Scientists show gut bacteria can reach the brain in mice and reveal a potential vagus nerve pathway

	Gastroenterology
	The latest gastroenterology‎ news from News Medical

	Scientists show gut bacteria can reach the brain in mice and reveal a potential vagus nerve pathway Researchers found that very small numbers of gut bacteria can translocate to the brain in mice, particularly when gut barrier permeability increases due to a Paigen diet. Evidence suggests the vagus nerve may serve as a partial route for this gut-to-brain microbial movement.

	Why do some people respond better to GLP-1 drugs? Gut microbiome may hold clues A review in the Canadian Journal of Physiology and Pharmacology examines emerging evidence linking glucagon-like peptide-1 receptor agonists (GLP-1 RAs), the gut microbiome, and obesity treatment outcomes. The authors conclude that microbiome changes seen during therapy are most likely driven by diet, behavior, and weight loss, although microbial profiling may eventually help predict patient responses.

			How one antibiotic dose can reshape your gut microbiome for years Long-term registry-linked analysis of nearly 15,000 adults shows that antibiotic use is associated with persistent changes in gut microbiome diversity and composition for up to 4–8 years. These effects vary by antibiotic class, with clindamycin, fluoroquinolones, and flucloxacillin showing the strongest and most sustained associations.

			Researchers identify cellular drivers of gut scarring in Crohn’s disease As inflamed regions of the gut form scar tissue, the space within the gut lumen becomes smaller and more restricted, leading to symptoms of gut obstruction.

			New microbiome therapy improves autism symptoms in children This study evaluates a new fecal microbiota transplant method, revealing significant symptom improvements in children with autism without invasive procedures.

	Childhood stress may lead to digestive issues later in life Early life stress may lead to digestive issues later in life, driven by changes in the gut and sympathetic nervous systems, according to a new study published in the journal Gastroenterology.

	How GLP-1 weight-loss drugs affect appetite, mood, and behavior In addition to their weight loss benefits, GLP-1 RAs also act on neural circuits involved in appetite, impulse control, and reward.

	Can Ashwagandha gummies help kids focus better? A study shows Ashwagandha gummies may enhance cognitive performance and sleep quality in children, offering a safe herbal approach to support development.

	Certain antibiotics leave lasting footprints on human gut microbiome Antibiotic treatments can affect the composition of the community of bacteria living in the gut, known as the gut microbiome, for a long time.

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