Pathology AI models show demographic bias in cancer diagnosis
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 Metabolic reprogramming and immune crosstalk in the tumor microenvironmentMetabolic reprogramming and immune crosstalk in the tumor microenvironment
 
Metabolic reprogramming in the tumor microenvironment shapes immune function and therapy resistance, offering insights into improving cancer immunotherapy.
 
 
 Pathology AI models show demographic bias in cancer diagnosisPathology AI models show demographic bias in cancer diagnosis
 
Pathology has long been the cornerstone of cancer diagnosis and treatment. A pathologist carefully examines an ultrathin slice of human tissue under a microscope for clues that indicate the presence, type, and stage of cancer.
 
   Study identifies TAK1 gene as a key brake on cancer immunotherapyStudy identifies TAK1 gene as a key brake on cancer immunotherapy
 
Australian researchers have discovered that the TAK1 gene helps cancer cells survive attack from the immune system, revealing a mechanism that may limit the effectiveness of immunotherapy treatments.
 
   Combination therapy shows promise to treat a rare, catastrophic pediatric brain cancerCombination therapy shows promise to treat a rare, catastrophic pediatric brain cancer
 
St. Jude Children's Research Hospital scientists identified a promising combination approach to treat a rare, but catastrophic pediatric brain cancer called atypical teratoid rhabdoid tumor (ATRT).
 
   Novel mRNA therapy rejuvenates immune function in aging miceNovel mRNA therapy rejuvenates immune function in aging mice
 
Can the weakened immune systems of older individuals be rejuvenated? Researchers from the German Cancer Research Center (DKFZ), the HI-STEM institute, and the Broad Institute have demonstrated that this is possible with an innovative approach.
 
 THC products provide small improvements in pain but carry side effects
 
THC products provide small improvements in pain but carry side effectsA new systematic evidence review finds that cannabis products that carry relatively high levels of the psychoactive compound tetrahydrocannabinol, commonly known as THC, may provide short-term improvements in pain and function.
 
 
 HPV vaccination reduces risk of vulvar and vaginal lesions
 
HPV vaccination reduces risk of vulvar and vaginal lesionsGirls who are vaccinated against HPV are not only well protected against cervical cancer; they are also less likely to develop severe precancerous lesions of the vulva and vagina, particularly if they were vaccinated before the age of 17.
 
 
 Financial barriers drive low participation in cancer clinical trials
 
Financial barriers drive low participation in cancer clinical trialsA study by Case Western Reserve University and University Hospitals researchers has overturned long-held assumptions about why more cancer patients don't enroll in clinical trials that could potentially save their lives.
 
 
 Nicotine pouch use rises sharply among young men in Great Britain
 
Nicotine pouch use rises sharply among young men in Great BritainUse of nicotine pouches has risen substantially in Great Britain over the last five years, particularly among young men, with one in 13 (7.5%) men aged 16 to 24 now using them, according to a new study led by researchers at UCL (University College London).
 
 
 Scientists unravel how citrin deficiency can trigger fat buildup in the liver even in lean individuals
 
Scientists unravel how citrin deficiency can trigger fat buildup in the liver even in lean individualsScientists at City of Hope, one of the largest and most advanced cancer research and treatment organizations in the U.S. and a leading research center for diabetes and other life-threatening illnesses, have unraveled how citrin deficiency (CD), a rare genetic disorder that prevents the liver from converting food into energy efficiently, can trigger fat buildup in the liver - even in lean individuals.
 
 
 New diagnostic chip enables rapid monitoring of brain cancer treatment
 
New diagnostic chip enables rapid monitoring of brain cancer treatmentNew diagnostic chip pulls packets released from tumor cells out of blood, showing whether cancer cells died during chemotherapy infusion.
 
 
 Strong heart health lowers long-term death risk in cancer survivors
 
Strong heart health lowers long-term death risk in cancer survivorsHigher Life’s Simple 7 cardiovascular health scores were associated with lower long-term all-cause and cancer mortality in cancer survivors from a large Italian cohort. Inflammation, resting heart rate, and vitamin D statistically explained a substantial share of these associations, supporting shared cardiometabolic pathways across cancer and cardiovascular disease.
 
 
 Remodeling the tumor microenvironment to unlock CAR-T cell potential
 
Remodeling the tumor microenvironment to unlock CAR-T cell potentialChimeric antigen receptor T (CAR-T) cell therapy has revolutionized hematologic cancer treatment, but its efficacy in solid tumors remains limited by poor infiltration into the complex tumor microenvironment (TME).
 
 
 Study links low physical activity to higher lymphedema risk after cancer treatment
 
Study links low physical activity to higher lymphedema risk after cancer treatmentLymphedema after head and neck cancer is considerably more common than previously assumed and can persist long after cancer treatment has finished.
 
 
 DNA twisting controls how cells respond to estrogen
 
DNA twisting controls how cells respond to estrogenEstrogens, the main female sex hormone, although they also perform some functions in men, are involved in a myriad of processes, which is why the body changes so much during menopause. This is because estrogens regulate hundreds of genes.
 
 
 Fatty diets reprogram hepatocytes and increase liver cancer risk
 
Fatty diets reprogram hepatocytes and increase liver cancer riskOne of the biggest risk factors for developing liver cancer is a high-fat diet. A new study from MIT reveals how a fatty diet rewires liver cells and makes them more prone to becoming cancerous.
 
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