Genomics - CRISPR off-switch discovered: Safer gene editing for future therapies |
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The latest genomics news from News Medical |
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Innovative Modules Enhance Magnetic Bead Purification Workflows
What do PCR clean-up, NGS library prep size selection, nucleic acid extraction, and targeted protein enrichment protocols have in common? They can all be accomplished with magnetic beads and require repetitive pipetting steps that are tiring to perform manually. The newly launched MAG and HEATMAG modules allow efficient, hands-free magnetic bead purification by automatically collecting magnetic beads. These magnetic devices are complemented by COLDPLATE and BIOSHAKE modules – providing precise temperature control and orbital shaking, respectively – to streamline workflows and level up productivity significantly.
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| | | | Mayo Clinic researchers studying the genetics of people who had recently developed dilated cardiomyopathy, one of the most common causes of heart failure, have found a particular gene to target for developing future drug therapy treatments. | | | | A team of researchers at the Carl Gustav Carus Faculty of Medicine, TUD Dresden University of Technology, led by Prof. Frank Buchholz, has achieved a major breakthrough in genome editing technology. | | | | The aim of this clinical trial, which has just received approval in France, is to assess the safety and efficacy of a new gene therapy drug in children aged between 6 and 31 months with profound hearing loss. | | | | More than one hundred key genes linked to DNA damage have been uncovered through systematic screening of nearly 1,000 genetically modified mouse lines, in a new study published on 14 February in Nature. | | | | The recent approval of a CRISPR-Cas9 therapy for sickle cell disease demonstrates that gene editing tools can do a superb job knocking out genes to cure hereditary disease. | | | | Genetic drift is one of the four main factors associated with changes in the gene pool over time. Other factors that lead to genetic changes are mutation, natural selection, and gene flow. This article focuses on genetic drift and its consequences. | |
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