Antibodies - Overcoming Cancer Drug Resistance: A Novel Gold Nanoparticle Therapy
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[Application Note] Discover How to Optimize ADC Internalization Assays for Enhanced ADC Development[Application Note] Discover How to Optimize ADC Internalization Assays for Enhanced ADC Development

Efficient internalization is critical to ADC efficacy. This application note reveals optimized assay conditions—such as pH-sensitive dye usage, antibody/reagent ratios, and time-course kinetics—for accurate measurement in HER2+ and CD20+ models. Gain actionable guidance for improving antibody screening and internalization profiling.

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   Overcoming Cancer Drug Resistance: A Novel Gold Nanoparticle TherapyOvercoming Cancer Drug Resistance: A Novel Gold Nanoparticle Therapy
 
Gold nanoparticles conjugated with trastuzumab enhance ovarian cancer cell death, particularly in drug-resistant cases, offering a potential precision therapy.
 
   Engineered CD40 antibody shrinks tumors and induces remissionEngineered CD40 antibody shrinks tumors and induces remission
 
Over the past 20 years, a class of cancer drugs called CD40 agonist antibodies have shown great promise-and induced great disappointment.
 
 New llama antibody-based treatment improves brain function in schizophrenia models
 
New llama antibody-based treatment improves brain function in schizophrenia modelsWhile current treatments for schizophrenia - a mental illness affecting 1% of the world's population - can reduce certain symptoms, they have little effect on the cognitive deficits affecting the daily life of patients.
 
 
 New antibody delivery system boosts Alzheimer's treatment in mice
 
New antibody delivery system boosts Alzheimer's treatment in miceA newly engineered antibody transport vehicle targeting the transferrin receptor enables enhanced delivery of anti-amyloid antibodies to the brains of mouse models of Alzheimer's disease, researchers report.
 
 
 Different anti-PD-L1 antibodies show varied results in tumor growth inhibition
 
Different anti-PD-L1 antibodies show varied results in tumor growth inhibitionImmune checkpoint inhibitors (ICIs), a powerful form of immunotherapy, have revolutionized cancer treatment by unleashing the body's own immune system to fight tumors.
 
 
 Antibodies.com expands UK headquarters with new 5x larger facilities in Cambridge to accommodate rapid growth
 
Antibodies.com expands UK headquarters with new 5x larger facilities in Cambridge to accommodate rapid growthAntibodies.com, a trusted provider of high-quality biological reagents for life science researchers, today announced the expansion of its UK headquarters with a move to Cambridge Technopark to accommodate the Company's rapid growth.
 
 
 Immunoglobulin replacement therapy not associated with reduced risk of serious infections in patients with CLL
 
Immunoglobulin replacement therapy not associated with reduced risk of serious infections in patients with CLLIn patients with chronic lymphocytic leukemia (CLL), regular treatment with immunoglobulin replacement therapy was not associated with a reduced risk of serious infections requiring hospitalization, according to a study published in Blood Advances.
 
 
 New imaging technique reveals how antibodies reshape cancer cell receptors
 
New imaging technique reveals how antibodies reshape cancer cell receptorsA new study shows how the single-molecule organization of receptors in a cellular context determines the function of antibodies, opening up new pathways for the development of cancer immunotherapies.
 
 
 Dengue antibody may block the spread of Zika virus in vulnerable areas of the body
 
Dengue antibody may block the spread of Zika virus in vulnerable areas of the bodyA new study from the University of Alabama at Birmingham reveals that an antibody originally designed to fight dengue virus may also block the spread of Zika virus in vulnerable areas of the body - including the reproductive organs.
 
 
 CD276 Antibody Strategy Offers Hope For Immune-Resistant Lung Tumors
 
CD276 Antibody Strategy Offers Hope For Immune-Resistant Lung TumorsThe study highlights 8H8_SDIE's role in activating NK cells against NSCLC, offering a new strategy for patients resistant to conventional immunotherapies.
 
 

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