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The latest metabolomics news from AZoNetwork |
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 Stop choosing between sensitivity and structural clarity
Discover how advanced workflows combine triple quadrupole–grade sensitivity with deep structural insight, resolving isomers, enabling confident bile acid identification, and quantifying oxylipins at sub‑pg levels in a
single streamlined approach.
Explore where quantitation meets structural clarity.
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| |  | | |  This study shows that specific ratios of circulating sphingolipids to steroids can predict the risk of future asthma exacerbations over five years with high discriminatory performance. By integrating metabolomics with longitudinal medical records, the research highlights lipid–hormone pathway imbalance as a key driver of asthma instability. | | | | |  More than two hundred metabolic enzymes, many of which are normally tasked with producing energy in the mitochondria, are also found sitting directly on top of human DNA, according to a study published today in Nature Communications. | | | | |  This large prospective study integrated blood metabolomics, genetics, and lifestyle data to identify hundreds of metabolites associated with long-term risk of type 2 diabetes in initially healthy adults. A validated 44-metabolite signature improved risk prediction beyond conventional factors, offering insights into biological pathways and opportunities for earlier, more precise prevention. | | | | |  Researchers at the University of Granada have revealed that the Nutri-Score labeling system, commonly used in Europe to assess food quality, is unable to adequately reflect the nutritional and metabolic complexity of soluble cocoa sold in Spain. | | | | |  Cristina Legido-Quigley shares insights on lipidomics and Alzheimer's disease, focusing on metabolic factors and the importance of women's visibility in STEM. | | | | |  A randomized crossover trial found that replacing red meat patties with processed plant-based meat alternatives for six days significantly lowered circulating trimethylamine N-oxide (TMAO), a gut-derived metabolite linked to cardiovascular risk. The plant-based phase also produced modest reductions in cholesterol markers but slightly increased weight and NT-proBNP, possibly due to higher sodium intake. | | | | |  Acute systemic inflammation has long been suspected to trigger harmful processes within the brain, contributing to neurodegenerative disorders such as Alzheimer's and Parkinson's disease. | | | | |  Researchers engineered E. coli to produce orsellinic acid-derived meroterpenoids, offering a sustainable alternative to traditional plant extraction methods. | | | | |  Researchers used five prospective cohorts from the US and China to identify circulating gut microbiota-related metabolites linked to future coronary heart disease, then tested the findings through discovery, in silico validation, and targeted quantitative validation. The study ultimately highlighted nine metabolites associated with incident CHD, supporting a potential role for microbial metabolism in heart disease risk while not proving causation | |
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