Study shows why an apple a day may work differently for different people
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 Large US study finds never-married adults face higher risk for most major cancersLarge US study finds never-married adults face higher risk for most major cancers
 
A large US population-based study found that never-married adults had higher cancer incidence than ever-married adults across most cancer types, with the largest disparities seen in older adults and in Black men. The pattern was especially strong for HPV-related, tobacco-related, and several reproductive cancers, suggesting marital status may act as an important social marker of cancer risk.
 
 
 Study shows why an apple a day may work differently for different peopleStudy shows why an apple a day may work differently for different people
 
A 12-week single-blind trial in 38 Japanese adults found that daily Fuji apple intake did not significantly change overall host metabolic markers, but responses differed by baseline gut enterotype. Participants in the Bacteroidaceae-dominant enterotype showed significant increases in fecal short-chain fatty acids after apple consumption, suggesting that gut microbiota structure may shape functional dietary responses.
 
   Popular sweeteners may impact metabolism across generationsPopular sweeteners may impact metabolism across generations
 
When you choose a diet version of your favorite fizzy drink, you consume non-nutritive sweeteners, which taste sweet but - unlike sugar - contain no calories.
 
   EV-RNAs show promise for IBD diagnosis and treatmentEV-RNAs show promise for IBD diagnosis and treatment
 
A research team led by Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine, has published a comprehensive review in ExRNA that sorts out the diverse roles of extracellular vesicle-associated RNAs (EV-RNAs) in the development and progression of inflammatory bowel disease (IBD).
 
   Microplastics found in human bile may be associated with gallstonesMicroplastics found in human bile may be associated with gallstones
 
Findings show microplastics in bile may trigger cellular senescence, suggesting a link to gallstone disease and highlighting the need for further research.
 
 Parents’ intake of sugar substitutes may influence offspring gut biology, study finds
 
Parents’ intake of sugar substitutes may influence offspring gut biology, study findsA mouse study in Frontiers in Nutrition found that parental sucralose and stevia intake altered gut microbiota, short-chain fatty acids, and gene expression across generations, with sucralose showing the stronger and more persistent effects. The changes were transmitted to offspring not directly exposed to the sweeteners, although several effects were attenuated by the F2 generation.
 
 
 New biomarker predicts prognosis and treatment response in colorectal cancer
 
New biomarker predicts prognosis and treatment response in colorectal cancerDetermining the presence of a protein in non-tumor cells within the cancer microenvironment could be one of the keys to establishing prognosis in patients with colon and rectal cancer.
 
 
 Damon Runyon supports young scientists driving cancer research innovation
 
Damon Runyon supports young scientists driving cancer research innovationThe Damon Runyon Cancer Research Foundation has named 13 new Damon Runyon Fellows, exceptional postdoctoral scientists conducting basic and translational cancer research in the laboratories of leading senior investigators.
 
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