| |  Immunohistochemistry (IHC) is a popular method for visualizing the presence, concentration, and distribution of molecules within tissue. The method utilizes specific antibodies that bind to target antigens and is a very effective way of studying tissue architecture. However, cross-reactivity, low specificity and problems with antibody preparation can cause serious issues with background noise. | |
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| |  Host-cell enzymes called PARP12 and PARP14 are important for inhibiting mutant forms of a coronavirus, according to a study published May 16 in the open-access journal PLOS Pathogens by Stanley Perlman of the University of Iowa, Anthony Fehr of the University of Kansas, and colleagues. | |
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| |  The cGAS–STING pathway is part of the innate immune system and is involved in the detection of cytosolic deoxyribonucleic acid (DNA). Post-detection, this pathway triggers the defense mechanisms that can lead to cell senescence. | |
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| |  A discovery of how stem cells are protected from viruses could inform the development of therapies for use in medicine, research suggests. The finding could help research aimed at boosting the immune response of stem cells - early stage cells with the potential to become specialized tissues - for use in treating disease or damaged tissues. | |
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| |  Researchers in Switzerland have conducted a review of studies looking at how circadian rhythm affects the immune response and severity of illnesses ranging from heart attack to allergy. | |
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| |  A new gene therapy created by US researchers appears to have cured eight infant boys born with a rare genetic disorder referred to as “Bubble Boy” disease. The new therapy was shown to safely correct the immune systems of eight infants affected by X-linked severe combined immunodeficiency (X-SCID). | |
