How Does Amyloid Formation Impact Neurodegenerative Disease?
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  October 29, 2018  
  Neurology / Neuroscience  
  The latest neurology news from News Medical  
 

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    KeysightHow Does Amyloid Formation Impact Neurodegenerative Disease?
 
A protein is a chain of amino acids and, unlike other polymers, the way this chain is arranged in 3D is often unique. The building blocks of protein structures, which are often referred to as a protein’s secondary structure, are mostly alpha-helical, where this chain of amino acids forms helices, or beta-sheets, where these chains form extended strands that stack to form sheet-like structures
 
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   Researchers develop fibrin-targeting immunotherapy to protect against neurodegenerationResearchers develop fibrin-targeting immunotherapy to protect against neurodegeneration
 
Normally, the blood protein fibrin does not enter the brain. But in several neurological disorders, the blood-brain barrier--which keeps large molecules in the blood from entering the brain--becomes abnormally permeable, allowing fibrin to leak into the brain and trigger inflammation.
 
 Stress can cause memory loss and brain shrinkage finds study
 
Stress can cause memory loss and brain shrinkage finds studyAccording to a new study persistent stress can cause real damage to the brain. It can cause loss of memory as well as shrinkage of the brain matter say researchers. The results of this new study have been published in the latest issue of the journal Neurology this week.
 
 
 Does Herpesvirus Cause Alzheimer's?
 
Does Herpesvirus Cause Alzheimer's?Alzheimer’s disease (AD) is a neurodegenerative disease that progresses over time and autopsies show that hallmarks of the disease include pathological changes to patients’ brain structures, such as neurofibrillary tangles (NFTs) and amyloid deposition.
 
 
 Breathing through the nose improves memory consolidation
 
Breathing through the nose improves memory consolidationThe way we breathe may affect how well our memories are consolidated (i.e. reinforced and stabilized). If we breathe through the nose rather than the mouth after trying to learn a set of smells, we remember them better, researchers at Karolinska Institutet in Sweden report in The Journal of Neuroscience.
 
 
 'Digital brain' recreates protein trafficking in the brain
 
'Digital brain' recreates protein trafficking in the brainResearchers have developed a digital 3D brain demonstrating how the toxic proteins involved in neurodegenerative diseases are transported through the brain.
 
 
 Individuals who walk regularly have reduced risk of severe stroke
 
Individuals who walk regularly have reduced risk of severe strokePhysical activity not only reduces the risk of stroke. Individuals who walk at least 30 minutes a day also have a lower risk of severe stroke, according to a new study in Neurology.
 
 
 Study: Neurons regulating reproductive hormone release have different activity in epileptic mice
 
Study: Neurons regulating reproductive hormone release have different activity in epileptic miceMice with epilepsy have altered patterns of neuron activity in the portion of the brain that controls the reproductive endocrine system, University of Illinois researchers report in a new study. Furthermore, the differences in neuron activity in female mice fluctuate across the reproductive cycle, the team found.
 
 
 Functional brain connections for emotional regulation emerge during infancy
 
Functional brain connections for emotional regulation emerge during infancyResearchers in the UNC Early Brain Development Study tracking the development of the brain's emotion circuitry in infancy found that adult-like functional brain connections for emotional regulation emerge during the first year of life.
 
 
 Growth of early brain circuits may help predict child's intelligence and emotional health
 
Growth of early brain circuits may help predict child's intelligence and emotional healthGrowth rates of brain circuits in infancy may help experts predict what a child's intelligence and emotional health could be when the child turns 4, a new study has found.
 
 
 New molecular interaction governs formation of specific connections between neurons
 
New molecular interaction governs formation of specific connections between neuronsResearchers at VIB and KU Leuven have uncovered a new molecular interaction that governs the formation of specific functional connections between two types of neurons.
 
 
 Scientists reprogram mature inhibitory neurons into dopaminergic cells
 
Scientists reprogram mature inhibitory neurons into dopaminergic cellsAttempting to make dopamine-producing neurons out of glial cells in mouse brains, a group of researchers instead converted mature inhibitory neurons into dopaminergic cells.
 
 
 Study to explore bioethics of brain organoids
 
Study to explore bioethics of brain organoidsResearch scientists around the world are now able to investigate the structural, cellular, and developmental intricacies of the human brain using bioengineered stem cell-based models called organoids.