Swapping high-carb snacks for tree nuts cuts food cravings in young adults at metabolic risk
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 White bread vs wholegrain: which one is actually better for your health?White bread vs wholegrain: which one is actually better for your health?
 
This review dispels common myths about white and wholegrain bread by examining their composition processing and health effects. It concludes that while wholegrain breads offer added benefits white bread remains a safe affordable and nutritionally meaningful staple when fortified.
 
 
 Swapping high-carb snacks for tree nuts cuts food cravings in young adults at metabolic riskSwapping high-carb snacks for tree nuts cuts food cravings in young adults at metabolic risk
 
Daily replacement of typical high-carbohydrate snacks with mixed tree nuts for 16 weeks reduced cravings for sweets and fast foods in young adults with early metabolic syndrome risk. This dietary swap improved overall diet quality, measured by the Healthy Eating Index, without increasing body weight or altering short-term glycaemic markers.
 
   What happens to your body when you eat takeaway food too often?What happens to your body when you eat takeaway food too often?
 
This study of 8,556 US adults shows that frequent takeaway food consumption is associated with a higher energy-adjusted Dietary Inflammatory Index and adverse cardiometabolic markers. The findings suggest that reducing takeaway intake and lowering dietary inflammatory potential may improve long-term cardiometabolic health.
 
   Metabolic syndrome affects nearly four in ten US adults as rates climb in older and Black populationsMetabolic syndrome affects nearly four in ten US adults as rates climb in older and Black populations
 
A large NHANES analysis found that nearly four in ten US adults met criteria for metabolic syndrome between 2013 and 2023, with no statistically significant change in overall prevalence. However, prevalence rose significantly among adults aged 60 years and older and among non-Hispanic Black individuals, alongside a significant non-linear increase in hypertriglyceridemia.
 
   What happens to your body during an ultramarathon? New study reveals key metabolic changesWhat happens to your body during an ultramarathon? New study reveals key metabolic changes
 
This study tracked ultramarathon runners across 100 km, 160.9 km, and 230 km events to examine real-world metabolic, hormonal, and muscle stress responses. Severe energy deficits, muscle damage, and heterogeneous hormonal shifts were observed, with the greatest strain seen in the 230 km distance.
 
 Lowering blood sugar reduces heart risk in prediabetes
 
Lowering blood sugar levels halves the likelihood of serious heart problems in people with prediabetes.
 
 
 Glucose-lowering drugs may reduce risk of developing epilepsy
 
Glucose-lowering drugs may reduce risk of developing epilepsyA preliminary study of people with diabetes suggests that use of glucose-lowering GLP-1 drugs may be linked to a lower risk of developing epilepsy. The study was published on December 10, 2025, in Neurology, the medical journal of the American Academy of Neurology.
 
 
 Urine-based microRNA clock predicts biological aging without a blood test
 
Urine-based microRNA clock predicts biological aging without a blood testResearchers developed and validated a non-invasive urinary microRNA aging clock using extracellular vesicle miRNAs from more than 6,000 adults. The model predicts age with about 4 to 5 years error and links accelerated aging signals to type 2 diabetes.
 
 
 How Traditional Chinese Medicine may reshape the gut microbiome to ease insulin resistance in PCOS
 
How Traditional Chinese Medicine may reshape the gut microbiome to ease insulin resistance in PCOSThis review synthesizes evidence that gut microbiota dysbiosis contributes to insulin resistance and symptom severity in polycystic ovary syndrome through impaired barrier function, inflammation, and altered microbial metabolites. It evaluates how Traditional Chinese Medicine may modulate these pathways while highlighting major gaps in clinical validation, safety, and standardization.
 
 
 Glycation stress drives aortic stiffening through oxidative stress and senescence
 
Glycation stress drives aortic stiffening through oxidative stress and senescenceA new research paper was published in Volume 17, Issue 11 of Aging-US on November 14, 2025, titled "Methylglyoxal-induced glycation stress promotes aortic stiffening: putative mechanistic roles of oxidative stress and cellular senescence."
 
 
 High fructose intake increases fatty liver risk
 
High fructose intake increases fatty liver riskExcessive fructose intake from soft drinks is linked to liver damage and NAFLD. Lifestyle modifications are essential for effective prevention and treatment.
 
 
 Specific gut bacterium reduces weight gain and improves metabolic health
 
Specific gut bacterium reduces weight gain and improves metabolic healthThe gut microbiome is intimately linked to human health and weight. Differences in the gut microbiome-the bacteria and fungi in the gut-are associated with obesity and weight gain, raising the possibility that changing the microbiome could improve health.
 
 
 Tau biology expands beyond microtubules to neurodegeneration, metabolism and mental illness
 
An Thought Leaders Invited Review published today in Genomic Psychiatry by Dr. Peng Lei and colleagues presents a sweeping synthesis of tau protein research that fundamentally reframes our understanding of this molecule's dual identity.
 
 
 Single-cell RNA-seq reveals FBLN7's role in adipose tissue fibrosis
 
Single-cell RNA-seq reveals FBLN7's role in adipose tissue fibrosisFibrosis, resulting from excess extracellular matrix (ECM) deposition, is a feature of adipose tissue (AT) dysfunction and obesity-related insulin resistance.
 
 
 Genetic differences in surfactant proteins influence retinopathy of prematurity risk
 
Genetic differences in surfactant proteins influence retinopathy of prematurity riskA new study from the University of Oklahoma suggests that small genetic differences in two proteins – previously known for their role in premature infants' lungs – may also influence how their eyes develop, potentially affecting the risk of retinopathy of prematurity (ROP).
 
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