Bowel Cancer - Aug 20, 2018 Edition

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	August 20, 2018
	Bowel Cancer
	The latest bowel cancer news from News Medical

Patient on DNA Mismatch Repair Dysfunction

Deficiencies in DNA mismatch repair (MMR) can result in replication errors accumulating across the genome, and lead to disruption of normal cellular function. Microsatellite instability (MSI) can be the first evidence of an MMR deficiency. Learn more about characterizing MSI status by comparing allelic profiles of microsatellite markers.

Read Full Article Here

			Higher circulating vitamin D levels linked with lower colorectal cancer risk A new study authored by scientists from the American Cancer Society, the Harvard T.H. Chan School of Public Health, the U.S. National Cancer Institute, and more than 20 other medical centers and organizations finds that higher circulating vitamin D concentrations are significantly associated with lower colorectal cancer risk.

			Researchers uncover evolutionary history of IBD-associated bowel cancer A team of researchers from Queen Mary University of London have reported the genetic events involved in the early development of bowel cancer in patients with inflammatory bowel disease.

	Using Luminescence to Detect Chemotherapy Response in Patients with Colorectal Cancer Post-operative adjuvant chemotherapy with 5-fluorouracil (5FU)-based regimens have been shown to improve patient outcome after resection of high-risk stage II and stage III colorectal tumors.

	New guidelines recommend people to start colorectal cancer screening at age 45 The American Cancer Society (ACS) and other preventive guideline organizations recommend that screening for colorectal cancer start for people of average risk at age 50.

	Mailing colorectal cancer tests to patients increases screening rates, report researchers Mailing colorectal cancer screening tests to patients insured by Medicaid increased screening rates for this population, report researchers at the University of North Carolina Comprehensive Cancer Center.

	New ACS guidelines recommend early screening for colorectal cancer New guidelines developed by the American Cancer Society recommend that screening for colorectal cancer for average-risk adults begin at age 45, five years earlier than the previous recommendation.

	Study finds how colon cancer alters its genes to escape the immune system A UCLA-led study has found how colon cancer alters its genes during development in order to avoid detection by the immune system, creating a specific genetic imprint in the process.

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