Study links common herbicide to rising early-onset colorectal cancer risk
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 Why do the deadliest cancers still get less NIH research funding?Why do the deadliest cancers still get less NIH research funding?
 
Researchers found that NIH funding for major US cancers does not consistently align with lethality, with highly fatal cancers such as pancreatic cancer and small-cell lung cancer receiving far less funding per estimated death than breast or prostate cancer. The study argues that incidence alone is not enough and that funding decisions should better incorporate mortality, survival, and mortality-to-incidence ratios.
 
 
 Study links common herbicide to rising early-onset colorectal cancer riskStudy links common herbicide to rising early-onset colorectal cancer risk
 
Researchers used DNA methylation-based “epigenetic fingerprints” as proxies for lifelong exposome-related patterns and found that early-onset colorectal cancer was associated with lower Mediterranean diet adherence, lower education, smoking-related signatures, and higher picloram-related exposure signals.
 
   Scientists link poor sleep to decreased chemotherapy response via the gutScientists link poor sleep to decreased chemotherapy response via the gut
 
Sleep deprivation has long been known to weaken the immune system. Now UF Health Cancer Institute researchers have made a startling discovery: The gut microbiota drives changes to the immune system caused by chronic sleep loss. These changes promote cancer progression, disrupt circadian rhythm and weaken the effectiveness of chemotherapy.
 
   Scientists find "hidden" pre-cancer signs in advanced esophageal cancer patientsScientists find "hidden" pre-cancer signs in advanced esophageal cancer patients
 
Scientists have found the strongest evidence to date that a condition known as Barrett's esophagus is the starting point for all cases of esophageal adenocarcinoma – the most common type of esophageal cancer in the developed world – even when telltale signs of this pre-cancerous stage are no longer visible.
 
   Generative AI may help scientists connect the many layers of cancerGenerative AI may help scientists connect the many layers of cancer
 
A Cell Perspective argues that generative AI models could help tackle cancer’s multiscale, multimodal complexity by complementing the Hallmarks of Cancer framework. It proposes that models capable of complex pattern recognition, multimodal fusion, and contextual reasoning could improve cancer detection, biological discovery, and precision oncology, while still requiring rigorous validation and human oversight.
 
 Trial shows durable response with preoperative immunotherapy in bowel cancer
 
Patients with a specific type of bowel cancer who were treated with a short course of immunotherapy before surgery instead of post-op chemotherapy have remained cancer-free after almost three years of follow-up, according to new results from the NEOPRISM-CRC clinical trial led by a team from UCL and UCLH.
 
 
 Long-term exposure to air pollution (PM2.5) raises risk of developing cancer by 11 % and of dying from cancer by 12 %
 
Long-term exposure to air pollution (PM2.5) raises risk of developing cancer by 11 % and of dying from cancer by 12 %The Union for International Cancer Control (UICC), with support from the Clean Air Fund, has released a global report, Clean air in cancer control: An overview of the evidence, presenting data on the scale of cancer risk and mortality from polluted air.
 
 
 Newborns carry antibiotic resistance genes within first hours of life
 
Newborns carry antibiotic resistance genes within first hours of lifeAntibiotic resistance genes (ARGs) – segments of DNA that help bacteria survive the effects of antibiotics – can be present in newborns within the first hours of life, according to research presented at ESCMID Global 2026.
 
 
 Three essential biomarkers for measuring immune activation
 
Three essential biomarkers for measuring immune activationAccurate measurement of HMGB-1, neopterin and sIL-2R supports reliable assessment of immune activation across clinical and research applications.
 
 
 Coffee impacts the gut-brain axis to improve mood and stress
 
Coffee impacts the gut-brain axis to improve mood and stressNew research from APC Microbiome Ireland, a world leading research centre at University College Cork, has comprehensively explored the mechanisms behind coffee's positive effects on the gut-brain axis for the first time.
 
 
 Chronic wildfire smoke exposure may raise long-term cancer risks
 
Exposure to wildfire smoke was associated with a significantly increased risk of lung, colorectal, breast, bladder, and blood cancer, according to results from a study presented at the American Association for Cancer Research (AACR) Annual Meeting 2026, held April 17-22.
 
 
 Gut microbiome analysis may help detect Parkinson’s before symptoms appear
 
Gut microbiome analysis may help detect Parkinson’s before symptoms appearAnalysis of microbes in the gut can reveal whether a person faces an elevated risk of Parkinson's disease, before they have developed any symptoms, suggests a new study led by University College London (UCL) researchers.
 
 
 Epigenetic changes allow cancer cells to shift identity and survive drugs
 
Epigenetic changes allow cancer cells to shift identity and survive drugsCancer drugs are designed to shut tumors down. But sometimes, in the very act of attacking a tumor, treatment can also help a small fraction of cancer cells become harder to kill. A new study from researchers at the Institute for Systems Biology (ISB) shows that cancer cells may begin escaping therapy much earlier - as the therapy itself triggers a stress response that drives some cancer cells into a temporary drug-tolerant state.
 
 
 Breast milk sugars promote beneficial bacterial balance in infant guts
 
Sugars contained exclusively in breast milk are helping to feed an important balance of bacteria in babies' developing gut microbiomes, a new study has found.
 
 
 Cryopreservation that preserves viability and function across cancer research workflows
 
Cryopreservation that preserves viability and function across cancer research workflowsSee how Bambanker™ supports high post-thaw recovery and reliable downstream performance across tissues, organoids, tumor digests, and more.
 
 
 Visceral fat strongly linked to urinary incontinence in women
 
Visceral fat strongly linked to urinary incontinence in womenThe accumulation of fat in the abdominal region, especially visceral fat (fat that accumulates between organs), significantly increases the risk of stress urinary incontinence in women.
 
 
 Gut microbiome clues may help spot Parkinson’s disease in its earliest phase
 
Gut microbiome clues may help spot Parkinson’s disease in its earliest phaseResearchers found that a Parkinson’s disease-related gut microbiome pattern appears not only in people with diagnosed Parkinson’s, but also in some non-manifesting GBA1 variant carriers and a subset of healthy individuals. The findings suggest that gut microbiome changes may help flag people who are closer to Parkinson’s disease development, although longitudinal studies are still needed to confirm predictive value.
 
 
 Rising colorectal cancer rates in young Swiss adults spark concern
 
Rising colorectal cancer rates in young Swiss adults spark concernWhile the incidence of colorectal cancer is decreasing among those over 50, it is rising at an alarming rate among younger individuals, sometimes as early as their thirties.
 
 
 APC-deficient cancer cells rely on single enzyme for survival
 
APC-deficient cancer cells rely on single enzyme for survivalA newly published study reports that APC-deficient cancer cells may depend on a single metabolic enzyme for survival, revealing a potential strategy for selectively targeting tumours associated with one of the most common mutations in colorectal cancer.
 
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