| Oncology - Simple exercises can prevent nerve damage during cancer treatments |
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The latest oncology news from News Medical |
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 Developing Assays for Measuring RNA Helicase Activity
RNA helicases are a group of enzymes that bind to and alter RNA in an ATP-dependent way. They play significant roles in RNA metabolism, gene expression regulation, and innate immunity. Different RNA helicases, particularly those in the dead box helicase (DDX) family, are dysregulated in cancer; however, there have been very few attempts to produce small molecule inhibitors. Learn how BellBrook Labs used the Transcreener ADP² Assay to develop HTS assays for DDX3, DDX5, DDX17, RIG-I, and MDA5. The assays were developed to accelerate the discovery of selective helicase inhibitors.
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| | |  With the number of adult cancer survivors in the United States expected to reach 23 million by 2032, the long-term needs of this population are growing yet often poorly understood and addressed. | | | | |  Pancreatic cancer is a particularly aggressive and difficult-to-treat cancer, in part because it is often resistant to chemotherapy. | | | | |  The Mediterranean Diet is a powerful ally for health even after a cancer diagnosis. This is the key result of an Italian study carried out as part of the UMBERTO Project, conducted by the Joint Research Platform Umberto Veronesi Foundation - Department of Epidemiology and Prevention of the I.R.C.C.S. Neuromed of Pozzilli, in collaboration with the LUM "Giuseppe Degennaro" University of Casamassima (BA). | | | | |  Researchers found that neuromuscular training significantly reduces the incidence and severity of chemotherapy-induced peripheral neuropathy, improving patient quality of life and treatment outcomes. | |
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