Using Resting-State Functional MRI for Fine-Grained Mapping of Mouse Brain Functional Connectivity
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  September 24, 2017  
  Huntington's Disease  
  The latest huntington's disease news from News Medical  
 Using Resting-State Functional MRI for Fine-Grained Mapping of Mouse Brain Functional ConnectivityUsing Resting-State Functional MRI for Fine-Grained Mapping of Mouse Brain Functional Connectivity
 
The neuroimaging field has been revolutionized by the resting state functional MRI or rs-fMRI technique, (Biswal et al., 1995), highlighting a major shift towards the notion of combined whole brain functional networks in contrast to the process of identifying isolated functional brain regions triggered by some stimulus paradigm.
 
 
 Potential rare gene mutation could act as predictor for schizophrenia and autismPotential rare gene mutation could act as predictor for schizophrenia and autism
 
Huntington's disease, cystic fibrosis, and muscular dystrophy are all diseases that can be traced to a single mutation. Diagnosis in asymptomatic patient for these diseases is relatively easy - You have the mutation? Then you are at risk. Complex diseases, on the other hand, do not have a clear mutational footprint.
 
   New app uses smartphone camera to provide detailed information about heart healthNew app uses smartphone camera to provide detailed information about heart health
 
Want to know how healthy your heart is? Now there's an app for that. In a proof-of-concept clinical trial, engineers at Caltech, Huntington Medical Research Institute, and USC have demonstrated that the camera on your smartphone can noninvasively provide detailed information about your heart's health.
 
   Scientists directly convert skin cells from healthy adults into motor neuronsScientists directly convert skin cells from healthy adults into motor neurons
 
Scientists working to develop new treatments for neurodegenerative diseases have been stymied by the inability to grow human motor neurons in the lab. Motor neurons drive muscle contractions, and their damage underlies devastating diseases such as amyotrophic lateral sclerosis and spinal muscular atrophy, both of which ultimately lead to paralysis and early death.
 
   Researchers develop model to explore hard-to-study mutations in human genomeResearchers develop model to explore hard-to-study mutations in human genome
 
A team of researchers led by a bioinformatician at the University of California San Diego has developed a method to help determine whether certain hard-to-study mutations in the human genome, called short tandem repeats or microsatellites, are likely to be involved in harmful conditions.
 
 New method to 'sneak' biological drugs into brain cells offers hope to cure neurological diseases
 
New method to 'sneak' biological drugs into brain cells offers hope to cure neurological diseasesThe treatment of brain diseases is on the verge of a breakthrough. Researchers from Aalborg University are developing a new method that 'smuggles' medicine past the brain's defense systems, giving hope that diseases such as Alzheimer's can one day be cured.
 
 
 IMB researchers make breakthrough in understanding origin of aging process
 
IMB researchers make breakthrough in understanding origin of aging processResearchers at the Institute of Molecular Biology in Mainz, Germany, have made a breakthrough in understanding the origin of the aging process. They have identified that genes belonging to a process called autophagy - one of the cells most critical survival processes - promote health and fitness in young worms but drive the process of aging later in life.