Preclinical models map genetic changes behind multiple sclerosis nerve damage

	Multiple Sclerosis
	The latest multiple sclerosis news from News Medical

	Preclinical models map genetic changes behind multiple sclerosis nerve damage More than 1 million people across the United States live with multiple sclerosis (MS), a disease that affects the brain, optic nerves and spine.

	Ocrelizumab slows disability progression in advanced progressive multiple sclerosis A major international phase III clinical trial, led by Queen Mary University of London, has found that ocrelizumab – a medication already prescribed to some patients with MS – significantly slows disability progression in people with primary progressive multiple sclerosis (PPMS), including older patients and those with more advanced disease who are wheelchair users.

			New study shows how exercise hormone reduces multiple sclerosis symptoms A new study offers clues as to why exercise can improve neurological symptoms in people with multiple sclerosis (MS).

			Blood proteins can predict multiple sclerosis years before diagnosis A new study has revealed a group of blood proteins, that are altered in people who go on to develop multiple sclerosis (MS), in some cases more than a decade before diagnosis.

	Miniature lab grown circuits unlock hidden recovery paths for paralysis Cambridge scientists have grown miniature circuits in the lab that mimic how the brain and spinal cord connect up, which underlies our movements. They used this model to show how damage to these connections previously considered 'irreversible' could, in fact, be reversible.

	Research identifies significant spike in neurological disorders during the covid-19 pandemic In 2021, neurological diseases affected 3.40 billion individuals worldwide, corresponding to 43.1 % of the global population. In China, rapid demographic shifts and lifestyle changes have contributed to a continued rise in the burden of stroke, dementia, and Parkinson's disease-a trend expected to persist.

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