Biochemistry - Unlock Drug Discovery with Binding Kinetics Insights
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Polymer–DNA Nanoparticle Studies with ATR-FTIRPolymer–DNA Nanoparticle Studies with ATR-FTIR

This application note demonstrates how ATR-FTIR spectroscopy can characterize polyethyleneimide (PEI)–DNA nanoparticle complexes for gene and drug delivery. By revealing key molecular interactions, ATR-FTIR supports optimization of stability, efficiency, and safety, offering insights that advance the development of more effective therapeutic delivery systems.

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    Unlock Drug Discovery with Binding Kinetics InsightsUnlock Drug Discovery with Binding Kinetics Insights
 
Accurate drug–target binding data is vital for predicting in vivo efficacy and avoiding costly late-stage failures. This eBook explores cutting-edge methods and technologies for kinetic analysis, offering strategies to integrate binding kinetics earlier in the drug discovery workflow. Download now to enhance precision and accelerate research success.
 
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   Nanomaterials in Skincare: Advances, Efficacy, and Safety ConcernsNanomaterials in Skincare: Advances, Efficacy, and Safety Concerns
 
Innovative nanomaterials in skincare improve cosmetic formulations, offering targeted delivery and enhanced stability for effective dermatological applications.
 
 Gene expression maps explain why diseases often occur together
 
Gene expression maps explain why diseases often occur togetherThis study reveals how gene expression patterns uncover molecular pathways linking comorbidities, enhancing treatment strategies for overlapping diseases.
 
 
 Organ Development Shaped Equally by Mechanics and Biochemistry
 
Organ Development Shaped Equally by Mechanics and BiochemistryA new study looks at the physical forces that help shape developing organs. Scientists in the past believed that the fast-acting biochemistry of genes and proteins is responsible for directing this choreography.
 
 
 Reengineered enzyme enables precise detection of cell surface glycans
 
Reengineered enzyme enables precise detection of cell surface glycansSugars known as glycans form dense envelopes around cells. But they're often ignored in biological investigations because, unlike DNA, proteins and other cellular components, tools to study them are lacking.
 
 
 Sex and residual enzyme activity primarily determine clinical course in Chinese Fabry patients
 
Sex and residual enzyme activity primarily determine clinical course in Chinese Fabry patientsFabry disease in mainland China is now mapped through the largest single-centre cohort to date, clarifying how α-galactosidase A deficiency, genotype and sex jointly sculpt the clinical spectrum.
 
 
 Polβ enzyme found to protect developing brain from harmful DNA mutations
 
Polβ enzyme found to protect developing brain from harmful DNA mutationsA research group led by The University of Osaka has discovered that the DNA repair enzyme Polβ plays a crucial role in protecting the developing brain from harmful mutations.
 
 

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