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The latest drug discovery news from News Medical |
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 Giving Biologists Their Time Back with Automated Cell Culture
Drug discovery teams are under constant pressure to move faster, yet routine cell culture remains one of the most time consuming and labour intensive parts of biological research. This eBook explores how automating cell culture workflows, including 2D cell lines and advanced 3D models such as organoids, spheroids and iPSCs, can significantly reduce hands on time while improving consistency and scalability.
Learn how automated feeding, passaging and monitoring workflows have enabled reductions of more than 90% in manual culture time for some applications, allowing scientists to spend less time on routine tasks and more time on the science that drives discovery, from early screening through validation.
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 PROTAC Breakthrough Reshapes Targeted Drug Discovery
The FDA approval of vepdegestrant marks a major milestone for targeted protein degradation research. Unlike traditional inhibitors, PROTACs remove disease-driving proteins entirely, opening new therapeutic possibilities for previously difficult targets. Advances in live-cell degradation analysis, endogenous protein monitoring, and mechanistic screening are now accelerating next-generation degrader development across drug discovery.
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| |  | | | | |  New TriPcide Antibiotics Kill Dormant MRSA Without Resistance The study on TriPcides reveals their ability to combat MRSA and dormant bacteria, offering a new strategy to address antimicrobial resistance in public health. | | | | | | |  Phase two clinical trial demonstrates dramatic mobility gains in children with severe fibrous dysplasia Fibrous dysplasia is a rare skeletal disorder in which normal bone is gradually replaced by weak fibro-osseous tissue, leading to fractures, pain, deformities, and severe mobility impairment. In many patients, diseased bone tissue produces excessive amounts of fibroblast growth factor-23 (FGF23), a hormone that causes phosphate loss through the kidneys. | | | | | | |  Graph neural networks accelerate drug discovery for complex bone diseases Announcing a new publication for Acta Materia Medica journal. Traditional Chinese medicine has shown therapeutic potential in treating osteoarthritis (OA) by regulating inflammation and maintaining cartilage homeostasis. | | | | | | | __639155575552398044_multisizecolor_195_custom.jpg) Study explores alternatives to clinical trials in rural healthcare research Randomized controlled trials (RCTs) are challenging to conduct in rural areas, however, a new Griffith University study examined how high-quality research could be conducted when RCTs were not possible. | |
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