fat distribution, lower liver fat and glycemia, and around 60% lower odds of a composite cardiometabolic disease outcome. | |  | | | | |  Blood filtration method helps clear circulating lipids and toxic microplastics The machine is not new. Some version of it has run in hospital treatment rooms for about four decades, drawing blood from one arm, separating out the plasma, passing it across a filter or an adsorber, and returning it to the other arm. | | | | | | |  Perilla oil may curb platelet reactivity and inflammatory signaling in smokers An eight-week randomized trial found that daily perilla oil increased plasma and red-cell ALA, plasma EPA, and platelet closure time in healthy smokers. Perilla oil also reduced TNF-α and TBX21 gene expression, but it did not improve broader coagulation, lipid, endothelial, or postprandial markers. | |
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| | | | A University of Oklahoma researcher has received a five-year, $2 million grant from the National Cancer Institute to investigate how pancreatic cancer uses cholesterol to survive chemotherapy. | | | | |  Insilico Medicine, a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, today announced the nomination of ISM0900, a potent, AI-driven, highly selective, orally available small molecule inhibitor of lipoprotein(a), or Lp(a), as a preclinical candidate (PCC) for the management of cardiovascular risks. | | | | |  A growing body of evidence is reshaping how scientists and clinicians understand the role of cancer metabolism, placing the enzyme HMGCR at the center of a rapidly evolving therapeutic landscape. | | | | | Researchers from Trinity College Dublin and St. James's Hospital have shown that dexamethasone, a commonly prescribed anti-inflammatory steroid, can reduce harmful inflammation triggered by Mycobacterium avium without weakening the ability of human immune cells to control the infection. | | | | | Previous studies have examined the associations between adherence to LS7 and cognitive outcomes, with findings suggesting that higher LS7 scores are associated with better cognitive performance, reduced dementia risk and improved brain health. | | | | | Stem cell therapies have expanded rapidly, with more than 115 clinical trials involving over 1,200 patients approved by late 2024. The U.S. Food and Drug Administration (FDA) recently approved Ryoncil (remestemcel‑L) for children with steroid‑refractory acute graft‑versus‑host disease, signaling a major shift toward routine clinical use. | |
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