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The latest drug discovery news from News Medical |
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 A Practical Guide to Molecular Interaction Analysis
Unlock deeper insight into molecular binding with this practical guide to Isothermal Titration Calorimetry. Learn how to quantify interactions, interpret thermodynamics, validate high throughput assays, and measure enzyme kinetics with confidence. Essential reading for researchers and drug developers advancing molecular level understanding.
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 Rethinking Sustainable Consumables for Drug Discovery Workflows
Automation, sample storage, and reproducibility are essential in drug discovery, but sustainability is becoming equally important. This interview explores how paper-based labware is being engineered for automated liquid handling, cryogenic storage, and high-throughput environments. Learn how sustainable materials are evolving to support modern drug discovery workflows without sacrificing compatibility, durability, or laboratory performance.
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| |  | | | | |  How AI and QSAR Modeling Accelerate Ligand-Based Drug Design Ligand-based drug design combines AI and QSAR modeling to prioritize drug candidates, minimizing preclinical failures and accelerating therapeutic development. | | | | | | |  How Photopharmacology Uses Light-Controlled Drug Activation Photopharmacology combines light and drug action, offering reversible control over biological pathways, transforming precision medicine and drug discovery. | |
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|  | | |  Antibody-drug conjugates are rapidly expanding cancer therapies, with 19 approved globally and many more in development, but their success depends on better targets, payloads, linkers, dosing, and patient selection. The Cell review shows that next-generation ADCs could widen treatment options, but safety, resistance, tumor heterogeneity, and clinical translation remain major barriers. | | | | |  Organoids are miniature tissue or organ models formed by stem cells (including pluripotent stem cells, tissue-specific adult stem cells, etc.) or progenitor cells in an in vitro three-dimensional culture system, which possess structural features and partial functions analogous to their corresponding in vivo organs. | | | | |  Increasing bone density in patients with a rare genetic condition that causes bones to break easily does not prevent fractures, a large clinical trial has found. | | | | |  Researchers at The University of Texas Medical Branch (UTMB) have identified how a key enzyme called ATR protects DNA from breaking when cells copy damaged genetic material, a discovery that could affect how certain cancer drugs are developed. | | | | |  UCLA Health researchers have identified a potential drug target for treating Fragile X syndrome, the most common genetic cause of intellectual disability and autism that affects roughly 1 in 2,000 boys. | | | | |  Guidance on compressed gas risk assessment within GMP utilities, addressing classification, system criticality, and strategies. | |
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