Discovery of sequence-driven DNA methylation offers new path for epigenetic engineering

	Dermatology
	The latest dermatology news from News Medical

	Discovery of sequence-driven DNA methylation offers new path for epigenetic engineering All the cells in an organism have the exact same genetic sequence. What differs across cell types is their epigenetics-meticulously placed chemical tags that influence which genes are expressed in each cell.

	Breakthrough medium transforms canine stem cells into beating cardiomyocytes In research, induced pluripotent stem (iPS) cells are derived from skin, urine, or blood samples and developed into other cells, like heart tissue, that researchers want to study.

			Young children in Nigeria may be widely exposed to skin lightening products A significant proportion of under 5s in Nigeria may be being exposed to skin lightning products, if the results of a semi-urban community survey are indicative, suggests research published in the open access journal BMJ Open.

			New Cochrane reviews confirm the effectiveness of HPV vaccines in preventing cervical cancer Two new Cochrane reviews show strong and consistent evidence that HPV vaccines are effective in preventing cervical cancer and pre-cancerous changes, especially when given to young people before they are exposed to the virus.

			Study develops highly accurate polygenic risk models tailored for Han Chinese populations Researchers at Academia Sinica have developed the first population-specific polygenic risk score (PRS) models for people of Han Chinese ancestry, achieving unprecedented accuracy in predicting risks for common diseases such as diabetes, heart disease, autoimmune disorders.

	New polygenic risk scores transform disease prediction for Han Chinese populations Researchers at Academia Sinica have developed the first population-specific polygenic risk score (PRS) models for people of Han Chinese ancestry, achieving unprecedented accuracy in predicting risks for common diseases such as diabetes, heart disease, autoimmune disorders.

	New skin-permeable polymer delivers insulin without needles Innovative zwitterionic polymer facilitates insulin absorption through the skin, offering a painless alternative to injections for diabetes management.

	Single-cell RNA sequencing uncovers diverse CD4⁺ T-cell subtypes in pediatric lupus Detailed mapping of CD4⁺ T cells from children with systemic lupus erythematosus (SLE) has revealed distinct immune cell subsets with likely roles in disease pathogenesis, according to a study led by Weill Cornell Medicine investigators.

	Not serious enough to turn on the siren, toddler’s 39-mile ambulance ride still cost over $9,000 Elisabeth Yoder's son, Darragh, was 15 months old in August when he developed what at first looked to his parents like hand, foot, and mouth disease.

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