Flow Cytometry - Powerful imaging mass cytometry could revolutionize the diagnosis of lupus nephritis
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Application Note: Innovation in the Cell Therapy Workflow for Anti-BCMA CAR-T DevelopmentApplication Note: Innovation in the Cell Therapy Workflow for Anti-BCMA CAR-T Development

Cell and gene therapy manufacturing methods are at the technological edge of immunology and virology research and development. This application note demonstrates how the WOLF G2® Cell Sorter enables analyses and sorting of effective cell therapy agents at multiple steps of the cell therapy production workflow.

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   Powerful imaging mass cytometry could revolutionize the diagnosis of lupus nephritisPowerful imaging mass cytometry could revolutionize the diagnosis of lupus nephritis
 
Chandra Mohan, Hugh Roy and Lillie Cranz Cullen Endowed Professor of biomedical engineering, is reporting the first use of the powerful imaging mass cytometry (IMC) to examine the kidneys of patients with lupus (systemic lupus erythematosus), an autoimmune disease that can affect multiple organs and become fatal, and to diagnose lupus nephritis (LN) in those patients.
 
   The critical role of flow cytometry in CAR+ T-Cell trialsThe critical role of flow cytometry in CAR+ T-Cell trials
 
In this interview, Ryan Muise talks to AZoNetwork about the added value of using flow cytometry in CAR T-Cell clinical trials.
 
   Discovering Novel Antimicrobials with Flow CytometryDiscovering Novel Antimicrobials with Flow Cytometry
 
An important and effective method of discovering novel antimicrobials is utilizing flow cytometry, which will be the focus of this article.
 
   Study reveals CMPK-2 protein-coding gene as a potent inhibitor of flavivirusesStudy reveals CMPK-2 protein-coding gene as a potent inhibitor of flaviviruses
 
CMPK2 identified as a potential pan-flavivirus inhibitor, restricting virus replication and providing a basis for developing new antiviral treatments.
 
   High-Throughput Assay to Analyze the Effects of CAR-T Cells Using Image CytometryHigh-Throughput Assay to Analyze the Effects of CAR-T Cells Using Image Cytometry
 
The April 2023 issue of SLAS Discovery contains six full-length articles and one mini-review covering high-throughput screening (HTS) for protease-inhibiting drugs, high-content phenotypic screening and other life sciences research.
 
 

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