Next-generation CAR T therapy offers hope but faces clinical challenges
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 Mental health struggles in first year of cancer care predict worse outcomesMental health struggles in first year of cancer care predict worse outcomes
 
This study reveals a strong association between early mental health disorders in cancer patients and increased all-cause mortality, highlighting care needs.
 
 
 Next-generation CAR T therapy offers hope but faces clinical challengesNext-generation CAR T therapy offers hope but faces clinical challenges
 
A new editorial perspective was published in Volume 17 of Oncotarget on February 20, 2026, titled "CAR-T therapy: Trailblazing CAR(ing) in cancer treatment."
 
   Global breast cancer burden rising fastest in low-income countriesGlobal breast cancer burden rising fastest in low-income countries
 
Despite recent advancements in breast cancer treatments, new breast cancer cases in women are predicted to rise by a third globally from 2.3 million in 2023 to more than 3.5 million in 2050.
 
   New approach to reducing radiation toxicityNew approach to reducing radiation toxicity
 
Radiation therapy is highly effective at killing cancer cells, but it often harms healthy skin around the treatment area, a common side effect experienced by up to 95% of cancer patients undergoing treatment. In worst-case scenarios, it can result in delayed or halted treatment.
 
   Fifteen-year follow up reveals cure potential in follicular lymphomaFifteen-year follow up reveals cure potential in follicular lymphoma
 
Unlike some other forms of lymphoma, advanced stage follicular lymphoma is considered incurable. But a new analysis of long-term data on patients treated for the disease years ago with standard regimens of immunotherapy and a chemotherapy combination known as CHOP suggests that many of those patients can now be considered cured.
 
 AI cancer tools may be using visual shortcuts rather than true biology
 
AI cancer tools may be using visual shortcuts rather than true biologyNew research warns that popular deep learning systems trained for cancer pathology may be relying on hidden shortcuts rather than genuine biological signals.
 
 
 Combination therapy may help overcome barrier in early-stage prostate cancer treatment
 
Combination therapy may help overcome barrier in early-stage prostate cancer treatmentA multi-institutional study led by Mayo Clinic and published in Cell Reports Medicine reports that pairing a next-generation immunotherapy with standard hormone therapy before surgery may help overcome a long-standing barrier in early-stage prostate cancer treatment.
 
 
 Wisdom Bioscience establishes Scientific Advisory Board to advance oral cancer diagnostics and screening
 
Wisdom Bioscience establishes Scientific Advisory Board to advance oral cancer diagnostics and screeningWisdom Bioscience, Inc., a biotechnology company pioneering non-invasive oral cancer diagnostics, today announced the formation of its Scientific Advisory Board (SAB) following the close of an initial funding round.
 
 
 Phase 2 clinical trial tests LMP744 for the treatment of first-time recurrent glioblastoma
 
Phase 2 clinical trial tests LMP744 for the treatment of first-time recurrent glioblastomaGibson Oncology, a clinical-stage private pharmaceutical company headquartered in Miami, announced it has entered Phase 2 clinical trials with LMP744 for the treatment of first-time recurrent glioblastoma patients.
 
 
 Breakthrough gene therapy for sickle cell disease remains out of reach in Africa
 
As Uganda rolls out mandatory nationwide screening of newborns for sickle cell disease this month, a gene therapy celebrated in the United States and Europe remains financially out of reach for most patients in Africa.
 
 
 Neem compound gedunin shows promise against pancreatic cancer
 
Ramadevi Subramani Reddy, Ph.D., remembers the neem tree from her childhood in India - a plant her grandmother used to treat everything from fevers to infections.
 
 
 Common cardio drugs proven safe in myeloma patients
 
Commonly prescribed cardiovascular medications—such as statins, diuretics, and blood pressure drugs—appear to have little or no negative impact on survival among people living with multiple myeloma, according to new international research.
 
 
 A new standard for preventing post-surgery kidney cancer relapse
 
Patients with a common form of kidney cancer called clear cell renal cell carcinoma (ccRCC) who have a high risk of recurrence after surgery showed significantly improved disease-free survival when treated with an oral combination regimen that includes belzutifan, a HIF-2α inhibitor, given with standard immune therapy pembrolizumab.
 
 
 Extra copies of chromosome 1q may play key role in the earliest stages of pancreatic cancer
 
Researchers at the Johns Hopkins Kimmel Cancer Center and its Ludwig Center uncovered new evidence that extra copies of a specific chromosome segment - chromosome 1q - may play a key role in the earliest stages of pancreatic cancer development.
 
 
 Serial liquid biopsies reveal evolution in advanced prostate cancer
 
A new study using serial liquid biopsies to track how metastatic prostate cancer evolves under treatment pressure showed that androgen receptor (AR) alterations consistently emerged and were linked to poorer outcomes across therapies.
 
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