Metabolomics - Discover, Visualize and Identify Biomakers
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#ALT# Development of Biomarkers and Biotherapeutics is Heavily Reliant on Analytical Science

The 1980s saw the introduction of the first biotherapeutic – recombinant human insulin for the treatment of diabetes mellitus (DM). This drug replaced bovine and porcine as sources for this hormone as it had a higher purity, specificity, and efficacy. It was also a more cost-effective source of treatment.

Since then, biotherapeutics have demonstrated high specificity and effectiveness compared to their small, chemical counterparts of the pharmaceutical industry, resulting in a dramatic increase in total annual revenue from $4.4 billion in 1990 to more than $275 billion today.

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    KeysightDiscover, Visualize and Identify Biomakers
 
MetaboScape has a number of features that are beneficial for pharma. One of these is the introduction of the BioTransformer module that enables the prediction of small molecule metabolism. This is metabolism within mammals and from the gut microbiome and the BioTransformer module enables you to annotate associated metabolites from a drug of interest.

In this interview, Lucy Woods, Business Unit Manager for Phenomics and Metabolomics at Bruker Daltonics talks to New-Medical Life Sciences about the new MetaboScape®, all-in-one software for compound identification for non-targeted workflows.

 
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   Fine-tuning stem cell metabolism prevents hair lossFine-tuning stem cell metabolism prevents hair loss
 
A team of researchers have discovered a mechanism that prevents hair loss: hair follicle stem cells.
 
 Analysis of wild tomatoes elucidates genetic basis underlying fruit traits
 
Analysis of wild tomatoes elucidates genetic basis underlying fruit traitsDomestication and subsequent intensive breeding of tomato had a major impact on fruit ripening and the myriad metabolic processes accompanying it.
 
 
 Lipidomics in Food Science
 
Lipidomics in Food ScienceLipids are one of the major components that play a key role in the maintenance of human health.
 
 
 Researchers to explore the role of gut microbes in childhood celiac disease
 
Researchers to explore the role of gut microbes in childhood celiac diseaseBoston College Assistant Professor of Biology Emrah Altindis has received a three-year, $300,000-grant from the G. Harold and Leila Y. Mathers Foundation for research into childhood celiac disease.
 
 
 Metabolites may be predictive indicators for recurrent major depressive disorder
 
Metabolites may be predictive indicators for recurrent major depressive disorderResearchers at University of California San Diego School of Medicine, in collaboration with Dutch scientists, have found that certain metabolites -- small molecules produced by the process of metabolism -- may be predictive indicators for persons at risk for recurrent major depressive disorder.