Scientists identify key genetic events responsible for initiating childhood leukemia
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  April 20, 2018  
  Hematology  
  The latest hematology news from News Medical  
 Scientists identify key genetic events responsible for initiating childhood leukemiaScientists identify key genetic events responsible for initiating childhood leukemia
 
The key genetic events responsible for initiating the early stages of a type of childhood leukemia have been identified by scientists at The Institute of Cancer Research, London. Insights into the ‘founder’ genetic mutation for this type of leukemia, present in all the cancer cells, could be used in the development of new targeted drugs.
 
   FDA grants accelerated approval to leukemia drug for patients with MRD-positive ALLFDA grants accelerated approval to leukemia drug for patients with MRD-positive ALL
 
The U.S. Food and Drug Administration granted accelerated approval to Blincyto (blinatumomab) to treat adults and children with B-cell precursor acute lymphoblastic leukemia (ALL) who are in remission but still have minimal residual disease (MRD).
 
   Cancer risk found to be three times greater after acute thrombosis in the legCancer risk found to be three times greater after acute thrombosis in the leg
 
Patients with the most acute type of thrombosis in the leg - known as an arterial thrombosis - risk developing diseases that are far worse than the blood clot itself. The risk of developing cancer during the first six months after the blood clot is three times greater than normal.
 
 New discovery may offer insight into treating sickle cell anemia and other blood disorders
 
New discovery may offer insight into treating sickle cell anemia and other blood disordersDiscovery by Scripps Research scientists may offer insight into treating blood disorders such as sickle cell anemia.
 
 
 Insights into blood cell formation may help break new ground in treatment of anemia
 
Insights into blood cell formation may help break new ground in treatment of anemiaEvery day, stem cells in our bone marrow produce billions of new red blood cells. Any disruption in this process can result in serious disease. Researchers from Charité - Universitätsmedizin Berlin and Harvard Medical School have succeeded in furthering our understanding of how blood cells are formed.
 
 
 Researchers uncover mechanism critical to keeping blood stem cells functional
 
Researchers uncover mechanism critical to keeping blood stem cells functionalHematopoietic stem cells, that form mature blood cells, require a very precise amount of protein to function - and defective regulation of protein production is common in certain types of aggressive human blood cancers.
 
 
 Research identifies link between rare gene variants and survival after blood and marrow transplant
 
Research identifies link between rare gene variants and survival after blood and marrow transplantBlood and marrow transplant, or BMT, is a lifesaving and effective treatment for many patients, but the procedure can cause serious and life-threatening complications.
 
 
 Researchers fabricate injectable bandage to promote wound healing
 
Researchers fabricate injectable bandage to promote wound healingA penetrating injury from shrapnel is a serious obstacle in overcoming battlefield wounds that can ultimately lead to death.Given the high mortality rates due to hemorrhaging, there is an unmet need to quickly self-administer materials that prevent fatality due to excessive blood loss.
 
 
 Fetal Hemoglobin
 
Fetal HemoglobinFetal hemoglobin (HbF) is the form of hemoglobin that is dominant during fetal life and is also markedly increased in concentration for several weeks after birth.