Inflammatory messenger substance interferon-alpha can trigger Sjögren's syndrome
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 Exercise may provide limited relief for hip osteoarthritis symptomsExercise may provide limited relief for hip osteoarthritis symptoms
 
Exercise finds improvements in pain and function may fall short of what patients would notice in daily life, but more studies are needed to make firm conclusions, a new Cochrane review finds.
 
 
 Inflammatory messenger substance interferon-alpha can trigger Sjögren's syndromeInflammatory messenger substance interferon-alpha can trigger Sjögren's syndrome
 
Findings from Bonn, Edinburgh and Newcastle could give a boost to pharmaceutical research.
 
   Dysregulation of immune regulator NF-κB drives major human diseasesDysregulation of immune regulator NF-κB drives major human diseases
 
NF‑κB controls genes involved in inflammation, immunity, cell survival, and proliferation. Triggered by cytokines (TNF‑α, IL‑1β), microbial products, or cellular stress, it translocates to the nucleus and induces pro‑inflammatory mediators.
 
   Repeatedly losing and gaining weight may accelerate muscle lossRepeatedly losing and gaining weight may accelerate muscle loss
 
Repeatedly losing and gaining weight may do more than frustrate dieters - it also accelerates muscle loss in middle-aged people, according to new UC San Francisco research that comes as weight-loss medications transform obesity treatment.
 
   Oral microbiome imbalances may contribute to symptomatic hand arthritisOral microbiome imbalances may contribute to symptomatic hand arthritis
 
Specific imbalances and disruptions to the oral microbiome have been linked to symptomatic hand arthritis by a study published online in the open access journal RMD Open.
 
 The role of TNFSF trimers in next-generation therapeutics
 
The role of TNFSF trimers in next-generation therapeuticsNative-like TNFSF trimers are helping researchers develop more physiologically relevant tools for therapeutic discovery and development.
 
 
 New clinical framework maps pediatric Behçet’s spectrum disorders
 
New clinical framework maps pediatric Behçet’s spectrum disordersBehçet's disease (BD) is a systemic vasculitis marked by recurrent oral and genital ulcers, but pediatric presentations are often partial or atypical, complicating diagnosis.
 
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