Stem Cells - BGMP Ancillary Materials for Stem Cell Therapy Manufacture
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#ALT# Inducing Plasticity in hiPSC-Derived Cortical Neurons

Plasticity such as long-term potentiation depression (LTD) and long-term potentiation (LTP) in neuronal networks has been examined using in vivo and in vitro methods in simple animals to figure out development, memory and learning in brain function.

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    KeysightGMP Ancillary Materials for Stem Cell Therapy Manufacture
 
Ancillary materials, used in the manufacture of stem cell therapies, influence the quality, safety and purity of the final cell product for clinical use. It is therefore vital that appropriately qualified materials are used in this process, to mitigate risk to patient safety.
 
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   Brazilian researchers create hepatic organoids by 3D bioprintingBrazilian researchers create hepatic organoids by 3D bioprinting
 
Using human blood cells, Brazilian researchers have succeeded in obtaining hepatic organoids ("mini-livers") that perform all of the liver's typical functions, such as producing vital proteins, storing vitamins, and secreting bile, among many others.
 
 Lab-grown brain organoids may hold the answers to personalized treatments for glioblastomas
 
Lab-grown brain organoids may hold the answers to personalized treatments for glioblastomasLab-grown brain organoids developed from a patient's own glioblastoma, the most aggressive and common form of brain cancer, may hold the answers on how to best treat it. A new study in Cell from researchers at Penn Medicine showed how glioblastoma organoids could serve as effective models to rapidly test personalized treatment strategies.
 
 
 Dresden scientists identify newborn neurons in zebrafish
 
Dresden scientists identify newborn neurons in zebrafishThe zebrafish is a master of regeneration: If brain cells are lost due to injury or disease, it can simply reproduce them - contrary to humans where this only happens in the fetal stage. However, the zebrafish is evolutionarily related to humans and, thus, possesses the same brain cell types as humans.
 
 
 Research adds definitive evidence about how the body's earliest immune cells are formed
 
Research adds definitive evidence about how the body's earliest immune cells are formedOne day the advance could lead to a patient's own skin cells being used to produce new cells for cancer immunotherapy or to test autoimmune disease interventions. The group, led by Professors Ed Stanley and Andrew Elefanty, from the Murdoch Children's Research Institute in Melbourne, Australia, said the work has added definitive evidence about how the body's earliest immune cells are formed.