The Blended Genome Exome: Leveraging the Lunatic for High Scale Genomic Sequencing

	Genomics
	The latest genomics news from News Medical

[Free Webinar] The Blended Genome Exome: Leveraging the Lunatic for High Scale Genomic Sequencing

Broad Clinical Labs developed the blended genome exome (BGE) method, a high-throughput DNA library construction assay that produces low-pass whole-genome (1–4× mean depth) and deep whole-exome (30–40× mean depth) data in a single sequencing run. The BGE process relies on several automation instruments to ensure quality control of this process at scale, including the Lunatic UV/Vis spectrophotometer from Unchained Labs.

In this webinar, Unchained Labs will explore the BGE product through the lab workflow and highlight the implementation of the Lunatic for reliable, scalable quality control.

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			Genomics and AI identify a candidate gene behind rare neurodevelopmental disorder Researchers at Baylor College of Medicine, the Duncan Neurological Research Institute (Duncan NRI) at Texas Children's Hospital, the Texome Project and collaborating institutions have identified variants in gene BRSK1 as a likely diagnosis for individuals with a rare and complex neurodevelopmental disorder who until now had not received an explanation for their condition.

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	Cancer cells erase sections of Y chromosome to trigger tumor growth in men A new study found that cancer cells selectively chip away gene-rich sections of the Y chromosome, triggering ripples that regulate tumor growth.

	Y chromosome loss creates hidden cancer vulnerability in men A study initiated by a University of Arizona Cancer Center physician-scientist Dr. Dan Theodorescu revealed that the loss of the Y chromosome in men's body tissue could pave the way for cancer to develop in that tissue.

	CRISPR activation library uncovers gene driving lymphoma growth and resistance Researchers have uncovered a previously unknown gene causing resistance to a leading blood cancer drug and several genes that accelerate lymphoma growth by using a powerful new CRISPR activation library.

	Researchers Simulate Microgravity to Isolate Gravity's Impact on Human Chromatin The Human Genome Project was launched in 1990, preceded by decades of breakthroughs in genetics. It eventually gave us a sequence of the human genome.

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