Just 150 minutes of exercise a week could reverse prediabetes
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 Is aspartame safe for blood sugar? Study answers the big questionIs aspartame safe for blood sugar? Study answers the big question
 
A major systematic review and meta-analysis found that aspartame has little to no effect on blood glucose, insulin, or appetite-regulating hormones in humans. Evidence certainty is very low, with no significant long-term metabolic impact identified.
 
 
 Just 150 minutes of exercise a week could reverse prediabetesJust 150 minutes of exercise a week could reverse prediabetes
 
Engaging in more than 150 minutes of physical activity per week quadrupled the odds of reversing prediabetes to normal glucose levels in Colombian adults. Higher BMI and HbA1c remained strong barriers to reversal, highlighting the power of lifestyle interventions.
 
   Coffee’s hidden compounds could help fight type 2 diabetesCoffee’s hidden compounds could help fight type 2 diabetes
 
A comprehensive review of nearly 150 studies reveals that coffee polyphenols may help regulate blood sugar and reduce inflammation linked to type 2 diabetes. However, most evidence comes from preclinical research, and robust clinical trials are needed to confirm benefits.
 
   Do omega-3 supplements boost athletic performance?Do omega-3 supplements boost athletic performance?
 
Combining omega-3 supplementation with resistance training significantly improved lipid profiles, inflammation markers, antioxidant capacity, and neuromuscular performance in healthy men. While group × time effects weren’t significant, within-group gains suggest real physiological benefits.
 
   Can saffron treat Alzheimer’s and depression?Can saffron treat Alzheimer’s and depression?
 
Saffron shows promise as a natural treatment for depression and cognitive decline, performing as well as standard drugs in clinical trials. However, more rigorous studies are needed before saffron can be recommended in mainstream psychiatric and dementia care.
 
 New pretreatment method boosts islet transplant survival in diabetes
 
New pretreatment method boosts islet transplant survival in diabetesA pretreatment step could help transplanted pancreatic islets survive longer in patients with type 1 diabetes, according to a new preclinical study from Weill Cornell Medicine investigators. One combination of small molecules extended the cells' lives in female mice, and adding two molecules to the mixture boosted cell survival in male mice.
 
 
 Study reveals how FOXA1 mutations drive prostate cancer and therapy resistance
 
A new study from the University of Michigan Rogel Health Cancer Center, published in Science, sheds light on how two distinct classes of mutations in the FOXA1 gene-commonly altered in prostate cancer-drive tumor initiation formation and therapeutic resistance.
 
 
 Working in people-contact roles increase risk of type 2 diabetes
 
Working in people-contact roles increase risk of type 2 diabetesThe emotional demands and confrontation inherent in person-contact roles, involving direct face to face or voice to voice interaction with external parties, are linked to a heightened risk of type 2 diabetes, suggests research published online in Occupational & Environmental Medicine.
 
 
 New guidance helps GPs manage patients using weight loss drugs
 
New guidance helps GPs manage patients using weight loss drugsAcademics at King's College London and the University of East Anglia have released guidance for GPs on how to manage patients who may be privately accessing weight loss drugs.
 
 
 Stress-activated gene damages insulin-producing cells in type 2 diabetes
 
Stress-activated gene damages insulin-producing cells in type 2 diabetesStress does no one - not even your insulin-producing cells - any good.
 
 
 Study shows polar winter challenges men’s muscle mass but not hormone levels
 
Study shows polar winter challenges men’s muscle mass but not hormone levelsResearchers tracked testosterone, cortisol, and body composition in 23 men overwintering at Concordia Station, Antarctica. Despite extreme polar conditions, hormone levels remained stable, though nearly half the crew experienced significant muscle loss.
 
 
 Advancing transdermal insulin delivery through innovative formulation strategies
 
Advancing transdermal insulin delivery through innovative formulation strategiesAnnouncing a new publication for Acta Materia Medica journal. The prevalence of diabetes is increasing and expected to become a major global health burden.
 
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