In a first-of-its-kind genome-wide association study (GWAS) researchers have discovered two genes, RNF144B and ENPP1, that cause calcium pyrophosphate deposition (CPPD) disease in Americans of European and African descent.
This comprehensive GWAS reveals 15 new genetic variants linked to celiac disease, offering insights for earlier detection and tailored treatment strategies.
In a significant advancement for hand rehabilitation, researchers from Zhengzhou University have introduced a non-hand-worn, load-free VR hand rehabilitation system that could boost therapy development for patients recovering from conditions like stroke and osteoarthritis.
Herpes zoster (HZ) is common in older people, with a lifetime risk of 25%. The main risk factors are advanced age and immunosuppression. People with a rheumatic and musculoskeletal disease have an overall higher risk for shingles.
Is there a benefit to early bDMARD? In psoriatic arthritis (PsA) EULAR - The European Alliance of Associations for Rheumatology - recommends a treat-to-target approach, and suggests more intensive therapy for people with poor prognostic factors, depending on the disease presentation.
Conventional transcriptomic techniques have revealed much about gene expression at the population and single-cell level—but they overlook one crucial factor: spatial context.
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