Small-molecule drug improves brain performance in mouse model of Rett syndrome
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  August 16, 2017  
  Huntington's Disease  
  The latest huntington's disease news from News Medical  
 Small-molecule drug improves brain performance in mouse model of Rett syndromeSmall-molecule drug improves brain performance in mouse model of Rett syndrome
 
After learning that a small-molecule drug improves breathing in a mouse model of the neurodevelopmental disorder Rett syndrome, University of Alabama at Birmingham researcher Lucas Pozzo-Miller, Ph.D., wondered if he could test it on other brain functions.
 
 
 Expert highlights CRISPR’s applications, limitations, and ethical concernsExpert highlights CRISPR’s applications, limitations, and ethical concerns
 
"Good morning, doctor, I am here for my gene editing appointment." In the future, could this be a greeting heard in physician offices around the world? With the introduction of CRISPR technology, genetic material can now be more easily and precisely edited, even creating changes that can subsequently be inherited by offspring.
 
   Dendritic-specific Golgi plays key role in early neuropathy of degenerative brain diseaseDendritic-specific Golgi plays key role in early neuropathy of degenerative brain disease
 
A joint research team of DGIST have identified the early neuropathic mechanism of polyglutamine brain disease, one of the representative degenerative brain diseases, and suggested a way to restore.
 
 iPSC Applications
 
iPSC ApplicationsThe need for more information regarding the role of the system in the progression of the diseases creates difficulty in treating many diseases. This establishes a need for modeling diseases, which helps to develop the treatment for the disease focusing on the major root cause.
 
 
 New version of gene editing technique corrects molecular mistakes in RNA-based diseases
 
New version of gene editing technique corrects molecular mistakes in RNA-based diseasesUntil recently, the CRISPR-Cas9 gene editing technique could only be used to manipulate DNA. In a 2016 study, University of California San Diego School of Medicine researchers repurposed the technique to track RNA in live cells in a method called RNA-targeting Cas9 (RCas9).