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The latest cardiology news from News Medical |
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|  | | | | |  Genetic analysis of 1 million people points to FNIP1 as a promising metabolic target Mega-scale exome sequencing of 1,032,116 people identified 59 independent genes linked to the TG:HDL ratio, including 44 rare-coding associations not detected in the previous largest analysis. Ultra-rare FNIP1 loss-of-function variants were associated with favorable fat distribution, lower liver fat and glycemia, and around 60% lower odds of a composite cardiometabolic disease outcome. | |  | | | | |  Study links better midlife vascular health to nearly 13 more dementia-free years A long-term study of 12,409 adults found that a greater burden of diabetes, hypertension, and current smoking in midlife was associated with substantially fewer years lived free of dementia. Adults with none of these risk factors had about 30.1 dementia-free years from age 55, compared with 17.5 years among those with all three, a difference of nearly 13 years. | | | | | | |  Global surveys reveal little progress in tobacco risk awareness over two decades Across 46 countries, adults who smoked showed high awareness that tobacco causes lung cancer but substantially lower knowledge of cardiovascular and secondhand smoke harms. Knowledge changed little overall across two decades, supporting stronger health warnings, mass media campaigns and enforced smoke-free policies. | |
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|  | | |  In a US cohort of 52,971 adults with type 2 diabetes and established atherosclerotic cardiovascular disease, tirzepatide initiation was associated with a lower one-year risk of major adverse cardiovascular events than sitagliptin. The benefit was driven mainly by lower myocardial infarction and all-cause mortality hazards, although the authors cautioned that mortality findings may be influenced by residual confounding. | | | | |  Researchers created an open-access dataset comparing two wrist-worn heart rate monitors with a chest-strap reference during dry-land exercise and swimming. Both smartwatches performed substantially worse underwater, highlighting the challenges water poses to optical heart rate monitoring and providing a resource for future research on aquatic wearables. | | | | |  People with narrowing of the coronary arteries have low-grade, uncontrolled inflammation in the body, even if they are symptom-free and receiving optimal treatment. | | | | |  Congenital heart disease affects approximately two in every 100 newborns globally. But why do they occur? | | | | |  Discover how a minimal-prep LC-MS/MS microsampling assay simplifies empagliflozin analysis, delivering accurate quantitation. | | | | |  Older adults with cardiovascular disease (CVD) often have coexisting cognitive impairment and frailty, conditions that can significantly affect treatment decisions, recovery, independence and quality of life and should be considered as part of an aging-informed approach to care, according to a new American College of Cardiology Scientific Statement published in JACC, the flagship journal of the ACC. | | | | |  In a landmark moment for both the treatment of heart disease and philanthropic support, The Marcus Foundation has awarded the head of USC Stem Cell Center, Chuck Murry, MD, PhD, $28.7 million to advance a clinical trial testing a stem cell-based therapy designed to regenerate damaged tissue after a heart attack. | | | | |  A new study led by researchers at Wake Forest University School of Medicine has found that artificial intelligence (AI) can help clinicians identify signs of heart failure, including a type that is often missed in routine care. | | | | |  Researchers at Indiana University School of Medicine have developed and tested a six-point scoring system that can help identify patients at high risk of internal bleeding in damaged heart muscle after a severe heart attack using explainable artificial intelligence (XAI). | |
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