Omalizumab beats multiallergen oral immunotherapy in multifood allergy trial
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 Stuffed toys can release short-chain PFAS into saliva, study findsStuffed toys can release short-chain PFAS into saliva, study finds
 
Researchers tested 18 stuffed toys and found that all released at least one targeted PFAS into artificial saliva under mouthing-relevant conditions, with PFHxA driving much of the variation between products. Modeled intake of the four PFAS covered by EFSA’s group tolerable weekly intake remained below that benchmark, but some high-PFHxA toys had reduced margins of exposure, and water rinsing produced mixed results.
 
 
 Omalizumab beats multiallergen oral immunotherapy in multifood allergy trialOmalizumab beats multiallergen oral immunotherapy in multifood allergy trial
 
Omalizumab demonstrates higher treatment success for multifood allergies compared to oral immunotherapy, with fewer adverse events impacting patient retention.
 
   Study maps how birth order tracks disease risk across 10 million siblingsStudy maps how birth order tracks disease risk across 10 million siblings
 
Researchers analyzing claims from more than 10 million siblings linked first-born status to higher odds of several neurodevelopmental and allergic diagnoses, while second-born status tracked with substance abuse and gastrointestinal conditions. The observational study identified 150 significant birth-order associations across the phenome, but claims data and residual confounding prevent causal conclusions.
 
   Common allergy medications offer no real relief for eczema patientsCommon allergy medications offer no real relief for eczema patients
 
It's typical for someone looking for relief from dry, itchy, red and irritated skin – also known as eczema or atopic dermatitis – to turn to common allergy medications called antihistamines.
 
   Natural compounds could combat drug-resistant malaria and babesiosisNatural compounds could combat drug-resistant malaria and babesiosis
 
As parasites become increasingly resistant to existing drugs, researchers at the University of California, Riverside are working to develop a new generation of treatments for two serious infectious diseases: malaria and babesiosis.
 
 NIH funds mosquito genetics research to curb deadly disease spread
 
NIH funds mosquito genetics research to curb deadly disease spreadMosquito-borne pathogens, including zika, yellow fever and other illnesses have serious and worldwide impacts on human health.
 
 
 Perilla oil may curb platelet reactivity and inflammatory signaling in smokers
 
Perilla oil may curb platelet reactivity and inflammatory signaling in smokersAn eight-week randomized trial found that daily perilla oil increased plasma and red-cell ALA, plasma EPA, and platelet closure time in healthy smokers. Perilla oil also reduced TNF-α and TBX21 gene expression, but it did not improve broader coagulation, lipid, endothelial, or postprandial markers.
 
 
 NIH awards $2.4 million to study how maternal viral infections reprogram fetal immune development
 
NIH awards $2.4 million to study how maternal viral infections reprogram fetal immune developmentThe National Institute of Allergy and Infectious Diseases of the National Institutes of Health has awarded a new, five-year $2.4 million R01 grant to Dr. Jiahui Ding, assistant professor of obstetrics and gynecology at the Wayne State University School of Medicine's C.S.
 
 
 Study questions antihistamine use for managing eczema symptoms
 
Study questions antihistamine use for managing eczema symptomsAdding oral antihistamines to existing eczema treatments is unlikely to lead to clinically important reductions in eczema and itch severity, and may not reduce sleep disturbance or flare-ups, finds a review of the latest trial evidence published by The BMJ today.
 
 
 Microneedle patches turn skin into a window for immune bioanalysis
 
Microneedle patches turn skin into a window for immune bioanalysisResearchers combined local restimulation of skin-resident memory T cells with hydrogel-coated microneedle patches to recruit and sample rare immune cells. In mouse models, the approach recovered more antigen-specific T cells than a blood sample or punch biopsy, while studies in humans supported short-term tolerability and proof-of-concept cell sampling.
 
 
 Study shows how solid food shapes immune system development
 
In a mouse model, LMU researchers have discovered a signaling pathway through which diet influences the development of the immune system.
 
 
 Mouse study links leaky gut to severe food allergies
 
A "leaky gut" might increase the severity of food allergies, according to new research conducted in mice and published in The Journal of Immunology.
 
 
 Genetic study explains global spread of invasive longhorned ticks
 
The Asian longhorned tick, Haemaphysalis longicornis, spreads serious pathogens, including severe fever with thrombocytopenia syndrome (SFTS) virus, Rickettsia, and Theileria, and its bite can cause a meat allergy in humans.
 
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