Request a Sample: Research Transfection Reagents

	Genomics
	The latest genomics news from News Medical

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High-performing NGS library prep with enzymatic DNA fragmentation is possible

Historically, DNA library prep kits with enzymatic fragmentation have been plagued by higher levels of sequencing artifacts compared to kits that use mechanically fragmented DNA. A new enzymatic fragmentation formula has solved that problem—while reducing hands-on-time and pipetting steps.

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Research reveals inaccuracies in common gene therapy measurement technique

In a finding with implications for one of the most promising cutting-edge medical treatments, researchers evaluated several measurement techniques commonly used in gene therapy.

	New gene-editing treatment extends lifespan in mice with prion disease Researchers at the Broad Institute of MIT and Harvard have developed a gene-editing treatment for prion disease that extends lifespan by about 50 percent in a mouse model of the fatal neurodegenerative condition.

	Bidirectional movement drives DNA loop formation Scientists from Delft, Vienna, and Lausanne discovered that the protein machines that shape our DNA can switch direction. Until now, researchers believed that these so-called SMC motors that make loops into DNA could move in one direction only. The discovery, which is published in Cell, is key to understanding how these motors shape our genome and regulate our genes.

	Symbiosis and horizontal gene transfer shape leaf beetle evolution With more than 50,000 described species, the leaf beetle family is distributed worldwide and represents about a quarter of the species diversity of all herbivores.

	Breakthrough reveals how DNA and RNA epigenetics work together to control genes Our genes contain all the instructions our body needs to function, but their expression must be finely regulated to guarantee that each cell performs its role optimally.

	Ancient viral DNA plays crucial role in early embryo development Over half of our genomes consists of thousands of remnants of ancient viral DNA, known as transposable elements, which are widespread across the tree of life.

	Researchers uncover how PICH protein protects DNA during cell division Researchers at The University of Hong Kong (HKU) have made an exciting discovery about how human cells protect DNA during cell division, offering new insights into combating diseases such as cancer.

	NIH provides $14 million to support human genome research diversification Washington University School of Medicine in St. Louis has received two large grants renewing funding for the Human Pangenome Reference Sequencing Project.

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