Scientists discover BRCA links to head and neck cancer risks

	Dermatology
	The latest dermatology news from News Medical

	Scientists discover BRCA links to head and neck cancer risks An international group led by researchers from the RIKEN Center for Integrative Medical Sciences (IMS) in Japan have discovered associations between pathogenic variants of the BRCA 1 and 2 genes and four types of cancer. Published in ESMO Open, the findings expand the potential for personalized medicine to several cancer types that currently have limited treatment options and poor prognoses.

	What are the best alternatives to opioids for chronic pain relief This article examines emerging non-opioid strategies for chronic pain, from targeted ion-channel drugs and anti-inflammatory biologics to neuromodulation, behavioral therapies, and digital pain tools. It highlights how precision, multimodal care may improve pain control while reducing reliance on opioids.

			Aston University bioscientist receives £125,000 to investigate genetic reasons for neurodegeneration Aston University bioscientist Dr John Reynolds has won a £125,000 Springboard grant from the Academy of Medical Sciences (AMS) for research into neurodegeneration caused by a rare genetic disease.

			Study reveals significant gaps in MMR vaccine knowledge among ER patients Measles remains one of the most contagious infectious diseases, spread through coughing and sneezing, with even small declines in vaccination coverage leading to outbreaks. As of 2026, California has reported its highest annual measles case count in seven years. In response to this growing concern, researchers have begun examining gaps in measles-related knowledge and vaccination coverage.

			Brain organoids reveal mutation-specific insights for Rett syndrome Though many studies approach the developmental disorder Rett syndrome as a single condition arising from general loss of function in the gene MECP2, a new study by neuroscientists in The Picower Institute for Learning and Memory at MIT shows that two different mutations of the gene caused many distinct abnormalities in lab cultures.

	Sunlight exposure via windows risks infant dehydration and skin damage Researchers from the Universitat Politècnica de València, the Francesc de Borja University Hospital in Gandia and the La Ribera University Hospital, through the Fisabio Foundation, have found that sunlight passing through windows in homes is neither a safe nor a recommended alternative for preventing or treating neonatal jaundice, a condition affecting more than half of all newborns.

	Three essential biomarkers for measuring immune activation Accurate measurement of HMGB-1, neopterin and sIL-2R supports reliable assessment of immune activation across clinical and research applications.

	What the Health? From KFF Health News: A new CDC nominee, again President Donald Trump this week nominated a former deputy surgeon general who has expressed support for vaccines to lead the Centers for Disease Control and Prevention.

	Superficial skin exposures pose a higher rabies risk than previously thought While it was previously thought that keratinocytes (skin cells) were only passive conductors that allow the rabies virus to pass through, novel research reveals that these cells play a much more active role. The findings of a new study in the Journal of Investigative Dermatology (JID), published by Elsevier, provide direct evidence that keratinocytes can support viral replication and transmit the rabies virus to neurons.

	Sudan accounts for the world’s largest ongoing humanitarian health crisis After three years of war, Sudan now accounts for the world's largest humanitarian crisis, with 34 million people needing aid, 21 million lacking health services, and repeated attacks crippling a medical system already weakened by disease and hunger.

	Registry data and AI can identify high risk populations for skin cancer Healthcare registry data can show early risk patterns for melanoma skin cancer, according to a study from the University of Gothenburg.

	Scientists warn of a silent surge in resistant Aspergillus and Candida An increasing number of fungi are becoming resistant to medication, posing serious risks for patients with weakened immune systems. That is why fifty researchers from around the world, led by Radboudumc, are calling for action against drug‑resistant fungi. Their call has been published in Nature Medicine.

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