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The latest cell & molecular biology news from News Medical |
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 Accelerating cell and gene therapy application testing
Celleo Biotech is using the PIPETBOY GENIUS serological pipet controller to perform various cell culture tasks. The PIPETBOY GENIUS, combined with INTEGRA’s serological pipets, has streamlined the lab’s workflow with its set volumetric control, enabling effortless, time-saving and consistent dispensing at the click of a button. This feature, as well as precise and efficient liquid handling, supports Celleo in testing and validating a variety of novel cell and gene therapy applications.
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| | | | |  CERTOMICS is a Nextflow-based computational pipeline designed to identify and profile CAR-engineered immune cells using single-cell multiomics data. By integrating gene expression, immune receptor profiling, protein markers, CAR-aware references, and CAR-specific quality control, it supports more standardized analysis of adoptive cellular immunotherapies. | | | | |  This in vitro study found that negatively charged SiO2 nanoparticles suppressed antigen-induced degranulation and activation-marker changes in IgE-sensitized mouse bone marrow-derived mast cells. By contrast, mTiO2 nanoparticles showed cytotoxic and pro-inflammatory effects, including enhanced DNP-induced IL-6 release, suggesting nanoparticle composition can shape early allergic immune responses. | | | | |  Teemu Miettinen discusses his innovative method for measuring intracellular water, revealing its critical role in cell function and disease mechanisms. | | | | |  A new study shows that how a cell fails to divide after copying its DNA can determine its fate. | | | | |  A largely overlooked structure inside our cells may play a crucial role in how the brain forms, offering new insight into developmental disorders and potential therapies. | |
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