| |  Microfluidics is an upcoming technology that has been used in many areas of chemical and biological research. One valuable application of this technique is in studying protein-protein interactions in cell biology. This is essential in allowing insights into cell signaling and gene regulatory pathways for further understanding of biological processes. | |
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| |  In most clinical applications, the monoclonal antibodies (mAbs) used are of murine origin; however, the small spleen of the mouse is limited in its ability to generate antibodies. Also, the mice used for laboratory experiments are usually inbred in a controlled environment, further restricting their ability to demonstrate diverse immune responses. | |
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| |  Researchers at the University of Queensland have found that a topical formulation containing cannabidiol (CBD) is effective at killing bacterial skin infections and could form the basis of a new drug. | |
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| |  Researchers have created fruit fly “avatars” that have helped to guide treatment for a man who had terminal colon cancer. The team genetically engineered flies that had the same mutations as the man’s tumor and then tested different drug combinations to see which ones kept the flies alive. Doctors eventually settled on a drug combination that was the most effective and administered it to the man. | |
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| |  RNA interference is a biological process that has evolved with the evolution of mammals and plays an important role in transient and long-term blocking of protein expression. Short Hairpin RNA (shRNA) interference has many therapeutic applications, and research is still ongoing into new areas of focus. | |
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| |  A new discovery by researchers at Columbia University Vagelos College of Physicians and Surgeons could fix one of the major shortcomings of current gene-editing tools, including CRISPR, and offer a powerful new approach for genetic engineering and gene therapy. | |
