Estrogen levels in the brain may play a role in women’s risk of stress-related memory problems

	Hematology
	The latest hematology news from News Medical

	Estrogen levels in the brain may play a role in women’s risk of stress-related memory problems Experiencing multiple acute stresses at the same time, as in natural disasters or mass shootings, can leave lasting memory scars.

	Two-pronged therapeutic technology for cancer wins Pfizer Prize for Biomedical Research 2026 Whereas conventional treatments such as chemotherapy and radiotherapy show their limitations in battling certain advanced cancers, immunotherapy and therapeutic vaccines have opened up a new realm of hope for patients.

			Scientists discover a non-classical platelet mechanism linked to severe infections Platelets are small, anucleate blood cells that play an essential role in hemostasis. Their primary task is to recognize vascular injury, become activated, and aggregate via their surface receptor integrin αIIbβ3. This leads to the formation of a stable platelet plug that seals the wound and stops bleeding.

			Herpes virus infection softens cell nuclei through internal mechanical changes A recent international research project has used advanced microscopy techniques and computational modeling to discover why virus infection changes the nuclear structures and biomechanical forces affecting the nucleus.

			How DNA and life experiences leave distinct marks on the human immune system Using single-cell epigenomic profiling of immune cells from 110 individuals, researchers show that genetic variation and environmental exposures shape the human immune system through distinct DNA methylation mechanisms. Genetic effects concentrate within gene bodies of memory cells, while environmental exposures primarily remodel regulatory regions in naive immune cells.

	Color vision deficiency is linked to worse survival in bladder cancer The study highlights how color vision deficiency can delay bladder cancer diagnosis, increasing mortality risk and underscoring the need for targeted screening.

	Study explores how shared cells influence health across generations During pregnancy, maternal and fetal cells migrate back and forth across the placenta, with fetal cells entering the mother's bloodstream and tissues.

	Regulating microglial phagocytosis through immunotherapy could slow Parkinson's disease progression By analyzing tissue from patients with Parkinson's disease, and animal and cellular models of the disease, a research team from the Institut de Neurociències of the UAB has shown that the main immune cells of the brain become reactive and overexpress certain receptors that promote the elimination of dopaminergic neurons, even when these neurons are still functional.

	Shared genetic architecture links schizophrenia with hemispheric white matter microstructure Schizophrenia is a highly heterogeneous psychiatric disorder affecting ~1% of the global population, typically emerging in adolescence or early adulthood and characterized by hallucinations, delusions, disorganized thinking, and cognitive impairments; while its etiology remains elusive, genetic factors are widely recognized as fundamental, and GWAS have identified over 200 genome-wide significant loci.

	Maternal diet after childbirth and its role In postpartum recovery Adequate and healthy nutrition is important during the postpartum time to support wound healing, hormone balance, energy, sleep quality, and stress resilience.

	Three dimensional dataset transforms emergency medical training and robotic assistance Researchers from Tianjin University have introduced the Emergency Medical Procedures 3D Dataset (EMP3D), a pioneering resource that captures the intricate movements of medical professionals during life-saving interventions with unprecedented precision.

	Prognostic nutritional index proposed as prognostic marker in hepatocellular carcinoma The prognostic nutritional index (PNI), calculated from serum albumin and lymphocyte count, reflects a patient's immune-nutritional status and has been proposed as a prognostic marker in hepatocellular carcinoma (HCC).

	Characteristic features of bone marrow metastasis from non-hematolymphoid malignancies Bone marrow metastasis (BMM) from non-hematolymphoid malignancies with resultant cytopenia(s) can mimic primary hematolymphoid disorders. This study aimed to investigate the clinical and pathological characteristics of BMM from non-hematopoietic tumors.

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