Cell Line Authentication using DNA Barcoding

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	May 13, 2019
	Cell Biology
	The latest cell & molecular biology news from News Medical

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Oxford Genetics, a leader in synthetic biology, is a specialised contract research organisation offering services to support the discovery, development and production of biologics, with a particular focus on viral vectors for gene therapy applications. A unifying theme across the portfolio is expertise in DNA design, expression system optimisation, cell line development and engineering of viral delivery systems. We are located within purpose-fitted laboratories at the Oxford Science Park, just South of Oxford.

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			Cell Line Authentication using DNA Barcoding DNA barcoding - the identification of a specific cell line using a genetic sequence - is a solution that has been proposed to solve the issue of cell line contamination.

			Cell‐Cycle‐Dependent Regulation of Cell Adhesions This article will describe recent studies which have expanded our knowledge of the role of focal adhesions in the cell cycle.

	Autophagy of dendritic cells supports T-cell anticancer activity Autophagy contributes to the homeostasis of a cell and recently another function of autophagy has been reported. A KAIST research team found that the autophagy of dendritic cells supports T-cell anticancer activity.

	Scientists successfully create melanocyte precursor cells using stem cell technology Our hair, skin and eyes are colored by a pigment called melanin, which is produced by pigment cells called melanocytes. Scientists have used stem cell technology to successfully create melanocyte precursor cells.

	Human Cell Line Authentication by STR Profiling Short Tandem Repeat (STR) DNA profiling is one solution that has been proposed for the detection of cross-contamination and therefore authentication of human cell lines.

	Potential stem cell therapies moving from lab bench to clinical application Stem cell research is leading to potential new therapies to treat disease, with several applications in clinical trials or expected to enter trials in the coming months.

	Study compares single cell and MSC micropellets for cartilage regeneration Repair of cartilage injuries or defects is aided by the introduction of mesenchymal stem cells (MSCs), which can be incorporated into hydrogels to amplify their effects.

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