Immunology - What is Adoptive Cell Therapy?
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   What is Adoptive Cell Therapy?What is Adoptive Cell Therapy?
 
Cellular immunotherapy, or adoptive cell therapy, is an innovative treatment approach that uses the cells of our immune system to fight cancer.
 
   Ultrapotent IgM antibodies isolated from a pregnant woman with Zika virus show promise as an immunotherapyUltrapotent IgM antibodies isolated from a pregnant woman with Zika virus show promise as an immunotherapy
 
Zika virus (ZIKV) infection is a potentially teratogenic illness, causing up to one in seven infants born to infected mothers to suffer neurodevelopmental deficits. A new study published in the journal Cell shows that some mothers escape injury to their babies because they develop a highly potent neutralizing antibody.
 
 Bispecific antibodies neutralize Sarbecoviruses with increased breadth and potency
 
Bispecific antibodies neutralize Sarbecoviruses with increased breadth and potencyIn a recent study posted to the bioRxiv* preprint server, researchers developed bispecific antibodies (bsAbs), neutralizing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants.
 
 
 SARS-CoV-2 antibodies persist in breast milk following two and three COVID-19 vaccine doses
 
SARS-CoV-2 antibodies persist in breast milk following two and three COVID-19 vaccine dosesA new study assesses anti-SARS-CoV-2 antibody levels in breast milk obtained from lactating individuals following two or three COVID-19 vaccine doses.
 
 
 Study of natural killer lymphocytes transcriptionally reprogrammed by vaccinia virus
 
Study of natural killer lymphocytes transcriptionally reprogrammed by vaccinia virusIn a recent study posted to the bioRxiv* preprint server, researchers evaluated responses of natural killer (NK) lymphocytes to VACV (vaccinia virus) infections in vivo.
 
 
 Atypical antibody shows extremely potent zika-resistant activity
 
Atypical antibody shows extremely potent zika-resistant activityA group of researchers led by Weill Cornell Medicine, New York-Presbyterian, and National Institutes of Health (NIH) investigators has discovered an unusual type of antibody that, even at extremely low concentrations, neutralizes the Zika virus and renders the virus infection undetectable in preclinical models.
 
 
 Unusual Zika virus-specific antibody exhibits ultrapotent neutralization
 
Unusual Zika virus-specific antibody exhibits ultrapotent neutralizationAn unusual type of antibody that even at miniscule levels neutralizes the Zika virus and renders the virus infection undetectable in preclinical models has been identified by a team led by Weill Cornell Medicine, NewYork-Presbyterian and National Institutes of Health (NIH) investigators.
 
 
 Immunological responses against monkeypox virus concerning the 2022 outbreak
 
Immunological responses against monkeypox virus concerning the 2022 outbreakA new study aimed to analyze the kinetics of the pox-specific T-cell induction, the inflammatory profile, and the inflammatory profile in human cases of the current monkeypox outbreak.
 
 
 Plant-based monoclonal antibody increases potency of antibody cocktail against SARS-CoV-2 Omicron variant
 
Plant-based monoclonal antibody increases potency of antibody cocktail against SARS-CoV-2 Omicron variantA novel mAb against the SARS-CoV-2 RBD through a hybridoma technique, followed by chimerization and expression in plants.
 
 
 Empty lipid nanoparticles trigger maturation and activation of antigen-presenting cells
 
Empty lipid nanoparticles trigger maturation and activation of antigen-presenting cellsIn a recent study posted to the Research Square* preprint server and under review at the Nature Portfolio journal, researchers reported activation and maturation of antigen-presenting cells (APCs) by lipid nanoparticles (LNPs).
 
 
 Comprehensive analysis outlines the potential toxicities of antibody drug conjugates
 
Comprehensive analysis outlines the potential toxicities of antibody drug conjugatesOver the past two decades, numerous complex cancer therapies called antibody drug conjugates (ADCs) have been tested in clinical trials and approved for use in patients.