Daily aspirin not reliable for preventing bowel cancer
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 Colonoscopy and FIT at age 60 catch colorectal cancer earlierColonoscopy and FIT at age 60 catch colorectal cancer earlier
 
The SCREESCO trial reveals that colorectal cancer screening at 60 enhances early diagnosis without affecting overall mortality or increasing long-term risks.
 
 
 Daily aspirin not reliable for preventing bowel cancerDaily aspirin not reliable for preventing bowel cancer
 
Daily aspirin use does not offer a quick or reliable way to prevent bowel cancer in the general population and carries immediate risks of serious bleeding, a new Cochrane review finds.
 
   Why Mankai (Wolffia globosa) is emerging as a functional food for metabolic healthWhy Mankai (Wolffia globosa) is emerging as a functional food for metabolic health
 
Mankai (Wolffia globosa) is a high-protein aquatic plant that contains bioactive vitamin B12 and may support metabolic health through diet–microbiome interactions when incorporated into Mediterranean-style dietary patterns. Current evidence highlights promising glycemic, lipid, and gut microbial effects, while emphasizing the need for long-term standalone clinical trials and environmental impact assessments.
 
   Forecasting disease intensity through genomic riskForecasting disease intensity through genomic risk
 
Approximately 60,000 Danes live with chronic inflammatory bowel disease. Some experience limited discomfort, while others go through a debilitating disease course involving surgery and a stoma. Add to this the fear of leaving home due to urgent toilet needs.
 
   Living in deprived neighborhoods reshapes the gut microbiomeLiving in deprived neighborhoods reshapes the gut microbiome
 
This study reveals links between socioeconomic deprivation and gut microbiome changes, highlighting potential pathways to mental and metabolic health issues.
 
 Extra copies of chromosome 1q may play key role in the earliest stages of pancreatic cancer
 
Extra copies of chromosome 1q may play key role in the earliest stages of pancreatic cancerResearchers at the Johns Hopkins Kimmel Cancer Center and its Ludwig Center uncovered new evidence that extra copies of a specific chromosome segment - chromosome 1q - may play a key role in the earliest stages of pancreatic cancer development.
 
 
 New research initiative aims to predict and prevent diseases before they start
 
New research initiative aims to predict and prevent diseases before they startWhat if doctors could tell you a disease was coming years before you felt a single symptom-and stop it in its tracks? That is the goal of a sweeping new research initiative launched by the Icahn School of Medicine at Mount Sinai in collaboration with the Uniformed Services University of the Health Sciences (USU) and the Henry M. Jackson Foundation for the Advancement of Military Medicine (HJF).
 
 
 New test for fecal contamination cuts time for results from 24 hours to 4
 
New test for fecal contamination cuts time for results from 24 hours to 4Scientists at The James Hutton Institute, Scotland’s pre-eminent interdisciplinary scientific research institute for the sustainable management of land, crop and nature resources, have developed a new test that reduces the time required to analyze water samples for indicators of fecal contamination from 24 hours to four.
 
 
 High-dose curcumin fails to produce lasting gut microbiome changes in IBD patients
 
High-dose curcumin fails to produce lasting gut microbiome changes in IBD patientsIn an open-label study of 29 men, including patients with ulcerative colitis and Crohn’s disease in remission, 6 g per day of curcumin for eight weeks led to modest, transient shifts in gut microbiota composition without sustained restructuring. Despite achieving high fecal concentrations and minimal systemic bioavailability, curcumin did not produce durable microbiome changes, and disease activity scores remained stable.
 
 
 Avoiding overcycling in RNA-seq library preparation
 
Avoiding overcycling in RNA-seq library preparationIn RNA-seq library preparation, selecting the appropriate number of PCR cycles is a critical balancing act to avoid overcycling.
 
 
 Study sheds light on behavior of yeast cells in the gut
 
A new study sheds light on the behavior of yeast cells in the gut, paving the way for new lines of yeast that more efficiently produce therapeutic drugs tailored to address specific diseases.
 
 
 Routine terminal ileum intubation and biopsy: A standard practice for colonoscopy completion
 
Terminal ileum intubation is considered the completion step of colonoscopy and is usually performed to assess the ileum.
 
 
 Genomic landscape and clinicopathologic significance of POLE mutant colorectal carcinoma
 
DNA polymerase epsilon catalytic subunit A (POLE) gene plays a crucial role in DNA repair and chromosomal replication.
 
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