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The latest genomics news from News Medical |
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 Streamlining CRISPR workflows, from editing to analysis
CRISPR gene editing is a valuable tool that can be used to modify, delete or correct specific regions of DNA. INTEGRA Biosciences has collaborated with biotechnology companies DropGenie and QUiCKR Bio to create efficient automated solutions that take advantage of the full liquid handling portfolio.
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 Closing the Loop in Allogeneic CAR-T Manufacturing: An Integrated Electroporation Workflow
The development of allogeneic CAR-T therapies requires efficient, scalable manufacturing processes that reduce manual intervention and minimize open handling.
The presentation will also highlight key process development considerations, including cell recovery and viability, gene-editing efficiency, workflow integration, and scalability. Together, these results demonstrate an integrated, functionally closed approach that streamlines allogeneic CAR-T manufacturing, improves reproducibility, and reduces open handling.
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| |  | | | | |  Single-Molecule Optical Tweezers Visualize Real-Time Dynamic Protein and DNA Interactions A protein that's essential to every cell's ability to turn off unnecessary genes is well known for its key function of compacting genes and its connection to cancer when it undergoes mutation. But until now, scientists weren't quite sure how the protein gets where it needs to go to keep genes bound up so they aren't activated. | |
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|  | | |  A protein that's essential to every cell's ability to turn off unnecessary genes is well known for its key function of compacting genes and its connection to cancer when it undergoes mutation. | | | | |  Mitochondria are small organelles within cells that play a central role in vital cellular processes, especially energy production. | | | | |  Octopuses, squid and cuttlefish, collectively known as coleoid cephalopods, have evolved exceptionally large and elaborately structured nervous systems capable of complex behaviors such as problem-solving and rapid camouflage. | | | | |  The transmission of biological traits from one generation to the next is generally attributed to DNA. But could some changes be passed on without altering the DNA sequence? | | | | |  Chronic night shifts alter circadian gene activity in female healthcare workers. | | | | |  Researchers at the University of Liège have used imaging-based spatial single-cell transcriptomics to map the cellular organization of lungs from people who died with severe COVID-19. | | | | |  Canavalia gladiata, commonly known as sword bean, is a leguminous crop with high seed protein content (26%–30%) and oil rich in unsaturated fatty acids. Despite its nutritional promise, the species has remained underutilized, largely because a complete genome and the genetic basis of its nutritional traits were lacking. | | | | |  Bolting time is a critical agronomic trait in Brassica campestris. Once the plant shifts from producing edible leaves to flowering, leaf production ceases, leading to rapid deterioration of yield and quality. | | | | |  A tumor suppressor gene known as p53 is mutated in more than half of all cancers, but how it acts to prevent cancer formation is largely unknown. | |
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