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The latest cell & molecular biology news from News Medical |
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 3D Imaging Advances Study of Glomerular Diseases
Researchers at Juntendo University have used FIB-SEM imaging and Amira Software to create detailed 3D models of glomerular endothelial cells (GEnCs) in adult rats. This innovative approach reveals both luminal and basal surface structures, enhancing understanding of glomerular diseases. These findings benefit nephrologists, pathologists, and biomedical researchers by improving structural analysis and pathologic evaluation of GEnCs in kidney diseases.
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| | |  Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the immune system. | | | | |  Researchers found that microplastics from everyday plastic tableware accumulate in human semen and, although not linked to semen quality in the full cohort, were associated with altered sperm parameters in specific subgroups. Experimental models confirmed that 50 nm polystyrene particles trigger autophagy and apoptosis via the FOXA1/MAP3K1/p38 pathway, impairing sperm structure and function. | | | | |  Nuclear pore complexes (NPCs) are tiny but sophisticated gatekeepers that control the flow of materials between a cell's nucleus and its cytoplasm by quickly selecting which molecules to transport across the nuclear membrane. | |
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