WHO releases first global guidelines for managing diabetes during pregnancy

	Diabetes
	The latest diabetes news from News Medical

	WHO releases first global guidelines for managing diabetes during pregnancy The World Health Organization (WHO) today released its first global guidelines for the management of diabetes during pregnancy, a condition affecting about one in six pregnancies – or 21 million women annually.

	Tirzepatide reveals a brain signal that predicts returning food preoccupation Researchers implanted electrodes in the human nucleus accumbens to track brain activity during severe food preoccupation in an individual taking tirzepatide. They found that a delta–theta biomarker disappeared during symptom-free periods and re-emerged weeks before relapse, suggesting a possible neural marker of vulnerability to dysregulated eating.

	Study reveals how gestational diabetes disrupts the placenta at the molecular level Gestational diabetes can cause a multitude of complications in the offspring, but to date, the reasons are incompletely understood.

	Maternal obesity raises childhood epilepsy and disability risks, new study shows Higher maternal BMI before pregnancy is linked to increased risks of epilepsy and intellectual disability in young children, even after extensive adjustment for maternal and neonatal factors. Associations with autism spectrum disorder and ADHD disappear after full adjustment, highlighting the potential mediating role of perinatal complications.

			Dash diet cuts diabetes complications by targeting blood pressure kidney health and inflammation The DASH diet supports metabolic health in people with diabetes by improving blood pressure, renal function, lipids, and modest glycemic markers while reducing risks linked to vascular and inflammatory pathways. Its broad nutrient-driven mechanisms also benefit related conditions such as neuropathy, PCOS, and retinopathy, making it a versatile tool for cardiometabolic care.

			Brain recordings reveal short-lived effects of tirzepatide on food cravings A rare glimpse into the brain activity of a patient with obesity and loss of control eating on tirzepatide, marketed as Mounjaro and Zepbound, revealed that the medication suppresses signaling in the brain's "reward center" thought to be involved in food noise – but only temporarily.

			New transplant approach resets the immune system to stop Type 1 diabetes A combination blood stem cell and pancreatic islet cell transplant from an immunologically mismatched donor completely prevented or cured Type 1 diabetes in mice in a study by Stanford Medicine researchers.

			Oral semaglutide delivers real-world drops in blood sugar and weight in diabetes trial Oral semaglutide delivered meaningful reductions in HbA1c and body weight among GLP-1RA-naïve adults with type 2 diabetes in a Dutch real-world cohort. Lipid levels and blood pressure showed only small changes, reflecting modest cardiometabolic effects outside glucose and weight control.

	How oral GLP-1 drugs work for weight loss Discover how next-generation oral GLP-1 therapies are transforming weight management by breaking through the stomach’s toughest barriers and opening the door to powerful, needle-free metabolic treatments.

	Off-label GLP-1 use highlights the cultural pressures driving body anxieties New obesity drugs that were designed to treat diabetes and obesity are increasingly being used off-label by people without these conditions to achieve slimness and social approval rather than health gains. This perspective maps how such pharmacological thinness interacts with stigma, beauty ideals, digital culture, and inequality, and calls for multinational, intersectional research to understand its full impact.

	Are mushrooms more than a low-calorie food? New analysis explains their hidden advantages Whole mushroom consumption shows consistent benefits for cardiometabolic health, lowering triglycerides in self-chosen diets and improving fasting glucose in a single healthy dietary pattern trial. Early evidence also suggests increases in salivary IgA and possible blood pressure improvements, with no adverse biomarker effects reported.

	High protein breakfasts help you feel fuller but do not change how much you eat later High protein breakfasts, whether plant or animal-based, boosted GLP-1 and PYY and modestly reduced appetite compared with a low protein, high carbohydrate meal. Despite these hormonal and appetite changes, lunchtime energy intake remained unchanged in both younger and older adults.

	Automated insulin delivery improves glucose control in pregnant women with Type 1 diabetes An international study co-led by University of Calgary researchers has found new insulin delivery technology helps control glucose levels during pregnancy for those with Type 1 diabetes, which is crucial to the health of women and their newborns.

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