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   AI for Decoding Gene Expression and Cellular BehaviorAI for Decoding Gene Expression and Cellular Behavior
 
AI is being used to model gene regulation and predict cellular behavior from transcriptomic data. Learn how these tools aid discovery in biology, medicine, and synthetic biology—along with key ethical concerns.
 
   New hereditary condition impairs DNA repair and raises blood cancer riskNew hereditary condition impairs DNA repair and raises blood cancer risk
 
A new hereditary condition has been discovered that affects patients' ability to repair DNA – leaving them both at greater risk of developing blood cancer, and unable to repair some of the damage caused by chemotherapy treatments.
 
 Stanford study identifies gene signature that predicts immune health
 
Stanford study identifies gene signature that predicts immune healthAt the start of the COVID-19 pandemic, information began to trickle in about who was at higher risk of a dangerous outcome from infection. Men. Those over 65. Smokers. Those with obesity.
 
 
 Full tumor DNA sequencing becomes standard for children with cancer
 
Full tumor DNA sequencing becomes standard for children with cancerReadouts of the full DNA of children with cancer at diagnosis have been implemented as the standard of care in a European first.
 
 
 Yale researchers triple precision and efficiency in genome editing
 
Yale researchers triple precision and efficiency in genome editingThe promise of genome editing to help understand human diseases and create new therapies is vast, but technological limitations have limited advancement of the field.
 
 
 New gene therapy strategy reactivates dormant genes to treat blood disorders
 
New gene therapy strategy reactivates dormant genes to treat blood disordersResearchers have found a promising new method for gene therapy. They successfully restarted inactive genes by bringing them closer to genetic switches on the DNA called enhancers.
 
 
 Mass photometry recognized by U.S. Pharmacopeia in new AAV reference standards for gene therapy quality
 
Mass photometry recognized by U.S. Pharmacopeia in new AAV reference standards for gene therapy qualityRefeyn, the company behind pioneering mass photometry technology, announces that mass photometry has been recognized by the U.S. Pharmacopeia (USP)—and referenced in the new draft USP general chapter —as a key orthogonal method for characterizing USP's new adeno-associated virus (AAV) reference standards.
 
 
 Herpes virus reshapes the human genome's architecture to aid its replication
 
Herpes virus reshapes the human genome's architecture to aid its replicationViruses are entirely dependent on their hosts to reproduce. They ransack living cells for parts and energy and hijack the host's cellular machinery to make new copies of themselves.
 
 
 Why Alzheimer’s DNA tests don’t treat all populations equally
 
Why Alzheimer’s DNA tests don’t treat all populations equallyA major global study tested whether European-derived polygenic risk scores (PGS) for Alzheimer’s disease can predict risk across diverse populations. While PGS performed well in many groups, it was less accurate in individuals of sub-Saharan African and Indian ancestry, highlighting the urgent need for more inclusive genetic data.
 
 

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