Novel gene rejuvenation therapy preserves cell identity while reversing age

	Dermatology
	The latest dermatology news from News Medical

	Novel gene rejuvenation therapy preserves cell identity while reversing age Every organ and tissue progressively loses function and integrity as it ages. In fact, researchers have identified "hallmarks of aging" that not only present specific processes impacted by age, but are also thought of as levers that, if successfully targeted, could help turn back the aging clock and result in tissue rejuvenation.

	Nearly one in three women with autoimmune diseases waited at least four years for a diagnosis, survey finds An international study of 6,607 adults with autoimmune diseases found that female participants reported longer diagnostic delays, more clinician visits, and higher rates of perceived psychiatric and psychosomatic misdiagnoses than males.

			Skin conductance measurements reveal link between insomnia and disrupted fear regulation A new computational model using skin conductance measurements to estimate stress-related emotional arousal found a significant difference in learned fear and safety responses over time between adults with and without insomnia.

			Sex hormones dictate how skin stem cells renew themselves For a long time, differences between females and males were mainly associated with the reproductive organs. Yet organs that have nothing to do with reproduction, such as the skin, can also be shaped by sex.

			New imaging technique detects subtle skin changes in scleroderma patients Scleroderma (systemic sclerosis) is a rare, chronic, autoimmune disease that causes the body to produce too much collagen, leading to the hardening and thickening of the skin and internal organs.

	Does the type of hand sanitizer matter? A study involving 568 people suggests it might In a 72-day randomized trial involving 568 participants in Japan, an experimental hand sanitizer containing ethanol, benzalkonium chloride, and lactic acid was associated with a 40% lower cumulative incidence of upper respiratory symptoms than a commercial ethanol-based sanitizer.

	New study reveals how Candida auris evades antifungal drugs New research has revealed an unexpected new mechanism through which the killer fungus Candida auris is resisting antifungal drug treatment.

	Mosquito saliva study opens new doors for blocking Zika, Dengue, and West Nile infections Mosquitoes do more than simply transmit the viruses they carry: their saliva may actively help these viruses establish infection in the body from the very moment of the bite.

	Chronic Hand Eczema (CHE) is affecting NHS healthcare professionals and can impact patient care, report finds LEO Pharma and the British Skin Foundation (BSF) today launched a new report exploring the impact of Chronic Hand Eczema (CHE) on NHS healthcare professionals (HCPs) and the wider healthcare workforce.

	Perceptions of science and scientists shape partisan views on common vaccines How Americans view science and scientists is strongly associated with whether they think vaccines are safe and effective - and helps explain partisan differences in perceptions of some vaccines, according to a new study led by a team from the Annenberg Public Policy Center (APPC) of the University of Pennsylvania.

	New program helps high-risk children improve sun protection behaviors Children of parents who have melanoma, a serious type of skin cancer that starts in the cells that make pigment, have twice the lifetime risk of developing the disease themselves.

	Could mRNA Vaccine Technology Help Repair Damaged Livers? Research indicates that brief cellular reprogramming and mRNA nanoparticles can enhance liver repair, offering new strategies for acute liver injury recovery.

	Genomic Adaptation Reveals How Candida auris Resists Potent Antifungal Drug Treatments New research has revealed an unexpected new mechanism through which the killer fungus Candida auris is resisting antifungal drug treatment.

	Regular Hot Baths Could Alleviate Common Circulatory Disease A regular soak in a hot bath could help to improve a common painful circulatory disease, with this strategy being studied by researchers at Manchester Metropolitan University, thanks to funding from the British Heart Foundation.

	Balancing Immune Cells May Unlock Hidden Human Regenerative Potential In a study of fingertip regeneration, a team led by JAX Senior Research Scientist James Godwin found that some immune cells in mice can attack and kill cells needed to rebuild bone, while a subset of those same immune cells can protect the bone-making cells and allow regeneration to continue.

	Study Uncovers Sex Specific Coordinated Stem Cell Dynamics in Skin Repair By filming skin stem cells in living mice over five months, researchers at the Université libre de Bruxelles (ULB), in collaboration with the University of Cambridge, have discovered that in females these cells renew the skin in a more coordinated way than in males.

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