Skin Cancer - Study identifies NCOA3 as a novel therapeutic target for melanoma
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  Skin Cancer  
  The latest skin cancer news from News Medical  
 Chaotic genetic changes drive the growth of melanomasChaotic genetic changes drive the growth of melanomas
 
Melbourne researchers have revealed how melanoma cells are flooded with DNA changes as this skin cancer progresses from early, treatable stages through to fatal end-stage disease.
 
   Study identifies NCOA3 as a novel therapeutic target for melanomaStudy identifies NCOA3 as a novel therapeutic target for melanoma
 
For the first time, activation of nuclear receptor coactivator 3 (NCOA3) has been shown to promote the development of melanoma through regulation of ultraviolet radiation (UVR) sensitivity, cell cycle progression and circumvention of the DNA damage response.
 
   Scientists identify new biomarkers in the blood of patients with malignant melanomaScientists identify new biomarkers in the blood of patients with malignant melanoma
 
A team of researchers has studied the molecular profile of small “messenger” vesicles called exosomes, produced by cancer stem cells (CSCs), which play a key role in the process of carcinogenesis and metastasis in the blood of patients with malignant melanoma.
 
 Study shows how melanoma cells evade detection and destruction by immune cells
 
Study shows how melanoma cells evade detection and destruction by immune cellsA dysfunctional immune system significantly contributes to the development of cancer. Several therapeutic strategies to activate the immune system to target cancer cells have been approved to treat different types of cancer, including melanoma.
 
 
 Inhibition of NLRP3 complex can reduce inflammation in melanoma patients
 
Inhibition of NLRP3 complex  can reduce inflammation in melanoma patientsCancer doctors may soon have a new tool for treating melanoma and other types of cancer, thanks to work being done by researchers at the University of Colorado Cancer Center.
 
 
 Study shows how a subset of T cells is generated in melanoma survivors affected by vitiligo
 
Study shows how a subset of T cells is generated in melanoma survivors affected by vitiligoA few patients suffering from melanoma are known to respond quite well to immunotherapy and experience significant and long-lasting tumor regression.