| A new narrative review led by researchers at UCL and Birmingham Children's Hospital has found there is a lack of evidence to demonstrate the effective use of continuous glucose monitors (CGMs) in people not living with diabetes (PNLD). | |
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| GLP-1 receptor agonists promote the feeling of fullness before eating via neurons in the dorsomedial hypothalamus, according to a new study. The findings offer new insights into the neural pathways by which GLP-1 receptor agonists increase the feeling of fullness to prevent overconsumption of food, which is key in mitigating obesity. Glucagon-like-peptide-1 (GLP-1) plays an important role in signaling the feeling of fullness after eating. | |
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| Researchers at Baylor College of Medicine, the University of Cambridge in the U.K. and collaborating institutions have shown that serotonin 2C receptor in the brain regulates memory in people and animal models. | |
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| Early puberty is associated with increasing odds of chronic disease, both physical and mental. Menarche at 10 vs 11 years, for instance, roughly doubles the odds of long-term ill-health in adult life. The earlier the age at menarche, the greater the odds of stress and ill-health. | |
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| Researchers investigated populations of regulatory T cells, a type of white blood cell, in various tissues. | |
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| When it comes to managing blood sugar levels, most people think about counting carbs. But new research from the University of British Columbia shows that, for some, it may be just as important to consider the proteins and fats in their diet. | |
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| Microscopic changes in the liver can be used to predict if, and where, pancreatic cancer may spread in the body. | |
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| Transgender women are still at risk for prostate cancer. A new study led by Cedars-Sinai Cancer investigators, published in the peer-reviewed Journal of the American Medical Association, concludes that current screening guidelines could miss early-stage prostate cancer in transgender women on hormone therapy. | |
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| Researchers at Weill Cornell Medicine with an international team have used liver biopsies to identify cellular and molecular markers that can potentially be used to predict whether and when pancreatic cancer will spread to an individual's liver or elsewhere, such as the lung. | |
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| Scientists have generated a comprehensive map of the gene targets regulated by the transcription factors HNF4A and HNF1A in human pancreatic beta cells and liver cells. Published in the journal Nature Communications, the study revealed common and tissue-specific molecular pathways regulated by HNF4A and HNF1A, two proteins that possess important functions governing the development and function of the pancreas and liver. | |
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| Memory regulation in humans and animal models is regulated by the serotonin 2C receptor in the brain, according to research from Baylor College of Medicine, the University of Cambridge in the United Kingdom, and affiliated institutions. | |
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| Researchers at Baylor College of Medicine, the University of Cambridge and collaborating institutions have discovered that alterations in the human gene TRPC5 cause obesity and postpartum depression. | |