| The latest biochemistry news from AZoNetwork |
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The latest biochemistry news from AZoNetwork |
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 | | |  The Use of IMC-MS for Protein Characterization
In the pharmaceutical industry, accurate characterization of protein structure is crucial to understanding protein function and in facilitating the design of effective therapeutics. IMS separates ions based on their differential mobility through a drift-tube containing buffer gas. The differing mobility depends on an ion’s characteristic collision cross-section (CSS), which is greater in the case of larger ions that experience more collisions and take longer to cross the drift tube than smaller ions. Learn More at Pittcon 2020 in Chicago.
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| | | | |  While healthcare has made significant advancements over the last century, and medical professionals are more equipped than ever with the tools to treat a whole range of illnesses, the landscape of healthcare continues to evolve, and with this ever-changing environment comes the continued need for new drug candidates. | | | | |  A team from the Universidade da Beira, Portugal have developed a rapid and non-expensive analytical method for characterising minicircle DNA (mcDNA). This methodology represents the first analytical chromatographic method for the quantification of mcDNA. This work builds on existing research from which a purification strategy for the isolation of supercoiled (sc) mcDNA is achieved using a cadaverine-modified monolith. | | | | |  Polyethylene glycol (PEG) is a biocompatible, synthetic, hydrophilic polyether compound that has many applications, mostly in the medical industry, but also in the chemical and industrial sectors. The structure of the compound is known as H−(O−CH2−CH2)n−OH. | |
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