SARS-CoV-2 Omicron XBB.1.5, CA.3.1, and CH.1.1 exhibit remarkable antibody resistance
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 The "Great Escape" by SARS-CoV-2 XBB.1The "Great Escape" by SARS-CoV-2 XBB.1
 
In a recent article published in the Lancet Microbe, researchers in the Netherlands and the United Kingdom quantified the antigenic diversity of new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) subvariants, BQ.1.1, BM.1.1.1, and XBB.1, all derivatives of the variant of concern (VOC) Omicron, which emerged in late 2022.
 
 
 SARS-CoV-2 Omicron XBB.1.5, CA.3.1, and CH.1.1 exhibit remarkable antibody resistanceSARS-CoV-2 Omicron XBB.1.5, CA.3.1, and CH.1.1 exhibit remarkable antibody resistance
 
In a recent study posted to bioRxiv* preprint server, researchers at Ohio State University examined the degree of neutralizing antibody (nAb) evasion by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron XBB.1.5, CA.3.1, and CH.1.1 subvariants.
 
   Study shows increase in medical encounters six months post-SARS-CoV-2 infection, with vaccination lowering persistent symptoms riskStudy shows increase in medical encounters six months post-SARS-CoV-2 infection, with vaccination lowering persistent symptoms risk
 
Researchers identified factors related to PCC [post-COVID-19 (coronavirus disease 2019] symptoms and assessed changes in PCC medical visits.
 
   Analysis of seemingly recovered COVID-19 patients indicates that SARS-CoV-2 infection can persist significantly longer than suggested by PCR-negative testsAnalysis of seemingly recovered COVID-19 patients indicates that SARS-CoV-2 infection can persist significantly longer than suggested by PCR-negative tests
 
Scientists have described the infection dynamics and clinical features of PCR-negative patients who eventually died due to the worsening of COVID-19.
 
   Researchers find that study results converge on a consistent relationship between antibody levels and protection from COVID-19Researchers find that study results converge on a consistent relationship between antibody levels and protection from COVID-19
 
Researchers described the factors associated with protection, protection thresholds, and immunobridging in COVID-19 patients.
 
 Bivalent BA.4-5 or BA.1 mRNA-booster given as a fourth dose associated with increased protection against COVID-19 hospitalization and death
 
Bivalent BA.4-5 or BA.1 mRNA-booster given as a fourth dose associated with increased protection against COVID-19 hospitalization and deathResearchers compared the efficiency of the SARS-CoV-2 Omicron BA.4-5 and BA.1 bivalent mRNA-booster vaccines.
 
 
 How is long COVID diagnosed in adults?
 
How is long COVID diagnosed in adults?In a recent study, researchers enlisted important points concerning post-coronavirus disease 2019 (COVID-19) or long COVID diagnosis among adults.
 
 
 Study suggests Alzheimer’s disease diagnosis is associated with higher levels of soluble ACE2 in the human brain
 
Study suggests Alzheimer’s disease diagnosis is associated with higher levels of soluble ACE2 in the human brainResearchers investigated ACE2 (angiotensin-converting enzyme 2) levels among individuals with AD (Alzheimer’s disease).
 
 
 The efficacy of low-dose fluvoxamine compared with placebo for treating mild to moderate COVID-19 in the US
 
The efficacy of low-dose fluvoxamine compared with placebo for treating mild to moderate COVID-19 in the USResearchers evaluated the efficacy of low-dosage fluvoxamine (50 mg two times a day) over 10 days in the management of mild and moderate-SARS-CoV-2 infections in the US.
 
 
 People with hybrid immunity are the most protected against severe COVID-19 and reinfection
 
People with hybrid immunity are the most protected against severe COVID-19 and reinfectionA University of Calgary research group - which includes several Bachelor of Health Sciences alumni joined forces with members of the World Health Organization to tackle a global health question.
 
 
 Researchers estimate COVID-19 Omicron variant mortality in Denmark
 
Researchers estimate COVID-19 Omicron variant mortality in DenmarkA recent Eurosurveillance study investigated how coincidental infections influenced COVID-19 mortality estimates after the emergence of the Omicron variant.
 
 
 How effective are prior SARS-CoV-2 infections and hybrid immunity against Omicron breakthrough infections?
 
How effective are prior SARS-CoV-2 infections and hybrid immunity against Omicron breakthrough infections?Researchers performed a systematic review and meta-regression study to determine the breadth and duration of the protective immunity conferred by previous severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and hybrid immunity.
 
 
 What was the prevalence of adverse events following first and second dose COVID-19 vaccinations in England?
 
What was the prevalence of adverse events following first and second dose COVID-19 vaccinations in England?A recent Eurosurveillance study focused on estimating the incidence of a prespecified list of adverse events following the first and second doses of the COVID-19 vaccination.
 
 
 What is the association between COVID-19, cardiovascular disease, and mortality?
 
What is the association between COVID-19, cardiovascular disease, and mortality?In a new study, researchers evaluated the association between COVID-19 (coronavirus disease 2019) and CVD (cardiovascular disease) and/or death.
 
 
 New trial evaluates Omicron BA.1–adapted BNT162b2 vaccine in older adults
 
New trial evaluates Omicron BA.1–adapted BNT162b2 vaccine in older adultsResearchers reported the findings of the phase III trial evaluating the Omicron BA.1–adapted mono and bivalent BNT162b2 coronavirus disease 2019 (COVID-19) vaccine in 55-year-old adults. These individuals had already received three 30μg doses of the BNT162b2 vaccine.
 
 
 Exploring the infectivity, transmissibility, and immunological resistance characteristics of SARS-CoV-2 Omicron XBB.1.5 strain
 
Exploring the infectivity, transmissibility, and immunological resistance characteristics of SARS-CoV-2 Omicron XBB.1.5 strainResearchers performed an epidemic dynamic analysis to assess the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern (VOC)’s sub-VOC XBB.1.5 characteristics.
 
 
 Heart symptoms persist in 10% of patients with long-COVID
 
Heart symptoms persist in 10% of patients with long-COVIDIn a recent study posted to the medRxiv* preprint server, researchers described the long-term cardiac symptoms associated with coronavirus disease 2019 (COVID-19).
 
 
 Tight transmission bottlenecks may limit the evolution of SARS-CoV-2 variants
 
Tight transmission bottlenecks may limit the evolution of SARS-CoV-2 variantsA new study describes that tight transmission bottlenecks restrict the evolution of SARS-CoV-2 in the transmission chain. SARS-CoV-2 is the causative pathogen of the COVID-19 pandemic.
 
 
 What are the major findings of long COVID research?
 
What are the major findings of long COVID research?Researchers explored existing literature on long coronavirus disease (COVID). They highlighted key immunological findings, similarities with other diseases, symptoms, and associated pathophysiological mechanisms, and diagnostic and therapeutic options, including COVID-19 vaccinations.
 
 
 In silico study suggests SARS-CoV-2 Omicron XBB.1.5 strain to be more infective than previous strains
 
In silico study suggests SARS-CoV-2 Omicron XBB.1.5 strain to be more infective than previous strainsResearchers performed an in silico analysis to estimate the relative risks of recently emerged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants.