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Optimizing Variables for Trial-Ready Liquid BiopsyOptimizing Variables for Trial-Ready Liquid Biopsy

Analytes differ dramatically in stability, susceptibility to pre-analytic variation, and compatibility with blood tubes, centrifugation protocols, processing timelines and storage. This talk provides a practical, cross-analyte framework for clinical, translational, and biomarker teams planning liquid biopsy workflows for early trials, late-phase studies, or real-world research.

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   Vaping devices and flavors affect genes differentlyVaping devices and flavors affect genes differently
 
Vaping exposure affects gene activity in the mouth, with variations linked to device type and flavor, suggesting unique molecular responses compared to smoking.
 
   Could GLP-1 drugs help prevent breast cancer? New study points to a possible linkCould GLP-1 drugs help prevent breast cancer? New study points to a possible link
 
A large retrospective cohort study of 111,646 overweight or obese women found that GLP-1 agonist exposure was associated with lower breast cancer incidence. After propensity-score matching, GLP-1 exposure was linked to nearly 30% lower odds of breast cancer, but the authors stress that randomized trials are needed before these drugs can be considered for prevention.
 
 Three-drug strategy forces pancreatic tumors into lasting regression
 
Three-drug strategy forces pancreatic tumors into lasting regressionA triple-targeted preclinical therapy combining daraxonrasib, afatinib, and SD36 drove durable pancreatic cancer regression by blocking KRAS/RAS, EGFR/HER2, and STAT3 signaling. The approach prevented treatment resistance across mouse and human tumor-derived models, but remains preclinical and requires more clinically suitable drug combinations before human testing.
 
 
 Light-Driven Bismuth Nanomaterials Show Promise Against Tumors and Bacteria
 
Light-Driven Bismuth Nanomaterials Show Promise Against Tumors and BacteriaThis review examines how light-responsive bismuth-based nanomaterials could support CT and photoacoustic imaging, antibacterial therapy, and anticancer treatment. By converting light into heat and reactive oxygen species, these experimental nanoplatforms may enable integrated diagnosis and therapy, although clinical translation still requires stronger biosafety, optical performance, and scalability data.
 
 
 Bispecific Antibodies Target Tumors While Sparing Healthy Tissue
 
Bispecific Antibodies Target Tumors While Sparing Healthy TissueA new generation of bispecific antibodies effectively targets cancer cells, minimizing toxicity and enhancing treatment precision in preclinical studies.
 
 
 Machine learning tool predicts financial toxicity for cancer patients
 
Machine learning tool predicts financial toxicity for cancer patientsResearchers at MUSC Hollings Cancer Center have developed a machine learning tool to identify cancer patients who may be at high risk for financial toxicity – the financial stress and hardship that can accompany a cancer diagnosis and treatment.
 
 
 NYU Langone hits milestone with its 1,000th focal cryotherapy procedure
 
NYU Langone hits milestone with its 1,000th focal cryotherapy procedureJust two days after his minimally invasive prostate cancer treatment at NYU Langone Health, Broadway performer André De Shields, 80, was back onstage preparing for his next show, Cats: The Jellicle Ball, which debuted in April 2026.
 
 
 GLP-1 medications linked to lower breast cancer risk in women
 
GLP-1 medications linked to lower breast cancer risk in womenA retrospective analysis of more than 110,000 women between the ages of 45 and 80 found that those who took GLP-1 medications were about 30 percent less likely to develop breast cancer than those who did not take GLP-1 medications, according to research presented today at the 2026 American Society of Clinical Oncology (ASCO) Annual Meeting (Abstract 10506) by Elizabeth McDonald, MD, PhD, a professor of Radiology in the University of Pennsylvania...
 
 
 First-in-class cancer drug gamitrinib evaluated in phase 1 clinical trial
 
First-in-class cancer drug gamitrinib evaluated in phase 1 clinical trialCancer cells need large amounts of energy to survive and multiply. To produce that energy, they rely on structures inside the cell called mitochondria, often described as the cell's "powerhouse."
 
 

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