Closing the Loop in Allogeneic CAR-T Manufacturing: An Integrated Electroporation Workflow

	Cell & Gene Therapy
	The latest stem cells news from News Medical

In this webinar, we’ll explore the development of an integrated manufacturing workflow combining automated cell processing, gene editing, cell expansion, and final product processing.

The presentation will also highlight key process development considerations, including cell recovery and viability, gene-editing efficiency, workflow integration, and scalability. Together, these results demonstrate an integrated, functionally closed approach that streamlines allogeneic CAR-T manufacturing, improves reproducibility, and reduces open handling.

Book your place now

			Huge philanthropic grant funds pioneering stem cell-based heart attack therapy In a landmark moment for both the treatment of heart disease and philanthropic support, The Marcus Foundation has awarded the head of USC Stem Cell Center, Chuck Murry, MD, PhD, $28.7 million to advance a clinical trial testing a stem cell-based therapy designed to regenerate damaged tissue after a heart attack.

			New review urges proteostatic fitness standards for stem cell therapies Stem cell therapies have expanded rapidly, with more than 115 clinical trials involving over 1,200 patients approved by late 2024. The U.S. Food and Drug Administration (FDA) recently approved Ryoncil (remestemcel‑L) for children with steroid‑refractory acute graft‑versus‑host disease, signaling a major shift toward routine clinical use.

	Scalable stem cell method advances off-the-shelf CAR-T therapies Researchers at the Center for Regenerative Medicine (CReM) at Boston Medical Center (BMC) and Boston University (BU) have developed a scalable method for generating CD4+ helper T cells from induced pluripotent stem cells (iPSCs), overcoming a longstanding challenge in the development of stem cell-based immunotherapies.

	EpilepsyGTx and Viralgen collaborate to advance AAV gene therapy program for epilepsy ahead of first-in-human trial EpilepsyGTx, a biotechnology company developing gene therapies for refractory epilepsy, and Viralgen, a leading contract development and manufacturing organization (CDMO) specializing in recombinant adeno-associated virus (AAV) gene therapies, today announced a partnership to support production of EpilepsyGTx's lead investigational gene therapy program targeting patients with focal refractory epilepsy (FRE), EPY201, ahead of first-in-human...

	Immune-shielded iPSC islet cells for diabetes Explore immune-shielded iPSC-derived islet-like clusters for type 1 diabetes cell therapy.

	Scientists map key differences in stem cell potency for treating knee osteoarthritis Knee osteoarthritis (KOA) affects more than 1 in 10 people over 40 years of age, impairing patients' mobility and quality of life.

	CAR T-cell therapy successfully reverses severe rheumatoid arthritis Immunotherapies such as CAR T-cell therapy are used primarily to treat cancer. In the future, these patient-specific therapies, manufactured from patients' own immune cells, could also help cure autoimmune diseases.

	In vivo CAR-T therapy transforms customized treatments into universal medicines A collaborative team led by Professor Huji Xu from Naval Medical University, China, together with Professors Xuanming Yang and Yujia Cai at Shanghai Jiao Tong University, China, published a comprehensive review in Volume 2, article number 33 of the journal Immunity & Inflammation on August 31, 2026.

	PIWI proteins and piRNAs may unlock more effective stem cell therapies Scientists are shedding new light on a little-known biological system that could help unlock the full potential of stem cell therapy, one of the most promising areas of modern medicine.

	New Computational Tool Estimates Cell Age by Analyzing Gene Activity Patterns Scientists at Karolinska Institutet and Stockholm University have created an innovative tool that determines cellular biological age through gene activity analysis.

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