Are GLP-1 drugs safe for women planning pregnancy?
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 Diabetes cases nearly double in children and teens worldwideDiabetes cases nearly double in children and teens worldwide
 
A dramatic increase in childhood diabetes cases highlights a global health crisis. While mortality declines, the rising incidence demands urgent attention.
 
 
 Are GLP-1 drugs safe for women planning pregnancy?Are GLP-1 drugs safe for women planning pregnancy?
 
A study reveals rising GLP-1 prescriptions in young women, highlighting low contraception use and potential risks for unintended pregnancies and fetal outcomes.
 
   Smoking raises the risk of all subtypes of type 2 diabetesSmoking raises the risk of all subtypes of type 2 diabetes
 
The characteristics of type 2 diabetes vary from patient to patient and it has been proposed that the condition is made up of four subtypes. Now, new research being presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Vienna, Austria (15-19 September) shows that smoking increases the risk of the condition, regardless of subtype.
 
   Researchers reveal why global gains against chronic diseases are stallingResearchers reveal why global gains against chronic diseases are stalling
 
Researchers analysed mortality data from 185 countries and found that while global non-communicable disease (NCD) deaths before age 80 declined from 2010 to 2019, progress slowed compared to 2001–2010. Gains were mainly from drops in heart disease and stroke, but rising burdens from diabetes, cancers, and neuropsychiatric conditions stalled momentum.
 
   Study challenges conventional thinking about the onset of Type 2 diabetesStudy challenges conventional thinking about the onset of Type 2 diabetes
 
A study from The University of Texas at San Antonio Health Science Center indicates that changes in the body that lead to Type 2 diabetes occur long before current diagnostic thresholds for prediabetes are met.
 
 Scientists uncover how amino acids stabilize proteins in solution
 
For decades, amino acids have been added to medical formulations like insulin as stabilizers: these small molecules keep proteins (i.e. larger particles) from interacting in undesirable ways. And for decades, scientists have known that this works – but not why.
 
 
 Genes play an active role in shaping the gut bacteria, study finds
 
Genes play an active role in shaping the gut bacteria, study findsNew research from the University of Sydney's Charles Perkins Centre has found that genes play an active role in shaping the bacteria found in our gut, questioning the idea that gut health is influenced only by diet.
 
 
 Study: Half of adults without diabetes taking weight-loss drug discontinue treatment within a year
 
Study: Half of adults without diabetes taking weight-loss drug discontinue treatment within a yearThe new class of anti-obesity drugs, glucagon-like peptide-1 receptor agonists (GLP-1RAs), is proving remarkably effective at helping individuals lose weight.
 
 
 AI-powered hydrogel dressings transform chronic wound care
 
AI-powered hydrogel dressings transform chronic wound careAs chronic wounds such as diabetic ulcers, pressure ulcers, and articular wounds continue to challenge global healthcare systems, a team of researchers from China has introduced a promising innovation: AI-integrated conductive hydrogel dressings for intelligent wound monitoring and healing.
 
 
 New genetic test redefines diagnosis and management of hereditary pancreatitis
 
New genetic test redefines diagnosis and management of hereditary pancreatitisA new genetic test developed at Mayo Clinic is redefining how clinicians diagnose and manage hereditary pancreatitis.
 
 
 Genetic study shows dual GIPR/GLP1R action curbs binge alcohol use
 
Genetic study shows dual GIPR/GLP1R action curbs binge alcohol useResearchers used drug-target Mendelian randomization to test whether genetically proxied activation of GLP1R and GIPR influences alcohol-related behaviors. They found that GIPR, especially when combined with GLP1R, was linked to lower binge and heavy drinking, healthier food preferences, improved liver markers, and reduced coronary artery disease risk.
 
 
 Repurposed diabetes drugs boost CAR T therapy effectiveness in bladder cancer
 
Repurposed diabetes drugs boost CAR T therapy effectiveness in bladder cancerUrothelial carcinoma (UC) is the second most common genitourinary cancer, leading to over 16,000 deaths a year in the United States. Despite recent advances, the 5-year survival rate for metastatic UC remains around five to ten percent.
 
 
 Female-specific mechanism enhances heat production in brown fat
 
Higher activity of PGC-1α enables brown fat cells in females to thermogenic activity and energy expenditure compared to males, reveals a study conducted in Japan.
 
 
 Gestational diabetes poses substantial cognitive dysfunction risks for both mothers and offspring
 
Gestational diabetes poses substantial cognitive dysfunction risks for both mothers and offspringA new synthesis of global evidence finds that experiencing gestational diabetes during pregnancy is linked with a decline in intellectual function among mothers, and may increase the risk of neurodevelopmental disorders, including autism spectrum disorder and attention-deficit/hyperactivity disorder (ADHD) in children.
 
 
 Individuals taking semaglutide for weight loss experience less food noise than before
 
Individuals taking semaglutide for weight loss experience less food noise than beforeNew research being presented at the Annual Meeting of the European Association for the Study of Diabetes (EASD) in Vienna, Austria (15-19 September) shows that individuals who are taking semaglutide for weight loss experience less food noise than before.
 
 
 Cannabis use may quadruple the risk of developing diabetes
 
Cannabis use may quadruple the risk of developing diabetesCannabis use is linked to an almost quadrupling in the risk of developing diabetes, according to an analysis of real-world data from over 4 million adults, being presented at this year's Annual Meeting of The European Association for the Study of Diabetes (EASD) in Vienna, Austria (15-19 Sept).
 
 
 Weill Cornell Medicine receives $3.4 million NIH grant to study type 1 diabetes development
 
Weill Cornell Medicine has received a four-year, $3.4 million grant from the National Institute of Diabetes and Digestive and Kidney Diseases, part of the National Institutes of Health, for a study of the details and dynamics of the autoimmune process that causes type 1 diabetes.
 
 
 SLIT2 protein levels in the eye and blood linked to cognitive function
 
SLIT2 protein levels in the eye and blood linked to cognitive functionNeurocognitive impairments are classified by pathological changes with potential for destruction of neural tissue. One change known to occur in neurodegenerative disorders is an accumulation of proteins causing pathological damage.
 
 
 Association between depression and diabetes remains the same, regardless of where people live
 
Association between depression and diabetes remains the same, regardless of where people liveThe relative increase in odds of an individual with diabetes developing severe symptoms of depression – and vice versa – is the same, regardless of where they live, a study of over-50s in 18 countries in Europe that is being presented at the Annual Meeting of the European Association for the Study of Diabetes (EASD) in Vienna, Austria (15-19 September) has found.
 
 
 Healthy plant-based diet may lower type 2 diabetes risk while reducing greenhouse gas emissions
 
Healthy plant-based diet may lower type 2 diabetes risk while reducing greenhouse gas emissionsA diet focused on healthy plant-based foods may lower the risk of type 2 diabetes while reducing greenhouse gas emissions, according to a new study by Solomon Sowah and colleagues from the MRC Epidemiology Unit at the University of Cambridge, United Kingdom, published September 16th in the open-access journal PLOS Medicine.
 
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