Go Beyond Quantitation

	Metabolomics
	The latest metabolomics news from AZoNetwork

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			New Single-Cell Technique Reveals Why Bacteria Survive Antibiotics SinBactM's innovative approach to single-bacterium metabolomics reveals distinct metabolic states, enhancing understanding of antibiotic resistance in bacteria.

			How multi-omics is changing what scientists can see in the human immune system Human systems immunology is using multi-omics, single-cell tools, spatial technologies, and AI to decode immune responses across real-world human cohorts. The review highlights major opportunities for biomarker discovery and precision medicine, while stressing the need for rigorous study design, validation, and careful interpretation.

	Gut microbes may reveal why diabetes raises heart disease risk Integrated gut microbiome and plasma metabolomics profiling identified distinct microbial and metabolic signatures in people with T2DM and T2DM-CAD. In a small exploratory cohort, Bacteroides sp._CAG_875 and 12-ketoLCA emerged as candidate markers that may help distinguish diabetic patients with coronary complications, pending larger validation.

	Web-Based Platform Facilitates Chemical Structure Queries in Metabolomics An international team led by researchers at University of California San Diego and University of California, Riverside has developed a free, web‑based platform designed to make public metabolomics data more accessible.

	The Goldilocks sleep zone: study links too little and too much sleep to biological aging The Nature study introduces “Sleep Chart,” a framework linking self-reported sleep duration with 23 biological aging clocks derived from MRI, plasma proteomics, and metabolomics. Across UK Biobank participants, the lowest biological age gaps generally appeared between 6.4 and 7.8 hours of sleep, while shorter and longer sleep were associated with higher disease and mortality risk.

	Blood metabolite patterns could reveal dementia risk in midlife Research shows that blood metabolite profiles can indicate dementia risk, offering a potential tool for early detection and prevention of cognitive decline.

	Higher stress and BMI tied to earlier puberty in girls New research links stress, BMI, and hormone patterns to pubertal timing, revealing implications for long-term health and early intervention strategies.

	Faster biological aging linked to higher dementia risk Having a biological age older than chronological age is associated with a greater likelihood of developing dementia, a new study has shown.

	Researchers uncover sex-specific metabolic patterns in ocular tissues As a highly differentiated sensory organ, the maintenance of the eye's physiological functions relies on rigorous metabolic regulation.

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