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The latest hematology news from News Medical |
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|  | | | | |  Small T-cell subset drives powerful multiple myeloma immunotherapy responses Researchers from The University of Osaka find that only a small fraction of T cells may drive the robust anti-cancer response seen in breakthrough multiple myeloma immunotherapy. | |  | | | | |  How antibody-drug conjugates are redefining targeted cancer therapy Antibody-drug conjugates are rapidly expanding cancer therapies, with 19 approved globally and many more in development, but their success depends on better targets, payloads, linkers, dosing, and patient selection. The Cell review shows that next-generation ADCs could widen treatment options, but safety, resistance, tumor heterogeneity, and clinical translation remain major barriers. | | | | | | |  Dual-pathway protein degradation approach could improve cancer treatment Targeted protein degradation has become one of the most promising strategies in modern drug discovery, enabling scientists to eliminate disease-causing proteins instead of merely blocking them. | |
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|  | | |  For decades, ultrasound has been associated with diagnostics – a routine scan in a hospital room, a monitor displaying organs, tissues, or the first image of a baby. | | | | |  Researchers have introduced a novel diagnostic method that can more sensitively detect gene fusions in B-cell acute lymphoblastic leukemia (B-ALL), the most common type of pediatric cancer, compared to other publicly available fusion detection algorithms. | | | | |  The review finds that several candidate biomarkers may help estimate fruit and vegetable intake more objectively than self-reported dietary tools, but most remain limited by specificity, sampling burden, supplement use, or incomplete validation. | | | | |  Four new research studies funded by the Ontario Institute for Cancer Research (OICR) will deliver cutting-edge innovations by maximizing the impact of existing research and making the most out of patient contributions. | | | | |  Researchers have introduced a novel diagnostics method that can more sensitively detect gene fusions in B-cell acute lymphoblastic leukemia (B-ALL), the most common type of pediatric cancer, compared to other publicly available fusion detection algorithms. | | | | |  Selecting a clinical microscopy camera requires balancing sensitivity, resolution, and workflow compatibility for consistent pathology imaging. | | | | |  A study reveals that mosaic loss of the X chromosome in blood cells may indicate reduced natural conception likelihood in women, linking fertility and aging. | | | | |  An artificial intelligence-based tool may help physicians determine which newly diagnosed multiple myeloma patients are most likely to benefit from specific therapies, including immunotherapy and stem cell transplantation. | | | | |  Many cases of iron deficiency in school-aged children could be diagnosed earlier, according to a new study published in Blood Red Cells & Iron, a journal of the American Society of Hematology (ASH). | | | | |  A new oral antiviral drug candidate has been developed for the treatment of diseases caused by orthoparamyxoviruses, such as measles and Croup syndrome, according to a study published by researchers in the Center for Translational Antiviral Research at Georgia State University. | | | | | A phase I clinical trial is testing whether a tumor-targeting virus can help immunotherapy work more effectively against aggressive neuroendocrine tumors that often resist treatment. | | | | | Inflammatory bowel disease (IBD), which comprises the inflammatory conditions Crohn's disease and ulcerative colitis, affects about 1.6 million Americans, many of whom cannot be effectively treated. | | | | | Almost all animal species -- including humans -- have blood cells, but between different species our blood tells different stories. | |
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