Biomarkers reveal increase in thyroid cancer incidence among WTC responders

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Biomarkers reveal increase in thyroid cancer incidence among WTC responders

The incidence of thyroid cancer among first responders who volunteered or were employed as firefighters, rescue personnel and cleanup workers at Ground Zero in New York on or after September 11, 2001, is three times higher than that in the general population.

			Research offers molecular details of pancreatic cancer's ability to invade and evade Two known gene mutations induce pathways that enhance pancreatic cancer's ability to invade tissues and evade the immune system.Two known gene mutations induce pathways that enhance pancreatic cancer's ability to invade tissues and evade the immune system. Researchers report the molecular details of this process providing insights into targets for immunotherapies.

			Researchers identify new mechanism for dysfunctional insulin release In a new study, researchers at Uppsala University have identified a previously unknown mechanism that regulates release of insulin, a hormone that lowers blood glucose levels, from the β-cells (beta cells) of the pancreas. This mechanism is disrupted in type 2 diabetes.

	Hormone therapy worsens quality of life in women with breast cancer Analysis of the CANTO cohort published in the journal Annals of Oncology will upset received wisdom on the effects that hormone therapy and chemotherapy have on the quality of life in women with breast cancer.

	Hyperthyroidism and severe hypothyroidism associated with overall unhealthy status, shorter lifespan Herein, the authors show, using wild-type and the Pax8 ablated model of hypothyroidism in mice, that hyperthyroidism and severe hypothyroidism are associated with an overall unhealthy status and shorter lifespan.

	Study examines the utility of thyroid function screening in youth with mood and anxiety disorders A new study from researchers at the University of Cincinnati and Cincinnati Children's looks at the prevalence of abnormal thyroid function in youth with severe mood and anxiety disorder.

	Diabetes data analysis will lead to better blood sugar monitoring and insulin delivery The lives of people with Type 1 diabetes could be significantly enhanced through algorithms that connect glucose monitors and insulin pumps to automatically regulate blood glucose to healthy levels, in the same fashion that cruise control in an automobile regulates speed.

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