New genetic map helps track aggressive prostate cancer development
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 Coffee after colorectal cancer? Decaf and caffeine show different links with mortalityCoffee after colorectal cancer? Decaf and caffeine show different links with mortality
 
In a prospective analysis of 1,098 people with colorectal cancer, researchers found no significant association between total or caffeinated coffee intake and all-cause or colorectal cancer-specific mortality in the cohort overall.
 
 
 New genetic map helps track aggressive prostate cancer developmentNew genetic map helps track aggressive prostate cancer development
 
Prostate cancer is the second most common form of cancer among men globally. Yet, we still know relatively little about why the disease develops or why some men live with it for years while in others it progresses aggressively.
 
   Targeted nanoparticles strengthen anti-cancer immune responses in tumorsTargeted nanoparticles strengthen anti-cancer immune responses in tumors
 
Adelaide University researchers have developed a new way of using mRNA technology to reprogram tumor-supporting immune cells and strengthen the body's anti-cancer immune response.
 
   Vitamin A derivative prevents immune cell exhaustion in brain tumorsVitamin A derivative prevents immune cell exhaustion in brain tumors
 
Immune cells can become exhausted after prolonged exposure to cancer, gradually losing their ability to attack tumor cells.
 
   Chronic interferon exposure drives immunosuppression in tumorsChronic interferon exposure drives immunosuppression in tumors
 
Cancer biology and, in turn, cancer treatment have come a long way in the last few decades. Most people recognize this progress in breakthroughs like immunotherapy-a treatment strategy first deployed in 2011 that leverages the body's own immune cells to fight cancer and revolutionized the treatment landscape.
 
 Phase 2 study highlights flexible dosing options for tarlatamab in relapsed SCLC
 
Phase 2 study highlights flexible dosing options for tarlatamab in relapsed SCLCExtended-interval dosing regimens of tarlatamab demonstrated efficacy, safety and pharmacokinetic profiles generally consistent with the established every-two-week regimen in patients with previously treated for small cell lung cancer (SCLC), according to results from the randomized Phase 2 DeLLphi-309 study presented at the International Association for the Study of Lung Cancer (IASLC) 2026 World Conference on Lung Cancer (WCLC).
 
 
 FDA clears trial of dual-targeted CAR T-cell therapy for cancer
 
The U.S. Food and Drug Administration this week granted permission for investigators at the University of Colorado Anschutz to conduct a clinical trial testing genetically engineered immune cells in adults with advanced colorectal cancer and pediatric patients with solid cancers who have exhausted standard treatment options.
 
 
 Is stroke risk higher after a cancer diagnosis?
 
New research indicates that people with invasive cancer face an elevated risk of experiencing a stroke, especially in the first few months after diagnosis and especially if they have certain types of cancer.
 
 
 Cancer treatments alter the landscape of genetic mutations in healthy body tissues
 
Cancer treatments, including chemotherapy and radiotherapy, give a growth advantage to cells with particular genetic changes in healthy tissue, new research finds.
 
 
 Neoadjuvant atezolizumab addition quadruples pathological responses in resectable lung tumors
 
Patients with resectable stage II–IIIB non-small cell lung cancer (NSCLC) treated with perioperative atezolizumab plus platinum-based chemotherapy experienced a median event-free survival of 62.8 months compared with 34.9 months for patients receiving chemotherapy alone, according to final results from the Phase 3 IMpower030 trial.
 
 
 New treatment approach preserves organs, improves survival in head and neck cancer patients
 
Patients with locally advanced head and neck squamous cell carcinoma (HNSCC) whose tumors responded to neoadjuvant immunochemotherapy (ICT) and who underwent less extensive surgery had high disease-free survival and organ preservation rates.
 
 
 New AI tool predicts breast cancer risk using repeated 3D mammograms
 
An artificial intelligence model that analyzes women's past and recent annual 3D mammograms is more effective at predicting five-year risk of developing breast cancer than a tool that uses only the most recent, single 3D mammogram, as well as an AI model that analyzes 2D mammograms, a new study shows.
 
 
 Shortages of crucial cancer medications continue to impact US healthcare
 
Today, the National Comprehensive Cancer Network® (NCCN®)-an alliance of leading cancer centers-published updated data on the current impact of generic cancer medication shortages in the United States.
 
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