Could one amino acid help explain why men tend to live shorter lives?

	Allergy
	The latest Allergy news from News Medical

	Could one amino acid help explain why men tend to live shorter lives? A UK Biobank cohort and Mendelian randomization study involving 272,475 participants linked higher circulating tyrosine with greater all-cause mortality and genetically predicted higher tyrosine with shorter lifespan. After accounting for phenylalanine, the relationship with shorter lifespan was clearest in men, while findings in women were less consistent, suggesting a potential sex-specific role for tyrosine in longevity.

	Study reveals how melanoma weakens skin cell immune defenses Cancers actively remodel their surrounding cells and tissues to create a microenvironment that favors their growth, survival, and spread.

			Tirzepatide vs semaglutide for asthma: the difference was smaller than researchers expected In a US multicenter electronic health record study, researchers compared tirzepatide with semaglutide in adults with asthma and type 2 diabetes, matching 8,176 patients in each treatment group. Asthma exacerbation risk was similar between treatments, while tirzepatide was associated with a lower likelihood of receiving a short-acting beta-agonist prescription.

			Study Reveals How Fungal Enzymes and Clotting Proteins Clog Human Airways Asthma affects more than 300 million people worldwide, and while many can control their symptoms with inhaled steroid medications, about 10% develop a more severe form that does not respond well to these treatments. This steroid-resistant asthma is one of the most difficult forms of the disease to manage.

	Bacteria found in classroom dust may affect children’s respiratory health Common bacteria found in classroom dust are associated with reduced lung function in children according to research presented at the European Respiratory Society (ERS) Congress in Barcelona, Spain.

	New biologic therapy significantly reduces COPD flare-ups in trials Two international clinical trials led in part by researchers at the University of Pittsburgh School of Medicine found that the investigational biologic therapy tozorakimab significantly reduced chronic obstructive pulmonary disease (COPD) flare-ups among patients already receiving standard treatment for the disease compared to patients only receiving standard treatment.

	New method based on human blood simplifies mRNA drug development mRNA-based drugs are emerging as the drug of the future for a wide range of diseases, but they are difficult and time-consuming to develop.

	Nanoparticle platform reliably detects true cases of antibiotic allergy A multidisciplinary scientific team at the University of Malaga has developed a new technology based on magnetic nanoparticles that enables precise, rapid and reliable diagnosis of allergy to beta-lactam antibiotics, including amoxicillin and other penicillins.

	Skin microbiome changes may predict infant eczema and food allergies The first clues that a baby may develop eczema or food allergies could be hiding in the microscopic organisms living on their skin, according to a study led by researchers in Washington State University's College of Veterinary Medicine.

	Children's Colorado launches new program to expand treatment options for children with food allergies Children's Hospital Colorado's Allergy and Immunology Center today launched its Sublingual Immunotherapy Program at its Anschutz Medical Campus in Aurora, expanding treatment options for children with certain food allergies.

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