|
|
|
| |
|
|
| |
The latest cardiology news from News Medical |
|
|
|
 | | |  Statins may trigger muscle side effects by activating inflammatory danger signals An experimental study in Science Advances shows that statins, primarily fluvastatin in these experiments, may promote low-level muscle myopathy by reducing isoprenoid-dependent protein prenylation rather than by cholesterol lowering. | | | | |  Oral GLP-1 drug elecoglipron helps adults lose up to 11.8% body weight Once-daily oral elecoglipron produced dose-dependent weight loss in adults with obesity or overweight without diabetes, with mean reductions reaching 10.5% at 26 weeks and 11.8% at 36 weeks in the highest-dose weekly-titration group. The phase 2 trial found no evidence of a weight-loss plateau by 36 weeks, while gastrointestinal adverse events were common but generally manageable. | |
|
|
|  | | | | |  Apitegromab helps tirzepatide users lose fat while preserving lean mass A phase 2 trial found that apitegromab plus tirzepatide reduced lean body mass loss by 1.9 kg compared with tirzepatide plus placebo after 24 weeks, while overall weight loss remained similar. | |  | | | | |  GLP-1 medicines may cut clot-related risks in chronically inflamed patients In a target trial emulation using OneFlorida+ electronic health record data, GLP-1 receptor agonist use in adults with obesity and autoimmune disease was linked to lower hazards of pulmonary embolism, venous thromboembolism, stroke/TIA, emergency department visits, and all-cause mortality. | | | | | | |  Obesity drug mazdutide reduces weight and waist size in major trial Once-weekly 9 mg mazdutide produced clinically meaningful weight loss in Chinese adults with obesity, reducing body weight by 16.65% after 60 weeks versus 1.50% with placebo. The phase 3 GLORY-2 trial also found improvements in waist circumference, systolic blood pressure, and lipid markers, but gastrointestinal adverse events were common. | |
|
|
| | | |  Acute cardiac responses to marathon running include biomarker spikes and structural changes, though their long-term impact on heart health needs further study. | | | | |  Higher serum 25-hydroxyvitamin D levels were independently associated with lower LDL-C, triglycerides, and lipoprotein(a) in 773 male professional athletes. The cross-sectional study cannot establish causality, but it suggests that vitamin D status may be linked to cardiovascular risk-related lipid markers, even in elite athletic populations. | | | | |  Researchers developed a soft robotic heart model that replicates HFpEF, enhancing understanding of the disease and supporting innovative treatment strategies. | | | | |  Researchers mapped 442,239 single nuclei from nonfailing human hearts to chart how cardiac cells change from fetal development to older adulthood. The study identified PRDM16 as an age-declining cardiomyocyte regulator, with experimental evidence showing that restoring Prdm16 in aged mouse hearts improved systolic function and partly reversed aging-associated transcriptional patterns. | | | | |  Researchers at RCSI University of Medicine and Health Sciences have developed an artificial model of the mitral heart valve that faithfully mimics the valve's complex mechanical behavior in the human heart. | | | | |  Women who lift weights may have a lower risk of major heart disease, especially when combined with aerobic exercise, according to a new study published today in JACC, the flagship journal of the American College of Cardiology. | | | | |  The American Heart Association and the American College of Cardiology, along with two other leading medical organizations have developed the first-ever guideline aimed at preventing and managing cardiovascular-kidney-metabolic (CKM) syndrome, an interconnected set of health conditions that significantly increase the risk of multiorgan complications and negative cardiovascular outcomes. | | | | |  An international survey has highlighted major gaps in cardio-oncology training, despite its increasing clinical importance. These results were presented at ESC Cardio-Oncology 2026, the second annual conference of the European Society of Cardiology's Council of Cardio-Oncology. | | | | |  A common misperception exists that electrocardiograms (ECGs) simply contain data about heart activity. | | | | |  The cardioprotective effects of heart failure treatments in patients with cancer were demonstrated today in a presentation at ESC Cardio-Oncology 2026, the annual conference of the European Society of Cardiology's Council of Cardio-Oncology. | | | | |  Reducing the damage sustained by the heart during a myocardial infarction remains one of the major challenges in cardiology, even when the blocked coronary artery is reopened in a timely manner. | | | | |  Researchers from Amsterdam UMC have overturned a key assumption in the biological pacemaker field. | |
|
|
|
|
|
|
|
