Neurology & Neuroscience - Maternal blood test reveals prenatal methylation clues linked to autism risk
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Mouse NF-L studies are often constrained by limited sample volume, making longitudinal sampling difficult. Learn how ultra-sensitive, low-volume NF-L measurement supports repeated sampling, preserves valuable mouse samples, and enables translational biomarker research across plasma, serum, and CSF.

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   Maternal blood test reveals prenatal methylation clues linked to autism riskMaternal blood test reveals prenatal methylation clues linked to autism risk
 
Researchers found that maternal plasma cell-free DNA methylation patterns in late pregnancy were associated with later autism diagnosis and maternal obesity in a high-likelihood ASD cohort. The findings suggest cfDNA may offer a minimally invasive way to study prenatal epigenetic changes linked to neurodevelopmental risk, but larger validation studies are needed.
 
   Longer hormone exposure linked to healthier brain aging in womenLonger hormone exposure linked to healthier brain aging in women
 
Research indicates that hormonal therapies and later menopause are associated with increased brain volume and thickness, promoting healthier aging.
 
 What Are Brain-Computer Interfaces and How Do They Treat Neurological Disorders?
 
What Are Brain-Computer Interfaces and How Do They Treat Neurological Disorders?Precision neurostimulation leverages AI and closed-loop feedback, delivering tailored treatments for neurological disorders resistant to traditional therapies.
 
 
 Psychological traits may uncover why Alzheimer’s biology differs between patients
 
Psychological traits may uncover why Alzheimer’s biology differs between patientsIn 822 deceased older adults from ROS and MAP, researchers linked stable psychological traits to multi-omic molecular subtypes of Alzheimer’s dementia using postmortem brain tissue from the dorsolateral prefrontal cortex.
 
 
 Blood metabolites reveal lifestyle links to brain health before dementia
 
Blood metabolites reveal lifestyle links to brain health before dementiaBlood metabolome profiling in dementia-free middle-aged adults linked 14 metabolites to cognition and 22 metabolites to MRI markers of brain health. Lifestyle, clinical factors, medication use and gut microbiota appeared to shape many of these metabolites, with ergothioneine emerging as a notable cognition-linked signal.
 
 
 Researchers eliminate embryonic senescent cells, triggering severe neurovascular flaws
 
Researchers eliminate embryonic senescent cells, triggering severe neurovascular flawsAmong the body's most crucial protective features are the brain barrier systems, including the blood-brain and blood-cerebrospinal fluid (CSF) barriers. These barriers are made of highly specialized cells that allow essential nutrients to enter, yet repel dangerous toxins and pathogens that may be circulating in the bloodstream. Scientists have long known what these barriers do, but less about how they are built during development.
 
 
 U-M Health neurosurgeons complete first human implant of wireless brain computer interface
 
U-M Health neurosurgeons complete first human implant of wireless brain computer interfaceNeurosurgeons at University of Michigan Health completed the first-in-human implant of a Paradromics Inc., wireless brain-computer interface, or BCI, as part of a national clinical trial for patients with difficulty speaking.
 
 
 High-dose DHA reaches the brain but fails to protect memory
 
High-dose DHA reaches the brain but fails to protect memoryHigh-dose DHA effectively increased brain levels in older adults at Alzheimer's risk, but did not lead to cognitive or structural brain health improvements.
 
 
 Scientists unlock molecular structure of key protein linked to cancer, neurological diseases
 
Scientists unlock molecular structure of key protein linked to cancer, neurological diseasesAfter nearly four decades of research, Mayo Clinic scientists have revealed the molecular structures of protein kinase C beta (PKCβ), a key protein linked to cancer and neurological diseases.
 
 
 Brighter daytime light is linked to a lower dementia risk
 
Brighter daytime light is linked to a lower dementia riskThe study finds that greater exposure to daytime light may lower dementia risk, pointing to light's role in enhancing circadian rhythms and cognitive function.
 
 

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