AI system predicts future knee X-rays to transform osteoarthritis care
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 Aerobic exercise found to be most effective for knee osteoarthritisAerobic exercise found to be most effective for knee osteoarthritis
 
For patients with knee osteoarthritis, aerobic activities such as walking, cycling, or swimming are likely to be the best exercise for improving pain, function, gait performance, and quality of life, finds a study published by The BMJ today.
 
 
 AI system predicts future knee X-rays to transform osteoarthritis careAI system predicts future knee X-rays to transform osteoarthritis care
 
An AI system that can predict what a patient's knee X-ray will look like a year in the future could transform how millions of people with osteoarthritis understand and manage their condition, according to research by the University of Surrey.
 
   SGLT-2 inhibitors offer protection against autoimmune conditionsSGLT-2 inhibitors offer protection against autoimmune conditions
 
Sodium-glucose cotransporter-2 (SGLT-2) inhibitors used to treat type 2 diabetes are associated with an 11% lower risk of autoimmune rheumatic diseases, such as rheumatoid arthritis and lupus, compared with another group of diabetes drugs called sulfonylureas, finds a study from South Korea published by The BMJ today.
 
   Football injuries, not injections, explain why retired players face higher osteoarthritis riskFootball injuries, not injections, explain why retired players face higher osteoarthritis risk
 
Retired UK male footballers face a markedly higher risk of foot and ankle osteoarthritis (OA), primarily due to prior injuries sustained during their careers. While corticosteroid injections were linked with OA, this association likely reflects treatment for injury rather than a direct cause.
 
   Foot or ankle injuries in professional football players may increase risk of osteoarthritisFoot or ankle injuries in professional football players may increase risk of osteoarthritis
 
A new paper in Rheumatology, published by Oxford University Press, finds that retired UK male professional football players who reported foot or ankle injuries during their careers were more likely to develop osteoarthritis in retirement.
 
 Rozanolixizumab prevents congenital heart block in high-risk pregnancy
 
Rozanolixizumab prevents congenital heart block in high-risk pregnancyCongenital heart block, sometimes referred to as cardiac neonatal lupus, is a rare but potentially life-threatening condition that affects babies born to mothers with specific autoantibodies - called anti-SSA/Ro antibodies - which can attack the fetal heart via its electrical conduction system, leading to a slower heart rate.
 
 
 New study reveals how the glucocorticoid receptor forms complex structures inside cells
 
Drugs to treat inflammatory and autoimmune diseases - such as asthma, psoriasis, rheumatoid arthritis or Chrousos syndrome - act mainly through the glucocorticoid receptor (GR).
 
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