Insights into tumor initiation pave way for new skin cancer treatments
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  December 14, 2018  
  Skin Cancer  
  The latest skin cancer news from News Medical  
 Insights into tumor initiation pave way for new skin cancer treatmentsInsights into tumor initiation pave way for new skin cancer treatments
 
Researchers from VIB and KU Leuven uncovered a key vulnerability of melanoma. While studying the role of the melanoma-specific long non-coding RNA SAMMSON in tumor initiation, the researchers found that it boosts protein synthesis in different cellular compartments. Normal cells are alerted by modification in protein synthesis and react to this threat, but only if this process is altered in one compartment at the time.
 
   Researchers discover natural plant compound that shuts down uveal melanoma cell growthResearchers discover natural plant compound that shuts down uveal melanoma cell growth
 
A natural plant compound exploits a newly identified Achilles' heel in a cancer of the eye, uveal melanoma. In human cancer cells growing in the lab, the compound shuts down the overactive signaling that drives uveal melanoma cell growth, according to researchers at Washington University School of Medicine in St. Louis.
 
   Using molecular targeting approach to kill melanoma cellsUsing molecular targeting approach to kill melanoma cells
 
In 1960, scientists described the "Philadelphia chromosome" that causes chronic myeloid leukemia, and in 2001 the Food and Drug Administration approved the drug imatinib to disable the action of this cancer-causing genetic change.
 
 Natural plant compound exploits newly identified Achilles' heel in uveal melanoma
 
Natural plant compound exploits newly identified Achilles' heel in uveal melanomaA natural plant compound exploits a newly identified Achilles' heel in a cancer of the eye, uveal melanoma. In human cancer cells growing in the lab, the compound shuts down the overactive signaling that drives uveal melanoma cell growth, according to researchers at Washington University School of Medicine in St. Louis.
 
 
 Study: Death rate of melanoma rises for men while for women it falls
 
Study: Death rate of melanoma rises for men while for women it fallsThe rate of men dying from malignant melanoma has risen in populations around the world, while in some countries the rates are steady or falling for women, according to research presented at the 2018 NCRI Cancer Conference.
 
 
 Visual inspection alone is insufficient to diagnose skin cancer
 
Visual inspection alone is insufficient to diagnose skin cancerA Cochrane review of the accuracy of skin cancer diagnostics has found that visual inspection of suspicious lesions is insufficient to ensure an accurate diagnosis.
 
 
 Experts identify emerging frontiers in skin cancer and pigment diseases
 
Experts identify emerging frontiers in skin cancer and pigment diseasesIn a Pigment Cell & Melanoma Research article, world-leading experts identify emerging frontiers in skin cancer and pigment diseases.
 
 
 Researchers identify genes responsible for sun sensitivity and skin cancer vulnerability
 
Researchers identify genes responsible for sun sensitivity and skin cancer vulnerabilityResearch carried out at the Health Sciences department of the Universitat Jaume I of Castellón, Spain, has identified the genes responsible for sun sensitivity and skin cancer vulnerability.
 
 
 Study suggests new strategy to kill melanoma cells
 
Study suggests new strategy to kill melanoma cellsThink of the protein BH3 like a finger that turns off a cancer cell survival switch. The problem is that most cancer cells have found ways to remove this "finger" - commonly, by breaking the action of a gene called p53 that puts the BH3 finger in motion. Now think of Bcl-2 as the switch itself.