Neurology / Neuroscience - Manufacturing a Pipette Measured in Microns and Nanometres
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A Novel Approach to Modeling Neurodegeneration A Novel Approach to Modeling Neurodegeneration

The establishment of reliable disease models is crucial for discovering the pathological mechanisms, evaluating the efficacy of therapeutic interventions, and assessing the safety of drug candidates. Pre-formed fibrils (PFFs) are in vitro formed active fibrils that have "seeding" activity and are capable of continuously recruiting soluble endogenous pathological proteins to form aggregates and finally induce neurodegenerative pathologies.

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    Manufacturing a Pipette Measured in Microns and Nanometres Manufacturing a Pipette Measured in Microns and Nanometres
 
Measuring the electrical capacity of a single cell was the challenge in Dale Flaming’s research at UCSF almost 50 years ago. Flaming designed a pipette puller that could manufacture a pipette measured in nanometers. The company he co-founded, Sutter Instrument, is a leading manufacturer of equipment for cellular physiology today.
 
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   How does the Brain Change as we Age?How does the Brain Change as we Age?
 
Aging cannot be attributed to a single pathway, and the mechanisms surrounding the significant brain changes are less clear.
 
 Study estimates the burden of dementia among older adults in the U.S.
 
Study estimates the burden of dementia among older adults in the U.S.The first nationally representative study of cognitive impairment in more than 20 years has found that nearly one in 10 U.S. adults over age 65 have dementia.
 
 
 Understanding Neurobiology through Proteins
 
Understanding Neurobiology through ProteinsThe emerging field of proteomics has already helped further the field of medical science by identifying potential drug targets for numerous diseases.
 
 
 Using neuroimaging to investigate how petting dogs could help clinicians improve animal-assisted therapy
 
Using neuroimaging to investigate how petting dogs could help clinicians improve animal-assisted therapyIn this interview, News Medical speaks to Rahel Marti, Ph.D. student in the faculty of Psychology at the University of Basel, about her new research, which shows that petting dogs engages the social brain, leading the way for new potentialities in animal-assisted clinical therapy.
 
 
 What are the Clinical Applications of Functional Neuroimaging?
 
What are the Clinical Applications of Functional Neuroimaging?Most people would categorize CAT scans, PET scans, and MRI scans into the same grouping, however, it is important to note that a significant variability exists between these neuroimaging techniques. This article explores the clinical applications of functional neuroimaging.
 
 
 Food for thought: ventral visual pathway has neural populations that respond very selectively to images of food
 
Food for thought: ventral visual pathway has neural populations that respond very selectively to images of foodIn this study, a complete set of human cortical specializations was required that actually reflected the functional organization of the cortex.
 
 
 How is Peripheral Neuropathy Treated?
 
How is Peripheral Neuropathy Treated?Peripheral neuropathy is a condition in which damage occurs to the nerves of the peripheral nervous system, producing numbness, tingling, and pain.