Pharmacy / Pharmacology - Pharmacokinetics of Cannabis and its Secondary Metabolites
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  September 13, 2019  
  Pharmacy / Pharmacology  
  The latest pharmacy / pharmacology news from News Medical  
 

#ALT# Video: When HPLC fails: Unleashing the Potential of Ion Chromatography

The scope of HPLC is very limited for analyses of sugars in water and various foods. For such food and beverage analyses, ion chromatography (IC) is the better solution. Why? IC can separate multiple ions and detect them using a conductivity detector. And because chemical suppression lowers background conductivity, sensitivity is not an issue, making IC suitable for trace- and ultratrace-level measurements.

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   New leukemia treatment developed from common wild flowerNew leukemia treatment developed from common wild flower
 
Researchers at Birmingham University have discovered how to turn a compound from a common wildflower called Feverfew into a new treatment for cancer. The team found a way to extract the naturally-occurring substance, called parthenolide, from the plant’s leaves and modify it so that it could destroy chronic lymphocytic leukemia (CLL) cells.
 
   Pharmacokinetics of Cannabis and its Secondary MetabolitesPharmacokinetics of Cannabis and its Secondary Metabolites
 
Once Cannabis enters the body, it undergoes a variety of different biological pathways that allow for its therapeutic effects to arise. In order to gain a better understanding as to how Cannabis can be efficiently used for medicinal purposes, it is imperative to investigate its pharmacokinetic properties following consumption.
 
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 NIH trial aims to improve drug discovery for ischemic stroke
 
NIH trial aims to improve drug discovery for ischemic strokeThe National Institutes of Health (NIH) has announced it will fund a nationwide preclinical trial platform called the Stroke Preclinical Assessment Network (SPAN) to ensure candidate new treatments for acute ischemic stroke are tested systematically and efficiently in rodents.
 
 
 MRI scans show how ADHD medication affects brain structure in children
 
MRI scans show how ADHD medication affects brain structure in childrenAttention deficit/hyperactivity disorder (ADHD) affects an increasing number of people worldwide, with an estimated 6.1 million children were living with ADHD in 2016, according to the National Survey of Children’s Health. Now, MRI scans have revealed that children taking the common medication methylphenidate experience alterations in the distribution of white matter in the brain.
 
 
 Exploring the Structure-Activity Relationship (SAR) of Drugs
 
Exploring the Structure-Activity Relationship (SAR) of DrugsThe structure-activity relationship (SAR) aids in understanding various aspects of drug discovery, from screening drug candidates to optimizing their properties. The effective biological activity is contributed by the various geometric and electrostatic interactions.