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The latest genomics news from News Medical |
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![[Free Webinar] Enabling High Throughput Data Processing in Life Sciences Lab Environments](https://www.azonetwork.com/newsletters/images/generic/210__639153674364586466_multisizecolor_0_custom.jpg) [Free Webinar] Enabling High Throughput Data Processing in Life Sciences Lab Environments
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|  | | | | |  How multi-omics is changing what scientists can see in the human immune system Human systems immunology is using multi-omics, single-cell tools, spatial technologies, and AI to decode immune responses across real-world human cohorts. The review highlights major opportunities for biomarker discovery and precision medicine, while stressing the need for rigorous study design, validation, and careful interpretation. | |  | | | | |  New Pipeline Sharpens Single-Cell Profiling of CAR Immune Therapies CERTOMICS is a Nextflow-based computational pipeline designed to identify and profile CAR-engineered immune cells using single-cell multiomics data. By integrating gene expression, immune receptor profiling, protein markers, CAR-aware references, and CAR-specific quality control, it supports more standardized analysis of adoptive cellular immunotherapies. | | | | | | |  Genetic background shapes outcomes in chromosome 16 deletion disorders Individuals that share the same deletion of a portion of chromosome 16 are at risk of developing neurodevelopmental disorders, but some experience severe intellectual disability or developmental delay, while others may only exhibit milder psychiatric features like depression or anxiety. | | | | | | |  DNA-guided CRISPR system targets RNA and expands Cas12 beyond gene editing Researchers developed ψDNA, a DNA-based CRISPR guide that allows Cas12 enzymes to target RNA with high specificity while retaining compatibility with DNA-editing workflows. The platform detected HCV RNA in clinical samples and enabled programmable RNA knockdown, multiplex targeting, and RNA modification in human cells. | |
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