High-dose curcumin fails to produce lasting gut microbiome changes in IBD patients
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 Blood markers can indicate people at risk of developing ulcerative colitisBlood markers can indicate people at risk of developing ulcerative colitis
 
Researchers at örebro University have identified blood markers that can indicate who is at risk of developing ulcerative colitis - a chronic inflammatory bowel disease - later in life.
 
 
 High-dose curcumin fails to produce lasting gut microbiome changes in IBD patientsHigh-dose curcumin fails to produce lasting gut microbiome changes in IBD patients
 
In an open-label study of 29 men, including patients with ulcerative colitis and Crohn’s disease in remission, 6 g per day of curcumin for eight weeks led to modest, transient shifts in gut microbiota composition without sustained restructuring. Despite achieving high fecal concentrations and minimal systemic bioavailability, curcumin did not produce durable microbiome changes, and disease activity scores remained stable.
 
   Experts identify safest and most effective diets for IBS managementExperts identify safest and most effective diets for IBS management
 
This review in Nutrients evaluates the scientific evidence, clinical effectiveness, and safety of major dietary strategies for irritable bowel syndrome, including traditional advice, low-FODMAP, gluten-free, Mediterranean, and starch- and sucrose-reduced diets. It concludes that while the low-FODMAP diet has the strongest short-term evidence, no single approach fits all patients, and dietitian-led personalization is essential.
 
 New collaboration explores familial inflammatory bowel disease in Saudi Arabia
 
New collaboration explores familial inflammatory bowel disease in Saudi ArabiaMount Sinai and King Saud University Medical City in Riyadh, Saudi Arabia, today announced a three-year collaboration aimed at better understanding why inflammatory bowel disease (IBD) runs in some Saudi families, and how that knowledge can lead to risk ascertainment, earlier diagnosis and more personalized treatment options.
 
 
 New research initiative aims to predict and prevent diseases before they start
 
New research initiative aims to predict and prevent diseases before they startWhat if doctors could tell you a disease was coming years before you felt a single symptom-and stop it in its tracks? That is the goal of a sweeping new research initiative launched by the Icahn School of Medicine at Mount Sinai in collaboration with the Uniformed Services University of the Health Sciences (USU) and the Henry M. Jackson Foundation for the Advancement of Military Medicine (HJF).
 
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