A five-year image-based study in people with type 2 diabetes found metformin use was associated with lower odds of developing intermediate age-related macular degeneration. The observational findings suggest a potential protective link but do not establish causation and warrant prospective clinical trials.
Eric Gaier, MD, PhD, and Dean Eliott, MD, of the Department of Ophthalmology at Mass Eye and Ear, a member of the Mass General Brigham healthcare system, are co-authors of a paper published in Ophthalmology Retina, "Substance Use Disorder Interventions and Ophthalmic Outcomes for Injection Drug Use-Associated Endogenous Endophthalmitis."
Diabetic retinopathy develops through complex microvascular damage driven by chronic hyperglycemia, yet traditional risk factors such as disease duration or glycemic control explain only part of individual risk.
The World Health Organization (WHO) is urging countries to accelerate efforts to ensure that millions of people living with cataract can access simple, sight‑restoring surgery – one of the most effective and affordable interventions to prevent avoidable blindness.
The ability to restore light responses in human retinas postmortem offers a novel model for studying retinal recovery and developing vision-restoring therapies.
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