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The latest gastroenterology news from News Medical |
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 | | |  Do spicy foods help or hurt your gut health? Capsaicin, the spicy compound in chili peppers, not only influences inflammation, metabolism, and cancer risk but also shapes the gut microbiome in complex, context-dependent ways. This comprehensive review highlights both the therapeutic promise and potential risks of capsaicin, calling for deeper research into its microbiome-mediated effects. | | | | |  Gut microbe emerges as a promising tool in the fight against COVID-19 Researchers found that Akkermansia muciniphila boosts lung-specific antiviral immunity against SARS-CoV-2 in mice by modulating the gut–lung axis. This commensal gut bacterium shows promise as a potential biomarker and biotherapeutic candidate for COVID-19 and other respiratory infections. | |
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| | | | |  Once-weekly amycretin, a novel peptide activating GLP-1, amylin, and calcitonin receptors, produced rapid, substantial, and sustained weight loss in adults with overweight or obesity during a phase 1b/2a trial. The treatment was generally well tolerated, with mostly mild to moderate gastrointestinal side effects, supporting further investigation in larger, longer studies. | | | | |  A 68-week phase 3 trial found that coadministered cagrilintide and semaglutide led to significant and clinically meaningful weight loss in adults with obesity but no diabetes. The combination outperformed either drug alone and improved multiple cardiometabolic health markers. | | | | |  Lower blood sugar and increased fat burning – without negatively affecting appetite or muscle mass. These are some of the most promising effects of a new potential drug treatment for people with type 2 diabetes and obesity, according to a new study published in the journal Cell by researchers from Karolinska Institutet and Stockholm University. | | | | |  Living with an autoimmune disease is linked to a near doubling in the risk of persistent mental health issues, such as depression, generalised anxiety, and bipolar disorder, with these risks higher in women than in men, finds a large population-based UK study, published in the open access journal BMJ Mental Health. | | | | |  A low FODMAP diet developed by Monash University researchers for irritable bowel syndrome (IBS) has been shown to improve gastrointestinal symptoms in women with endometriosis. | | | | |  Recent evidence suggests methylene blue may help reduce vasopressor needs and ICU stays in septic shock, but current data do not support replacing standard therapies. Further research is needed to clarify its optimal dosing, timing, and patient selection for best outcomes. | | | | |  Weight loss surgery has long been an effective treatment for the more than 40 percent of American adults struggling with obesity. | | | | |  Esophageal adenocarcinoma (EAC), one of two major forms of esophageal cancer, is the sixth most deadly cancer worldwide for which no effective targeted therapy exists. | | | | |  Antibiotics are one of the greatest triumphs in the history of medical science - but these lifesaving tools have a dark side. | | | | |  Stephanie Ivory counts on Medicaid to get treated for gastrointestinal conditions and a bulging disc that makes standing or sitting for long periods painful. Her disabilities keep her from working, she said. | | | | |  Appendix cancer is a rare but increasingly recognized malignancy, often discovered incidentally during surgery for presumed appendicitis. Advances in imaging, molecular profiling, and classification have improved diagnosis, management, and spurred ongoing research into targeted therapies. | | | | |  Discover how genetics and diet shape the human gut microbiome, influencing health, metabolism, and disease risk. Explore implications for precision nutrition. | |
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