Autism study shows vitamin D and iron deficiencies affect up to 40% of children

	Hematology
	The latest hematology news from News Medical

	Autism study shows vitamin D and iron deficiencies affect up to 40% of children Researchers in Singapore found that 30–40% of children with autism spectrum disorder have vitamin D or iron deficiencies, regardless of eating habits. Age and ethnicity increased vitamin D risk, while picky eating was not a reliable predictor.

	Gut disorders forecast Alzheimer’s and Parkinson’s risk years before diagnosis Study maps clinical, genetic, and proteomic links between gut-brain disorders and neurodegeneration, showing how diabetes, vitamin D deficiency, and bowel disorders forecast Alzheimer’s and Parkinson’s years in advance. Multimodal models in biobanks highlight early detection and personalized prevention opportunities.

			Stress in mothers causes eczema in newborn mice through immune cell changes Maternal prenatal stress in mice disrupts fetal mast cell programming, triggering eczema-like skin inflammation and heightened sensitivity after birth. The findings reveal how corticosterone-driven immune and neuronal changes in utero may set the stage for pediatric eczema risk.

			New NIH-funded project aims to turn rare HIV cures into broadly applicable immunotherapy Nearly 20 years ago, a man named Timothy Ray Brown who was living with HIV and cancer, underwent two courses of stem cell transplantation to treat his acute myeloid leukemia.

			Next-gen sequencing reveals the regulatory potential of the non-coding genome The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a key player in understanding complex diseases. Following the landmark achievements of the Human Genome Project (HGP), scientists have increasingly focused on deciphering the non-coding regions of the human genome, which comprise approximately 98% of the genetic material.

	Research sheds new light on depression’s biological roots Researchers at McGill University and the Douglas Institute have identified two specific types of brain cells that are altered in people with depression.

	Histamine Intolerance: A Real Condition or Misdiagnosed Food Sensitivity? Histamine intolerance is a proposed condition where impaired histamine metabolism causes wide-ranging symptoms, but evidence remains limited. It overlaps with many disorders, making diagnosis and treatment uncertain.

	High protein diet linked to increased risk of cancer-associated venous thromboembolism Next to cancer recurrence or progression, cardiovascular diseases are the leading causes of death in cancer survivors.

	New method uncovers how extracellular vesicles impact immune response in cancer Certain types of biochemical processes can impair the immune system's ability to recognize and kill cancer cells. Purdue University's W. Andy Tao and his associates have developed a new way to study these processes.

	Can oral bacteria make heart disease worse? The presence of viridans streptococci in coronary plaques indicates a role in atherosclerosis, potentially influencing heart disease outcomes.

	First clinical trial in cats tests targeted therapy for deadly head and neck cancer Researchers have reported results from the first-ever clinical trial of a new class of targeted therapy in pet cats with head and neck squamous cell carcinoma (HNSCC)-a cancer which is notoriously deadly and difficult to treat.

	New core dataset advances standardized care and research in systemic lupus erythematosus The European Alliance of Associations for Rheumatology - has published new recommendations on core datasets to be used in systemic lupus erythematosus (SLE).

	How the Vutara VXL simplifies single-molecule imaging Explore how the Bruker Vutara VXL advances single-molecule imaging across DNA, RNA, and proteins

	Impaired blood flow alters immunity and fuels tumor progression Cutting off blood flow can prematurely age the bone marrow, weakening the immune system's ability to fight cancer, according to a new study from NYU Langone Health.

	Research examines how cancer may invalidate forensic age-estimation tools Patients with solid tumors, including breast and lung cancers, showed only slightly less accurate results. In contrast, individuals with blood cancers, particularly chronic lymphocytic leukemia (CLL) and acute myeloid leukemia (AML), sometimes had large errors, with ages overestimated by as much as 50 years.

	Physician retention in New York reaches highest level in nearly a decade The percentage of physicians who go on to practice in New York State after completing their residency training continues to climb.

	ChronODE method offers precision in timing gene therapy treatments A Yale research team has created a new computer tool that can pinpoint when exactly genes turn on and off over time during brain development - a finding that may one day help doctors identify the optimal window to deploy gene therapy treatments.

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