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The latest endocrinology news from News Medical |
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 | | |  Semaglutide for weight loss was linked to a sharp drop in alcohol use in this case report A 2026 case report describes a 34-year-old man with obesity and alcohol use disorder whose semaglutide treatment for weight loss was associated with a marked drop in drinking over 10 months, with his AUDIT score falling from 27 to 7 and alcohol use dropping from about 15 drinks per week to half a beer per month. | | | | |  Prickly pear may pack a surprising punch against metabolic syndrome This narrative review examines how Opuntia ficus-indica fruit, or prickly pear, may help target multiple features of metabolic syndrome through its fiber, betalains, polyphenols, carotenoids, and other bioactive compounds. The authors conclude that the fruit shows promising mechanistic and preclinical potential, but stronger human trials are still needed before firm clinical claims can be made. | | | | |  Popular vitamin B3 supplements could weaken cancer therapy effectiveness Millions of Americans take daily supplements-nicotinamide mononucleotide (NMN), nicotinamide riboside (NR) and nicotinamide (NAM)-to boost energy, slow aging and protect the heart and brain. | |
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| | | | | A new study has found that metformin, a widely prescribed diabetes drug, may mimic one of exercise's core biological effects in men with prostate cancer, raising levels of a molecule tied to energy balance and weight control even when patients are inactive. | | | | | Redefining obesity based not only on body mass index (BMI) but on whether excess body fat is causing measurable health problems may complicate diagnosis and delay treatment, according to an Endocrine Society guideline communication published in The Journal of Clinical Endocrinology & Metabolism. | | | | |  Advances in iPSC technology and in vivo reprogramming are expanding the possibilities for cell therapy. Explore the science behind these emerging strategies. | | | | |  The Lancet obesity framework aims to improve risk assessment but risks delaying treatment and deepening health inequities, according to recent evaluations. | | | | | Pancreatic ductal adenocarcinoma is the most common type of pancreatic cancer and has a low five-year survival rate. | | | | | Higher fat content in the pancreas of children and adolescents with obesity is associated with an increased level of heart and metabolic risk factors, including higher than average body mass index (BMI), elevated diastolic blood pressure, higher levels of abdominal and liver fat, and insulin resistance, according to new research presented at this year's European Congress on Obesity (ECO) in Istanbul, Turkey (12-15 May). | | | | |  Tumors driven by cancer-driving KRAS mutations are often susceptible to ferroptosis, a type of cell death that can be harnessed for cancer therapy. | | | | |  Recent research shows that tumors in different organs host microbial communities capable of influencing cancer biology, immune responses, and the effectiveness of therapies, highlighting the need to standardize methods for studying intratumoral microbes. | | | | |  Neuroendocrine cells are unique in their ability to act both as nerve cells and hormone-making cells. | | | | |  Metformin raised the exercise-linked metabolite Lac-Phe in prostate cancer patients across disease stages and treatment settings, while Lac-Phe itself did not predict anticancer response. Patients in the BIMET-1 metformin arm also showed better weight management during anti-androgen therapy, highlighting a possible metabolic benefit relevant to prostate cancer care. | | | | |  The study identifies pTOS as a key metabolite in appetite suppression, highlighting a gut–liver–brain pathway with implications for obesity therapy. | |
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