Microbiology - Moving Over to Digital Pathology
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#ALT# Investigating Dermatophyte Colonization with Lab Grown Skin

This study sought to develop methods to evaluate anti-dermatophyte treatments by using reproducible invasion in lab grown skin.

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    KeysightMoving Over to Digital Pathology
 
It can be a long and complex process to sell and buy a slide scanner. Digital pathology is often seen an expensive and workflow-problematic future tech. Hard work has been carried out by medical equipment suppliers to break this entry barrier for going digital. Now, new, highly compatible technology is available that makes business sense for both parties.
 
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   Scientists modify a toxic protein to create a biosensorScientists modify a toxic protein to create a biosensor
 
Some types of bacteria kill other cells by releasing proteins called “pore-forming toxins” (PFTs) that create holes in the cell membrane. The PFTs bind to the cell membrane and burrow into, creating a tube-like channel or pore. Once enough holes have been punched into the cell membrane by these toxins, the target cell destroys itself.
 
 Does the Microbiome Affect Immunotherapy Outcomes?
 
Does the Microbiome Affect Immunotherapy Outcomes?The microbiome consists of about 100 trillion microbes (microbiota) and their genomes. These are made of bacteriophage, fungi, bacteria, protozoa (single-cell eukaryotes), and viruses in the human body. They play an important role in health maintenance systems of the immune system, as well as in drugs and foreign substances (xenobiotics) metabolism.
 
 
 British Pioneers in Microbiology
 
British Pioneers in MicrobiologyHumans have been studying microorganisms for hundreds of years. The first compound microscope was invented by the Janssen brothers (Johannes and Zacharias) in 1590, and formed the basis for the many discoveries that followed. From the 16th century onward, many theories were framed as to the way microbes flourished and spread. Contact between infected individuals was proposed in 1546 or earlier.
 
 
 Ultraviolet B light is good for the gut microbiome
 
Ultraviolet B light is good for the gut microbiomeA small study published in the journal Frontiers in Immunologyon October 24, 2019, shows that exposure to ultraviolet B (UVB) light, which is commonly achieved through sunlight exposure, can trigger specific beneficial changes in the gut microbiome, which are dependent on the preceding serum levels of vitamin D.
 
 
 Using Phage Display for Antibody Discovery and Development
 
Using Phage Display for Antibody Discovery and DevelopmentIn phage-display, a gene encoding the surface protein of a bacteriophage is replaced with a gene encoding a novel protein. The technique can be used in drug discovery and research for the investigation of novel polypeptides.