New insights explain the Treg paradox in colorectal cancer
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 Scientists map how cinnamon’s bioactives interact with cancer signalingScientists map how cinnamon’s bioactives interact with cancer signaling
 
This review synthesizes preclinical evidence showing that cinnamon-derived compounds can modulate inflammation, oxidative stress, apoptosis, and angiogenesis through multiple cancer-related signaling pathways. While biologically plausible, the findings are largely limited to cell and animal models, underscoring the need for pharmacokinetic, safety, and clinical validation.
 
 
 New insights explain the Treg paradox in colorectal cancerNew insights explain the Treg paradox in colorectal cancer
 
In most solid tumors, high numbers of regulatory T (Treg) cells are associated with poorer outcomes because they dampen the immune system's ability to fight against a tumor.
 
   Blood test identifies colon cancer patients who benefit from anti-inflammatory medicationBlood test identifies colon cancer patients who benefit from anti-inflammatory medication
 
A blood test could help doctors decide which patients with colon cancer should receive anti-inflammatory medication along with chemotherapy after surgery, according to new study in JAMA Oncology.
 
   Frog-derived bacteria offer dual-action anticancer effects and high safetyFrog-derived bacteria offer dual-action anticancer effects and high safety
 
A research team of Prof. Eijiro Miyako at the Japan Advanced Institute of Science and Technology (JAIST) has discovered that the bacterium Ewingella americana, isolated from the intestines of Japanese tree frogs (Dryophytes japonicus), possesses remarkably potent anticancer activity. This groundbreaking research has been published in the international journal Gut Microbes.
 
   Early scans reveal prostate radiotherapy toxicity riskEarly scans reveal prostate radiotherapy toxicity risk
 
Daily scans taken during prostate cancer radiotherapy could be repurposed to guide changes to treatment, reducing the risk of side effects, a study suggests.
 
 Fear strongly influences pain perception in inflammatory bowel disease patients
 
Fear strongly influences pain perception in inflammatory bowel disease patientsPain perception in affected individuals is more strongly influenced by learned fear than in healthy individuals. Changes along the gut-brain axis related to chronic inflammation may explain this.
 
 
 Advances in delivering oxygen-sensitive gut bacteria improve microbial therapies
 
Advances in delivering oxygen-sensitive gut bacteria improve microbial therapiesRecent research has identified practical ways to protect and deliver oxygen-sensitive gut bacteria for a path toward safer, standardized microbial therapies that could reduce reliance on donor-based faecal microbiota transplants.
 
 
 White bread vs wholegrain: which one is actually better for your health?
 
White bread vs wholegrain: which one is actually better for your health?This review dispels common myths about white and wholegrain bread by examining their composition processing and health effects. It concludes that while wholegrain breads offer added benefits white bread remains a safe affordable and nutritionally meaningful staple when fortified.
 
 
 How ultra-processed foods shape Crohn’s disease risk and what dietary strategies can really help
 
How ultra-processed foods shape Crohn’s disease risk and what dietary strategies can really helpThis narrative review synthesizes evidence showing that higher intake of ultra-processed foods is consistently associated with increased Crohn’s disease risk, with mechanistic pathways implicating emulsifiers, carrageenan, maltodextrin, titanium dioxide, sweeteners and salt. It also highlights that minimally processed dietary strategies, including EEN and CDED, show therapeutic promise, particularly in pediatric Crohn’s disease.
 
 
 Revolutionary quantum sensors could enable earlier cancer diagnosis and treatment
 
A revolutionary quantum sensing project that could transform cancer treatment by tracking how immune cells interact with tumors has been awarded a prestigious £2 million Future Leaders Fellowship.
 
 
 New CDC grant supports expansion of colorectal cancer screening across rural Pennsylvania
 
Increasing colorectal cancer screening rates among communities with the greatest need is the goal of a five-year, $4.2 million grant from the Centers for Disease Control and Prevention (CDC) to Penn State College of Medicine.
 
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