Developing ASOs to treat ALS

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	Neurology / Neuroscience
	The latest neurology news from News Medical

Developing ASOs to treat ALS

Oligonucleotides are being investigated for their therapeutic potential to treat ALS, also known as motor neuron disease. In this webinar, learn more about ASO drug discovery from experts at Charles River and Amylyx Pharmaceuticals.

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Modeling Alzheimer's Disease with PFFs and Cerebral Organoids

Alzheimer′s disease (AD) research hinges on robust disease models. Pre-formed Fibrils (PFFs) offer a promising approach, mimicking the seeding and propagation of pathogenic proteins in both in vivo and in vitro models. Introducing PFFs into cerebral organoids enhances the model’s realism by mimicking AD’s protein pathology.

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Spatial Transcriptomics in Neuroscience and Neurological Disorders

Spatial transcriptomics is a new tool that may prove key to increasing our understanding of tissues and the cellular processes at work in a 3D space. This article describes the basic principles of spatial transcriptomics, alongside its application in neuroscience both cognitively and clinically.

	Ohio State study unveils white blood cells' role in nerve fiber regeneration In a new study, neuroscience researchers at The Ohio State University have discovered a special type of human white blood cell that has the potential to regrow nerve fibers.

	Blood test identifies specific pathologies in frontotemporal dementia, ALS, and PSP In a study with 991 adults, scientists at DZNE show that the most common forms of frontotemporal dementia (FTD) as well as the neurological diseases amyotrophic lateral sclerosis (ALS) and progressive supranuclear palsy (PSP) can be recognized by blood testing.

	Angiotensin receptor blockers found to lower epilepsy risk, new study reveals A recent study published in JAMA Neurology shows that angiotensin receptor blockers, a class of blood pressure drugs, reduce the risk of developing epilepsy, especially in older adults and stroke survivors.

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