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The latest genomics news from News Medical |
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 Magnetic beads represent a modern approach to gDNA isolation
Magnetic bead-based isolation protocols operate through a series of pipetting steps for lysis, binding, washing and elution – using magnetic separation to isolate the nucleic acids of interest.
Unlike traditional spin column-based purification methods, magnetic bead-based workflows do not rely on cumbersome centrifugation or vacuum manifolds to bind and elute nucleic acid, making them ideal for automated DNA isolation protocols.
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 Automating NGS Library Preparation
As sequencing costs fall and throughput increases, library preparation remains a critical step in achieving reliable NGS results. This eBook introduces approaches for miniaturizing and automating NGS library prep using low-volume liquid handling solutions designed to improve workflow efficiency, sample preservation, coverage, and sequencing depth.
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| |  | | | | |  Scientists uncover shared gene signatures that reveal how mammals age Researchers mapped more than 11,000 transcriptomes across mice, rats, macaques, and humans, revealing conserved molecular signatures of aging and mortality across tissues, species, and cell types. The study developed interpretable transcriptomic clocks that track age, mortality-related molecular change, chronic disease signals and responses to lifespan-altering interventions. | |
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|  | | |  Emerging gene editing platforms are revolutionizing precision medicine, enabling safe and effective genetic modifications for diverse therapeutic applications. | | | | |  Advancements in AI, genomic surveillance, and CRISPR are revolutionizing outbreak preparedness and response, enhancing global health security against pandemics. | | | | |  Researchers at Cornell University have developed a safer and more precise way to study how genes function in living tissues by refining a recently developed CRISPR-based genetic technique in fruit flies, enabling researchers to better study how genes contribute to development and disease. | | | | |  DNA is composed of long chains that act as the blueprint for living organisms. In genetic engineering, scientists cut DNA at specific sites and join the resulting fragments to other DNA sequences, enabling applications such as advanced crop breeding, genetic disease treatment, and the generation of animal models for drug discovery. | | | | |  Genes are not passed on exclusively from parents to their offspring. Some are mobile and can also jump to other species, as researchers at the Max Planck Institute for Marine Microbiology in Bremen have now shown. | | | | |  Researchers at Baylor College of Medicine and collaborating institutions are challenging the traditional understanding of how cancer drugs called histone deacetylase (HDAC) inhibitors function. | | | | |  A rapidly advancing area of biomedical innovation is shining a spotlight on miR-128-3p, a small yet powerful molecule with the potential to reshape how diseases—especially cancer—are detected, monitored, and treated. This microRNA, part of a broader class of non-coding RNAs, plays a critical role in regulating gene activity and maintaining cellular homeostasis. | | | | |  Many repetitive regions of the genome have been considered "junk DNA" because the technologies available did not allow them to be studied at sufficient resolution. | |
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