| Flow Cytometry: Combinatorial Approaches to Cell Counting |
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May 21, 2019 |
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The latest flow cytometry news from News Medical |
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 | | |  Overcoming Challenges when Designing a Multicolor Flow Cytometry Panel
Flow cytometry is a platform with the power to carry out the identification and characterization of multiple antigens at one time. At the same time, it must be noted that when more antigens and fluorochromes are employed, the experimental design becomes much more complex. To deal with this task, it is useful to consider the following five steps.
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| | |  Aneuploidy is defined as a chromosomal aberration involving either an addition or deletion of chromosomes compared to the ‘normal' number of 46 chromosomes. Flow cytometry is a useful tool for detecting anueploidy. | | | | |  Professor Douglas Kell has developed technology using flow cytometry which detects and counts individual bacteria in a urine sample, and can determine which antibiotic is the most efficient at killing those particular bacteria. | | | | |  Using flow cytometry, researchers have discovered that mucosal-associated invariant T (MAIT) cells, which are usually abundant in the liver, are deficient in patients with chronic hepatitis D. | | | | |  High sensitivity flow cytometry has revealed that 0.01% cells in the lymph nodes express Aire, a gene that regulates expression of tissue-restricted antigens in medullary thymic epithelial cells and has been associated with autoimmune diseases. | | | | |  Thirteen-color flow cytometry will now be a routine part of clinical testing, as the Athena flow cytometer by Cytek Biosciences is approved for clinical diagnostic use in hospitals, laboratories and clinics across China. | |
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