Big breakfast study reveals protein curbs appetite but fiber delivers stronger gut microbiome benefits
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 Ozempic users continue treatment when weight loss works despite side effectsOzempic users continue treatment when weight loss works despite side effects
 
A study on Ozempic for weight loss reveals user satisfaction is driven by efficacy, despite common gastrointestinal side effects impacting treatment adherence.
 
 
 Big breakfast study reveals protein curbs appetite but fiber delivers stronger gut microbiome benefitsBig breakfast study reveals protein curbs appetite but fiber delivers stronger gut microbiome benefits
 
A randomized crossover weight loss trial in adults with overweight or obesity found that higher protein big breakfasts improved satiety, while higher fibre breakfasts produced slightly greater weight loss and more favourable gut microbiota markers. Both diets improved metabolic biomarkers, but microbiota changes reflected surrogate gut health indicators rather than direct clinical outcomes.
 
   Distinct microbial signature identified in pediatric Crohn's diseaseDistinct microbial signature identified in pediatric Crohn's disease
 
NYU researchers have found a "microbial signature" of pediatric Crohn's disease that differs from the makeup of gut bacteria in children with other gastrointestinal conditions, with Crohn's patients harboring more pro-inflammatory bacteria and less protective bacteria.
 
   Global study reveals disparities in early-onset gastric cancerGlobal study reveals disparities in early-onset gastric cancer
 
Gastric cancer remains the fifth leading cause of cancer-related deaths worldwide. Although its overall incidence has declined, early-onset cases—diagnosed before age 50—display unique biological and clinical patterns.
 
   Engineered Listeria boosts innate immunity against cancerEngineered Listeria boosts innate immunity against cancer
 
After nearly 40 years of research on how Listeria bacteria manipulate our cells and battle our immune system to cause listeriosis, Daniel Portnoy and his colleagues have discovered a way to turn the bacteria into a potent booster of the immune system - and a potential weapon against cancer.
 
 Dysplasia grade predicts colorectal cancer risk in people with IBD
 
Dysplasia grade predicts colorectal cancer risk in people with IBDPeople with inflammatory bowel disease (IBD) and precancerous colorectal lesions are much more likely to develop colorectal cancer, a new study shows.
 
 
 HER2 gastric cancer: Unraveling resistance at single-cell resolution
 
HER2 gastric cancer: Unraveling resistance at single-cell resolutionHER2-positive gastric cancer accounts for a substantial proportion of advanced cases and has long been treated with HER2-targeted therapies.
 
 
 Developmental ANGPTL4 deficiency protects mice from colitis and tumors
 
Developmental ANGPTL4 deficiency protects mice from colitis and tumorsA novel study using a mouse model has found that the absence of the angiopoietin-like 4 (ANGPTL4) protein during development triggers a long-lasting reprogramming of the immune system that protects against intestinal inflammation.
 
 
 Human 3D model shows how the gut drives neurodegeneration
 
Human 3D model shows how the gut drives neurodegenerationResearch on a 3D microfluidic model highlights gut-brain interactions, offering new insights into inflammatory processes linked to neurodegenerative diseases.
 
 
 Cornell study finds existing drug could boost liver cancer immunotherapy
 
Immunotherapy – which activates the body's own immune system to kill cancer cells – has not worked well against a rare and fatal liver cancer, but a new Cornell University study finds an existing FDA-approved drug may allow the immunotherapy to fight the cancer as intended, opening the door to a potential treatment.
 
 
 Axol Bioscience acquires ophthalmology business from Newcells Biotech
 
Axol Bioscience Ltd. (Axol), a leading provider of induced pluripotent stem cell (iPSC) technologies for drug discovery and research, today announced that it has acquired the ophthalmology business of Newcells Biotech (Newcells), a leading drug discovery partner specializing in the development of in vitro models and bespoke assay services.
 
 
 AI tool can accurately predict colorectal cancer risk in UC-LGD patients
 
People with ulcerative colitis (UC), a chronic inflammatory bowel disease, are up to four times more likely to develop colorectal cancer than the general population.
 
 
 Advances in pathogenesis and management of gastrointestinal motility disorders
 
Announcing a new publication for Acta Materia Medica journal. Gastrointestinal motility disorders (GIMDs) are characterized by impaired gastrointestinal motility.
 
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