Poop pills could help cancer patients respond to immunotherapy while reducing toxic side effects

	Oncology
	The latest oncology news from News Medical

	Poop pills could help cancer patients respond to immunotherapy while reducing toxic side effects Fecal microbiota transplants (FMT), can dramatically improve cancer treatment, suggest two groundbreaking studies published in the prestigious Nature Medicine journal.

	Lifetime heavy drinking sharply raises colorectal cancer risk, major US study finds Lifetime alcohol intake, not just recent drinking, is associated with colorectal cancer risk in older adults followed in the PLCO Cancer Screening Trial. Heavy and consistent long-term drinking was linked to higher colorectal cancer risk, while alcohol cessation was associated with lower odds of early, nonadvanced adenomas.

	AI-supported mammography improves early detection of breast cancer Artificial intelligence (AI)-supported mammography identifies more cancers during screening and reduces the rate of breast cancer diagnosis by 12% in the years following, finds the first randomised controlled trial of its kind involving over 100,000 Swedish women published in The Lancet journal.

			Researchers develop blood test to find pancreatic ductal adenocarcinoma National Institutes of Health (NIH)-supported investigators have developed a blood test to find pancreatic ductal adenocarcinoma, one of the deadliest forms of cancer.

			Gut microbiome may be a central player in the body's response to cancer A new study reveals how bacteria in the gut can help determine whether the amino acid asparagine from the diet will feed tumor growth or activate immune cells against the cancer, according to researchers at Weill Cornell Medicine.

			Two-pronged therapeutic technology for cancer wins Pfizer Prize for Biomedical Research 2026 Whereas conventional treatments such as chemotherapy and radiotherapy show their limitations in battling certain advanced cancers, immunotherapy and therapeutic vaccines have opened up a new realm of hope for patients.

			New prevention strategy can reduce deadly ovarian cancer risk by nearly 80% A prevention strategy developed by Canadian researchers can reduce the risk of the most common and deadly form of ovarian cancer by nearly 80 per cent, according to a new study published today in JAMA Network Open by researchers at the University of British Columbia (UBC).

	Treating desmoplastic melanoma with immunotherapy before surgery can shrink or eliminate tumors New results from a clinical trial co-led by UCLA investigators demonstrate how treating desmoplastic melanoma, a rare and aggressive skin cancer, with immunotherapy before surgery can dramatically shrink or even eliminate tumors, sparing patients from more aggressive surgeries and preserving their quality of life.

	Genetic ancestry influences tumor biology and survival in head and neck cancers Genetic ancestry plays a key role in determining the behavior of head and neck tumors and may help explain why African-American patients survive for half as long as their counterparts of European ancestry, according to a new review study led by researchers from the University of Maryland School of Medicine's (UMSOM) Institute for Genome Sciences (IGS) and the University of Maryland Greenebaum Comprehensive Cancer Center (UMGCCC).

	Four-biomarker blood panel enhances the detection of pancreatic ductal adenocarcinoma A four-biomarker blood panel of aminopeptidase N (ANPEP), polymeric immunoglobulin receptor (PIGR), CA19-9, and thrombospondin-2 (THBS2) enhanced the detection of pancreatic ductal adenocarcinoma (PDAC) compared to measuring CA19-9 levels alone.

	Researchers identify key factor to help improve treatment for glioblastoma A groundbreaking study from Brown University Health researchers has identified a crucial factor that may help improve treatment for glioblastoma, one of the most aggressive and common forms of adult brain cancer.

	Novel laser focal therapy device shows promising results for prostate cancer treatment Because treatment of the whole prostate can lead to long-term side effects in patients with prostate cancer, interest in minimally invasive, focal treatment options has been growing for certain patients.

	ERC Proof of Concept grant supports promising CRISPR-based cancer treatment research Microbiologist John van der Oost of Wageningen University & Research (WUR) has received an ERC Proof of Concept grant to further develop a promising CRISPR-based approach to cancer treatment. With funding of €150,000, he and researcher Christian Südfeld will spend the next eighteen months working on a method to kill cancer cells from within, while sparing healthy cells as much as possible.

	Time of radiotherapy can influence the effectiveness of cancer treatment A team of researchers from the Andalusian Centre for Molecular Biology and Regenerative Medicine (CABIMER) and the University of Seville, in collaboration with the Virgen Macarena University Hospital, have identified a fundamental mechanism that links the 24-hour circadian cycle to the precise repair of DNA breaks.

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