How could bisphenol A raise depression risk? Study identifies six key molecular targets
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 Loving-kindness meditation links to lower anxiety through self-compassionLoving-kindness meditation links to lower anxiety through self-compassion
 
A new study suggests that loving-kindness and compassion meditation may be linked to lower anxiety over time, not just through longer practice, but also by building self-compassion and loosening the grip of distressing thoughts.
 
 
 How could bisphenol A raise depression risk? Study identifies six key molecular targetsHow could bisphenol A raise depression risk? Study identifies six key molecular targets
 
An integrative Translational Psychiatry study linked BPA exposure to major depressive disorder by identifying 571 shared targets and six core genes, with genetic, transcriptomic, docking, and mouse-model data supporting plausible mechanistic pathways. The strongest signals pointed to AKT1, SRC, PLCG2, and JAK3 as potential contributors, while EGFR appeared protective.
 
   Highly potent opioid shows potential as therapy for pain and opioid use disorderHighly potent opioid shows potential as therapy for pain and opioid use disorder
 
Researchers at the National Institutes of Health (NIH) have identified a novel, highly potent opioid that shows potential as a therapy for both pain and opioid use disorder.
 
   Smartphone app HabitWorks improves anxiety and depression symptomsSmartphone app HabitWorks improves anxiety and depression symptoms
 
In an effort to increase access to evidence-based interventions to help manage anxiety and depression, Mass General Brigham investigators have developed and tested a novel digital intervention called HabitWorks.
 
   New clinical guideline adopts holistic approach to brain and heart healthNew clinical guideline adopts holistic approach to brain and heart health
 
A new brain–heart clinical practice guideline takes a holistic approach, integrating neurologic and mental health evidence with guidance for cardiovascular disease as many brain and heart conditions overlap and share similar risk factors.
 
 Testosterone level is not always the key to male wellbeing
 
Testosterone level is not always the key to male wellbeingThe connection between testosterone and well-being is weaker than many people think. Although there are clear health connections, a higher testosterone level is not always the key to well-being, according to a thesis at the University of Gothenburg.
 
 
 Children’s screen use surged significantly during and after pandemic
 
Children’s screen use surged significantly during and after pandemicFirst systematic review to track long-term trends across pre- and post-pandemic periods finds dramatic rise in screen use among children and adolescents.
 
 
 Identity cohesion linked to better mental health in marginalized groups
 
Identity cohesion linked to better mental health in marginalized groupsPeople of color who are also part of sexual and gender minority groups face unique challenges shaped by overlapping forms of discrimination. While much research has focused on the mental health risks they experience, far less has explored how people of these multiple identities build strength and resilience.
 
 
 Antibiotic use before and during pregnancy linked to psychological distress
 
Antibiotic use before and during pregnancy linked to psychological distressPerinatal depression, which occurs during pregnancy or in the period after childbirth, is one of the most common mental health conditions experienced by women.
 
 
 Polygenic embryo testing raises ethical concerns beyond disease prevention
 
Polygenic embryo testing raises ethical concerns beyond disease preventionFor more than four decades, in vitro fertilization (IVF) has helped families have children. Scientists estimate that more than 10 million people worldwide have been born through IVF and related assisted reproductive technologies, according to the International Committee for Monitoring Assisted Reproductive Technologies.
 
 
 NOX-1 identified as key molecular target to prolong ketamine's antidepressant effects
 
NOX-1 identified as key molecular target to prolong ketamine's antidepressant effectsTreatment-resistant depression affects a large proportion of people with major depressive disorder, and while ketamine offers rapid relief, its antidepressant effects fade within a few weeks.
 
 
 Largest bipolar disorder dataset launched to advance personalized care
 
Largest bipolar disorder dataset launched to advance personalized careBD²: Breakthrough Discoveries for thriving with Bipolar Disorder today announced the first public release of data from the BD² Integrated Network Longitudinal Cohort Study (LCS).
 
 
 Finnish study reveals how parental immigration status impacts child mental health
 
Finnish study reveals how parental immigration status impacts child mental healthA new nationwide Finnish register study shows that children with two immigrant parents are significantly less likely to receive mental health services for anxiety and depression than children of Finnish parents.
 
 
 Losing a parent hits harder with fewer siblings
 
Losing a parent hits harder with fewer siblingsFindings suggest that having siblings may buffer the mental health impact of parental loss, with fewer siblings associated with increased medication use.
 
 
 New brain circuit discovery offers hope for chronic pain treatment
 
New brain circuit discovery offers hope for chronic pain treatmentA new map of a brain circuit specific to chronic pain suggests a promising route to treatment for the roughly 60 million Americans living with persistent pain, according to a study published in Nature.
 
 
 Trial tests fast-acting brain stimulation for postpartum depression treatment
 
Trial tests fast-acting brain stimulation for postpartum depression treatmentThe Icahn School of Medicine at Mount Sinai today announced the enrollment of its first patient in a U.S. Department of Defense-funded pivotal clinical trial to evaluate whether a fast-acting, drug-free brain stimulation therapy can safely and quickly relieve symptoms of postpartum depression.
 
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