Rice’s SynthX Center leads interdisciplinary effort to tackle rare lymphatic disorders

	Rare Diseases
	The latest rare diseases news from News Medical

	Rice’s SynthX Center leads interdisciplinary effort to tackle rare lymphatic disorders Rice University's SynthX Center, directed by Han Xiao, has received an up to five-year, $18 million award from the Advanced Research Projects Agency for Health (ARPA-H) Lymphatic Imaging, Genomics and pHenotyping Technologies (LIGHT) program to develop innovative solutions for lymphatic diseases.

	New pangenomic approach enables unprecedented scaling for genetic data Researchers at the University of California have created a novel data structure and compression method that allows pangenomics to process genetic information at previously unattainable scales.

	FIU's personalized cancer treatment shows promise Researchers at FIU are advancing a personalized approach to cancer treatment that is showing increasingly promising results for patients with hard-to-treat disease, supported by new philanthropic investment that is helping expand the science behind the work.

			Cancer vaccines enter a new era of personalized immunotherapy A new comprehensive review from researchers at the Icahn School of Medicine at Mount Sinai details how decades of cancer vaccine research are converging into a new era of more precise, personalized, and effective immunotherapies, particularly when combined with other cancer treatments.

			Whole-genome sequencing improves PARP inhibitor treatment prediction A whole-genome sequencing approach shows early promise over current commercial methods for identifying more patients likely to benefit from PARP inhibitor cancer treatments, according to a study led by Weill Cornell Medicine and NewYork-Presbyterian investigators.

	What role does DNA analysis play in modern disease diagnostics? DNA analysis is a crucial tool for identifying harmful pathogens, such as bacteria, viruses, or fungi, that cause infections.

	Unraveling liver injury mechanisms in familial hypobetalipoproteinemia Familial Hypobetalipoproteinemia (FHBL), caused by variants in the apolipoprotein B (APOB) gene, is a rare autosomal co-dominant monogenic disorder characterized by lifelong low plasma levels of total cholesterol, low-density lipoprotein cholesterol (LDL-C), and APOB.

	DLL3 on circulating tumor cells predicts tarlatamab success in lung cancer A team led by investigators at the Mass General Brigham Cancer Institute has discovered that a particular marker on tumor cells circulating in the blood indicates whether a patient with lung cancer will experience a lasting response to a newly approved immunotherapy called tarlatamab.

	UT Southwestern performs first regional whole-liver chemotherapy for rare eye cancer A team at UT Southwestern Medical Center this week became the first in Texas and neighboring states to successfully perform a novel procedure to deliver whole-liver chemotherapy to treat metastatic uveal melanoma, a rare and deadly eye cancer.

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