New compounds reduce inflammation without weakening immune defense
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 Sleep apnea raises risk of cardiovascular events and deathSleep apnea raises risk of cardiovascular events and death
 
New research to be presented at this year's European Congress on Obesity (ECO 2026, Istanbul, Turkey, 12-15 May) shows that those living with obstructive sleep apnea (OSA) have a 71% higher risk of cardiovascular events (CVEs) or death from any cause (all-cause mortality) compared with those not living with OSA.
 
 
 New compounds reduce inflammation without weakening immune defenseNew compounds reduce inflammation without weakening immune defense
 
Scripps Research scientists have developed a new class of drug compounds that reduce harmful inflammation while leaving the body's ability to fight infections intact-a long-sought goal in treating autoimmune diseases.
 
   FDA clears investigational new drug application to test sCAR-T therapy for autoimmune conditionsFDA clears investigational new drug application to test sCAR-T therapy for autoimmune conditions
 
Calibr-Skaggs Institute for Innovative Medicines, the drug discovery division of Scripps Research, announced today that the FDA has cleared their investigational new drug (IND) application to study switchable chimeric antigen receptor T cell (sCAR-T) therapy (CLBR001 + SWI019) in patients with autoimmune conditions.
 
   Duloxetine fails to prevent nerve damage caused by chemotherapyDuloxetine fails to prevent nerve damage caused by chemotherapy
 
A randomized trial conducted by the Alliance for Clinical Trials in Oncology with support from the National Cancer Institute has found that duloxetine, a medication commonly used to treat chronic pain and psychiatric conditions, does not prevent nerve damage caused by chemotherapy in patients with colorectal cancer.
 
   Natural peptide PEPITEM shows promise in reducing arthritic joint swellingNatural peptide PEPITEM shows promise in reducing arthritic joint swelling
 
Scientists investigating the naturally occurring immunopeptide PEPITEM have shown reductions in arthritic joint swelling to a degree comparable to the current standard of care, and reduce the inflammatory changes that cause joint damage.
 
 Researchers identify molecular link between autoimmune disease and lymphoma risk
 
Researchers identify molecular link between autoimmune disease and lymphoma riskPatients with autoimmune diseases such as lupus and rheumatoid arthritis have an increased risk of developing lymphoma, a form of blood cancer that affects the lymphatic system.
 
 
 Novel ENDOtollins block harmful inflammation while preserving infection response
 
Novel ENDOtollins block harmful inflammation while preserving infection responseScripps Research scientists have developed a new class of drug compounds that reduce harmful inflammation while leaving the body's ability to fight infections intact-a long-sought goal in treating autoimmune diseases.
 
 
 Extracellular vesicles from menstrual blood cells show potential to stimulate cartilage repair
 
New research by an interdisciplinary team in Lithuania has revealed a promising and unconventional approach to cartilage regeneration.
 
 
 Study identifies four radiomic profiles linked to sarcoidosis severity
 
Researchers have identified a new method for analyzing chest CT scans that may help physicians better understand the different forms of sarcoidosis, a complex inflammatory lung disease that affects more than 150,000 people in the United States.
 
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