Endocrinology - Hormone-resistant prostate, breast cancers added to clinical trial of experimental DNA therapy
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   Hormone-resistant prostate, breast cancers added to clinical trial of experimental DNA therapyHormone-resistant prostate, breast cancers added to clinical trial of experimental DNA therapy
 
The Republic of Belarus Ministry of Health has approved expanding the ongoing clinical trial of CureLab Oncology's Elenagen, an experimental DNA therapy, to include two new arms: 1) hormone-resistant breast cancer; and 2) hormone-resistant metastatic prostate cancer.
 
   UVA researchers overturn conventional wisdom on action of key hormone receptors within cellsUVA researchers overturn conventional wisdom on action of key hormone receptors within cells
 
Researchers at the University of Virginia School of Medicine have overturned conventional wisdom on the workings of vital hormone receptors within cells, a finding that could boost drug development for diabetes and related metabolic disorders, cancer and other diseases.
 
 UH researcher set to explore how testosterone works in the brain
 
UH researcher set to explore how testosterone works in the brainMost people have some idea about the hormone testosterone –how it regulates male behavior or how too little of it might cause a decrease in libido and too much might cause aggressive and irritable behavior. Turns out, no one yet knows how testosterone really does all that.
 
 
 Study describes associations between gender-affirming hormone therapy and body weight changes
 
Study describes associations between gender-affirming hormone therapy and body weight changesGender-affirming hormone therapy is the bedrock of medical therapy for many transgender and gender diverse individuals.
 
 
 Study finds no link between menopausal hormone therapy and increased risk of dementia
 
Study finds no link between menopausal hormone therapy and increased risk of dementiaUse of menopausal hormone therapy (MHT, also known as hormone replacement therapy, HRT) is not associated with an increased risk of developing dementia, regardless of hormone type, dose, or duration, concludes a large UK study published by The BMJ.
 
 
 Researchers use embryonic stem cell model to study genetic architecture in the hypothalamus
 
Researchers use embryonic stem cell model to study genetic architecture in the hypothalamusA study led by researchers at Children's Hospital of Philadelphia has implicated several genes involved in a variety of bodily functions associated with the hypothalamus, a notoriously difficult-to-study region of the brain.
 
 
 Pathway preferential estrogens may be a safer alternative to hormone replacement therapy, study shows
 
Pathway preferential estrogens may be a safer alternative to hormone replacement therapy, study showsPostmenopausal women have increased risk of non-alcoholic fatty liver disease due to loss of estrogen from metabolic changes. A high-fat diet further exacerbates the disease, which can progress to cirrhosis and liver failure.
 
 
 Expert to focus on the wonder of hormones that control energy balance and metabolism
 
Expert to focus on the wonder of hormones that control energy balance and metabolismAn exploration of the beauty and wonder of the hormones that control our energy balance and metabolism and how they can be replaced and manipulated to improve human health will be the focus of a lecture celebrating the centenary of insulin by Professor Sir Stephen O'Rahilly at the Royal Society of Medicine on Thursday 2 December 2021.