Slow and steady wins: Low-dose peanut immunotherapy safely desensitizes 82% of preschoolers in landmark trial

	Allergy
	The latest Allergy news from News Medical

	Slow and steady wins: Low-dose peanut immunotherapy safely desensitizes 82% of preschoolers in landmark trial A Swedish randomized trial found that slow up-dosing peanut oral immunotherapy with a low maintenance dose helped 82% of preschool children achieve sustained peanut tolerance after three years. The approach proved safer than conventional protocols, with severe reactions uncommon and strong family adherence throughout treatment.

	Climate change increases stroke risk through extreme weather and pollution The World Stroke Organization is warning that climate change poses an escalating threat to brain health, with extreme heat in particular increasing the risk of having a stroke and of patients dying from stroke.

			What labs need to know about PFAS and ultrapure water quality This interview with PFAS specialists reveals how ultrapure water impacts lab accuracy.

			Understanding exercise intolerance and low fitness levels Exercise tolerance reflects the ability to sustain physical activity and is influenced by cardiovascular, pulmonary, and metabolic function.

			Brain pathways shape distinct itch responses in the face and body In a new study, researchers from North Carolina State University show that itch sensations in the face are perceived differently from those in the body due to differences in signaling between trigeminal (located in the brain) and spinal pain pathways.

			Silicosis remains widespread among mineral miners worldwide Researchers from National Jewish Health conducted what is believed to be the largest systematic review of silicosis in mineral miners.

	Validation and qualification in the 2022 EU GMP Annex 1 revision An overview of the validation and qualification requirements introduced in the 2022 EU GMP Annex 1 revision, with a focus on sterile manufacturing and contamination control.

	Cruise ship-linked hantavirus cases highlight zoonotic infection risks The Global Virus Network (GVN), representing eminent human and animal virologists from more than 90 Centers of Excellence and Affiliates in over 40 countries dedicated to advancing research, collaboration, and pandemic preparedness, is closely monitoring reports of a hantavirus cluster linked to a cruise ship traveling in the Atlantic, which has resulted in multiple severe cases and fatalities.

	Daily peanut exposure shows success in treating toddler allergies Researchers at Karolinska Institutet have successfully treated children aged 1–3 years with peanut allergies. The children slowly became accustomed to eating peanuts by consuming small amounts of them daily, which were gradually increased over time.

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