How lipoproteins shape your metabolic health
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 No organ is an island: Genetic study shows unique but interconnected aging markersNo organ is an island: Genetic study shows unique but interconnected aging markers
 
Researchers analyzed genetic underpinnings of biological age gaps in nine organ systems using a large dataset from the U.K. Biobank, revealing organ-specific yet interconnected genetic architectures. Their findings may aid in understanding complex diseases and developing holistic treatments.
 
 
 How lipoproteins shape your metabolic healthHow lipoproteins shape your metabolic health
 
Study provides a comprehensive review of the lipoprotein pathway and its impact on healthy metabolism, highlighting the roles of HDL, LDL, and other lipoproteins in cardiovascular health and disease.
 
   Breakthrough humanized mouse model offers new insights for immunotherapy developmentBreakthrough humanized mouse model offers new insights for immunotherapy development
 
A breakthrough for biomedical research promises new insight into immunotherapy development and disease modeling.
 
   Novel antiviral protein SAMD9L blocks HIV-1 and other lentivirusesNovel antiviral protein SAMD9L blocks HIV-1 and other lentiviruses
 
Researchers discovered that interferon-stimulated SAMD9L restricts HIV-1 and other lentiviruses by inhibiting viral translation and endosomal trafficking, while SAMD9 enhances HIV-1 replication.
 
   White blood cell type identified as important contributor to inflammation in obesityWhite blood cell type identified as important contributor to inflammation in obesity
 
Researchers explored neutrophil involvement in visceral adipose tissue (VAT) inflammation in obesity.
 
 Cellular immunotherapy offers hope for solid tumors
 
Cellular immunotherapy offers hope for solid tumorsEarly findings from a small clinical trial provide evidence that a new cellular immunotherapy approach may be effective in treating metastatic solid tumors. In the trial, researchers from the National Institutes of Health (NIH) genetically engineered normal white blood cells, known as lymphocytes, from each patient to produce receptors that recognize and attack their specific cancer cells.
 
 
 CD22-targeted CAR-T therapy shows promising results in relapsed large B-cell lymphoma
 
CD22-targeted CAR-T therapy shows promising results in relapsed large B-cell lymphomaCAR-T cell therapy, which targets a specific protein on the surface of cancer cells, causes tumors to shrink or disappear in about half of patients with large B-cell lymphoma who haven't experienced improvement with chemotherapy treatments.
 
 
 Neurodevelopment: From embryo to adult brain
 
Neurodevelopment: From embryo to adult brainThe basic definition of neurodevelopment refers to the brain's development of systems or networks responsible for learning, memory, social skills, and overall brain function.
 
 
 Small molecule discovery offers hope for treatment of Angelman syndrome
 
Small molecule discovery offers hope for treatment of Angelman syndromeAngelman syndrome is a rare genetic disorder caused by mutations in the maternally-inherited UBE3A gene and characterized by poor muscle control, limited speech, epilepsy, and intellectual disabilities.
 
 
 Decoding the significance of subnormal liver enzyme activity
 
Decoding the significance of subnormal liver enzyme activityLiver diseases are commonly diagnosed using serum enzyme assays, particularly for aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), gamma-glutamyl transpeptidase (GGT), and 5'-nucleotidase (5'-NT).
 
 
 High ambient temperatures during pregnancy can have detrimental impact on offspring health
 
High ambient temperatures during pregnancy can have detrimental impact on offspring healthAs climate change warms the planet, high ambient temperatures are expected to be more common and intense over the coming decades in the U.S. and worldwide.
 
 
 Stem-like cells found to drive growth of aggressive pediatric brain tumors
 
Stem-like cells found to drive growth of aggressive pediatric brain tumorsA team of researchers at Baylor College of Medicine, Texas Children's Hospital, the Hospital for Sick Children in Toronto and collaborating institutions has identified and located a population of stem-like cells that initiates and maintains Group 3 medulloblastoma (Gr3-MB) in the developing brain.
 
 
 Study shows safety of pulsed field ablation for treating patients with atrial fibrillation
 
Study shows safety of pulsed field ablation for treating patients with atrial fibrillationPulsed field ablation (PFA) is safe for treating patients with common types of atrial fibrillation (AF), according to the largest study of its kind on this new technology, led by the Icahn School of Medicine at Mount Sinai.
 
 
 Early detection of aggressive multiple myeloma through molecular analysis
 
Early detection of aggressive multiple myeloma through molecular analysisMultiple myeloma is one of the most common forms of cancer of the immune cells in the bone marrow. It is considered incurable.
 
 
 Machine-learning model can predict survival of dialysis patients on Continuous Renal Replacement Therapy
 
Machine-learning model can predict survival of dialysis patients on Continuous Renal Replacement TherapyA UCLA-led team has developed a machine-learning model that can predict with a high degree of accuracy the short-term survival of dialysis patients on Continuous Renal Replacement Therapy (CRRT).
 
 
 Study highlights marked increase in iron deficiency among female military recruits
 
Study highlights marked increase in iron deficiency among female military recruitsAfter five months of basic military training, the proportion of female recruits with iron deficiency had more than doubled, from 25% to 55%.