Men's Health - Dec 5, 2023 - Link between stress and autoimmunity

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	Men's Health
	The latest men's health news from News Medical

	Link between stress and autoimmunity: New insights into depression from mice to humans Study investigates the link between stress and autoimmunity, finding a correlation between higher levels of serum and brain-reactive antibodies and depression-like behaviors in mice and humans with Major Depressive Disorder.

	Can loneliness lead to diabetes? New study reveals the role of physical activity and BMI Study investigates the relationship between loneliness and diabetes, finding that physical activity and BMI mediate this link, but diet quality does not. It highlights the complex interplay between loneliness, lifestyle factors, and diabetes risk, underscoring the need for targeted interventions to improve both mental and physical health.

			Two kiwi fruit every day safe and can replace vitamin C supplementation Study investigates the health effects of consuming two kiwifruits daily for six weeks. It finds no significant changes in metabolic and inflammatory biomarkers, indicating that regular kiwifruit consumption is safe and increases dietary vitamin C intake without adversely affecting metabolic health.

			Bivalent COVID-19 boosters offer stronger protection for seniors, Australian study reveals Study compares the effectiveness of bivalent and monovalent booster vaccines against COVID-19 mortality in individuals aged 65 and older. It finds that bivalent boosters show higher vaccine effectiveness against COVID-19 mortality, particularly for the Omicron variant, compared to monovalent vaccines.

			Study finds long-COVID symptoms fluctuate over time, challenging treatment approaches Study reveals that over half of long Covid patients experience fluctuating symptom severities over time, highlighting the dynamic nature of the condition. The research underscores the need for adaptive healthcare interventions and self-management strategies, considering these symptom variations in long Covid cases.

	Mapping emotions in the body: Study reveals physical topography of feelings The study published in PNAS reveals that emotions create identifiable maps of bodily sensations, consistent across different cultures and races. Using a novel method named "embody," researchers found that subjective emotional experiences are linked to specific bodily changes, providing insights that could aid in understanding and treating mood disorders like depression and anxiety, which alter standard emotional processing.

	Study finds racial disparity in the utilization of crucial prostate cancer therapy A new study led by investigators at the UCLA Health Jonsson Comprehensive Cancer Center found Black men diagnosed with more advanced stages of prostate cancer are significantly less likely to be prescribed novel hormone therapy than other racial and ethnic groups – including white or Latino men – despite the therapy being proven to effectively control the growth of prostate tumors and extend the lives of men with the disease.

	Omega-3s in the spotlight: The impact of EPA and DHA on athlete health and performance Research paper reviews the effects of omega-3 fatty acids, EPA, and DHA, on athletes, discussing their benefits in inflammation control, cognitive function, and muscle maintenance, and the need for further research to fully understand their impact. It also addresses the risks and optimal intake of these supplements, highlighting their potential to improve athletic performance and recovery with minimal adverse effects at recommended doses.

	Science tackles mental health: New tools against anxiety and depression in a stressed world This review in the Proceedings of the National Academy of Sciences discusses the role of scientific tools in combating mental health disorders like anxiety, MDD, and PTSD, emphasizing the need for a deep scientific understanding and diverse treatment approaches in the face of a global surge in psychological stress.

	AI transforms colonoscopy: Boosting detection rates, slashing miss rates in cancer screening Researchers in China have demonstrated through a systematic review and meta-analysis that AI-based methods significantly enhance adenoma detection rates and reduce miss rates during colonoscopies, potentially improving colorectal cancer screening and reducing mortality.

	Hormone therapy for transmasculine individuals may be safer than previously thought A common concern about gender-affirming hormone therapy for transmasculine people is the risk of red blood cell volume changes and erythrocytosis, a high concentration of red blood cells, with the use of prescribed testosterone.

	Genetic mutation in OXR1 gene linked to brain development issues Study investigates the effects of a loss-of-function mutation in the OXR1 gene on neurodevelopment and cellular functions in the human brain. The research shows that OXR1 deficiency impairs neural differentiation, increases sensitivity to oxidative stress, and alters histone methylation, impacting brain development and potentially contributing to neurological disorders.

	UK Biobank data opens door to new era of precision medicine In a momentous landmark for medical research, UK Biobank has today [Thursday 30 November] unveiled incredible new data from whole genome sequencing of its half a million participants.

	Exploring 'food noise': Study sheds light on eating thoughts and obesity treatment breakthroughs Study delves into the concept of 'food noise,' referring to persistent thoughts about eating, and assesses its impact on eating behaviors and obesity treatments. It explores how GLP-1RAs, a class of drugs used for weight management, might influence food cue reactivity, potentially offering new insights into obesity treatment and the psychological aspects of eating behaviors.

	Decoding anxiety: Study reveals brain's role in behavioral inhibition risks Researchers in the U.S. used non-human primate models to explore the molecular mechanisms and neural systems behind behavioral inhibition, a key risk factor for anxiety disorders. The study identified molecular systems in the posterior orbitofrontal cortex linked to variations in anxious temperament, offering potential targets for treating anxiety disorders.

	New study provides convincing evidence of the essential role of cylicins in sperm development and fertility Researchers investigated the Role of Cylicins in Spermiogenesis and Male Fertility in Mice and Humans through Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/ CRISPR-associated protein 9 (Cas9) Gene Editing.

	Fruit fly study reveals potential trigger for growth cessation All animals start out as a single-celled organism and then start growing. At some point, of course, they need to stop getting bigger, but the process by which this happens is poorly understood.

	UK Biobank unveils world's largest genetic data set In a momentous landmark for medical research, UK Biobank has today [Thursday 30 November] unveiled incredible new data from whole genome sequencing of its half a million participants.

	Greater adherence to lifestyle-based recommendations reduced the risk of cancers in the U.K. The BMC Medicine study confirms that adhering to the 2018 World Cancer Research Fund/American Institute for Cancer Research recommendations significantly lowers the risk of various cancers, including breast, colorectal, and esophageal, in the UK population. This highlights the importance of lifestyle choices in cancer prevention.

	Major UK study finds high demand and efficacy for HIV PrEP among sexual health service attendees HIV PrEP requirement, duration, uptake, and usage among sexual health services (SHS) attendees in England.